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One or more keywords matched the following items that are connected to Perrimon, Norbert
Item TypeName
Academic Article Cellular functions of proteoglycans--an overview.
Academic Article Specificity of receptor tyrosine kinase signaling pathways: lessons from Drosophila.
Academic Article Polarity determination in the Drosophila eye: a novel role for unpaired and JAK/STAT signaling.
Academic Article The roles of JAK/STAT signaling in Drosophila immune responses.
Academic Article The Jak/STAT pathway in model organisms: emerging roles in cell movement.
Academic Article BMP signaling is required for controlling somatic stem cell self-renewal in the Drosophila ovary.
Academic Article The retinoic-like juvenile hormone controls the looping of left-right asymmetric organs in Drosophila.
Academic Article The neurogenic genes egghead and brainiac define a novel signaling pathway essential for epithelial morphogenesis during Drosophila oogenesis.
Academic Article FOXO/4E-BP signaling in Drosophila muscles regulates organism-wide proteostasis during aging.
Academic Article The PDGF/VEGF receptor controls blood cell survival in Drosophila.
Academic Article Weckle is a zinc finger adaptor of the toll pathway in dorsoventral patterning of the Drosophila embryo.
Academic Article corkscrew encodes a putative protein tyrosine phosphatase that functions to transduce the terminal signal from the receptor tyrosine kinase torso.
Academic Article I-SceI endonuclease, a new tool for studying DNA double-strand break repair mechanisms in Drosophila.
Academic Article Entry is a rate-limiting step for viral infection in a Drosophila melanogaster model of pathogenesis.
Academic Article Dual function of Ras in Raf activation.
Academic Article An image score inference system for RNAi genome-wide screening based on fuzzy mixture regression modeling.
Academic Article Drosophila as a model for interorgan communication: lessons from studies on energy homeostasis.
Academic Article Signalling pathways initiated by receptor protein tyrosine kinases in Drosophila.
Academic Article An integrative approach to ortholog prediction for disease-focused and other functional studies.
Academic Article Control of proinflammatory gene programs by regulated trimethylation and demethylation of histone H4K20.
Academic Article Sarcomere formation occurs by the assembly of multiple latent protein complexes.
Academic Article A genome-wide transgenic resource for conditional expression of Drosophila microRNAs.
Academic Article Doublesex surprises.
Academic Article Use of a label-free quantitative platform based on MS/MS average TIC to calculate dynamics of protein complexes in insulin signaling.
Academic Article The era of systems developmental biology.
Academic Article Apicobasal polarization: epithelial form and function.
Academic Article Comparative analysis of argonaute-dependent small RNA pathways in Drosophila.
Academic Article Hierarchical rules for Argonaute loading in Drosophila.
Academic Article Spatial control of the actin cytoskeleton in Drosophila epithelial cells.
Academic Article The promise and perils of Wnt signaling through beta-catenin.
Academic Article Role of heparan sulfate proteoglycans in cell signaling and cancer.
Academic Article The Wingless morphogen gradient is established by the cooperative action of Frizzled and Heparan Sulfate Proteoglycan receptors.
Academic Article High-throughput RNAi screening in cultured cells: a user's guide.
Academic Article Tailoring the genome: the power of genetic approaches.
Academic Article In vivo RNAi: today and tomorrow.
Academic Article The torso receptor tyrosine kinase can activate Raf in a Ras-independent pathway.
Academic Article A case study of the reproducibility of transcriptional reporter cell-based RNAi screens in Drosophila.
Academic Article Signaling mechanisms controlling cell fate and embryonic patterning.
Academic Article Do-it-yourself RNAi made easy?
Academic Article Marelle acts downstream of the Drosophila HOP/JAK kinase and encodes a protein similar to the mammalian STATs.
Academic Article Drosophila as a model system to study autophagy.
Academic Article Dual functions of wingless in the Drosophila leg imaginal disc.
Academic Article Evidence for engrailed-independent wingless autoregulation in Drosophila.
Academic Article Inactivation of Drosophila Huntingtin affects long-term adult functioning and the pathogenesis of a Huntington's disease model.
Academic Article Embryonic multipotent progenitors remodel the Drosophila airways during metamorphosis.
Academic Article The torso pathway in Drosophila: a model system to study receptor tyrosine kinase signal transduction.
Academic Article Expanded polyglutamine domain possesses nuclear export activity which modulates subcellular localization and toxicity of polyQ disease protein via exportin-1.
Academic Article Presenilin affects arm/beta-catenin localization and function in Drosophila.
Academic Article Developmental roles of heparan sulfate proteoglycans in Drosophila.
Academic Article Drosophila Wnt/Fz pathways.
Academic Article Proteomic and functional genomic landscape of receptor tyrosine kinase and ras to extracellular signal-regulated kinase signaling.
Concept Models, Molecular
Concept Models, Structural
Concept Models, Animal
Concept Models, Genetic
Concept Models, Immunological
Concept Disease Models, Animal
Concept Models, Biological
Concept Xenograft Model Antitumor Assays
Academic Article Receptor tyrosine kinases in Drosophila development.
Academic Article Of flies and men: insights on organismal metabolism from fruit flies.
Academic Article Drosophila as a model for context-dependent tumorigenesis.
Academic Article Mechanisms of skeletal muscle aging: insights from Drosophila and mammalian models.
Academic Article Mechanisms of muscle growth and atrophy in mammals and Drosophila.
Academic Article Functional screening in Drosophila identifies Alzheimer's disease susceptibility genes and implicates Tau-mediated mechanisms.
Academic Article Systematic screen of chemotherapeutics in Drosophila stem cell tumors.
Academic Article Modeling metabolic homeostasis and nutrient sensing in Drosophila: implications for aging and metabolic diseases.
Academic Article Comparative analysis of the transcriptome across distant species.
Academic Article Mechanical Allostery: Evidence for a Force Requirement in the Proteolytic Activation of Notch.
Academic Article Fruit flies on the front line: the translational impact of Drosophila.
Academic Article The torso pathway in Drosophila: a model system to study receptor tyrosine kinase signal transduction.
Grant Drosophila resources for modeling human diseases
Grant The Flybase Diversity Action Plan
Grant Characterization of the Insulin to Autophagy Pathway in Muscles
Grant Viral Immunity in Drosophila
Grant Using Drosophila for in vivo drug screens to selectively target cancer stem cells
Grant Large-Scale High-Confidence Binary Protein Interaction Network for Drosophila
Grant Network Topology in Cell Signaling
Grant Development of Validated Drosophila in vivo RNAi Models of Human Diseases
Grant Proliferative control of normal &oncogenically transformed stem cells in vivo
Grant Development of Validated Drosophila in vivo RNAi Models of Human Diseases
Academic Article Loss-of-function genetic tools for animal models: cross-species and cross-platform differences.
Academic Article miR-263a Regulates ENaC to Maintain Osmotic and Intestinal Stem Cell Homeostasis in Drosophila.
Academic Article Midgut-Derived Activin Regulates Glucagon-like Action in the Fat Body and Glycemic Control.
Academic Article eUnaG: a new ligand-inducible fluorescent reporter to detect drug transporter activity in live cells.
Academic Article MARRVEL: Integration of Human and Model Organism Genetic Resources to Facilitate Functional Annotation of the Human Genome.
Academic Article Activin signaling mediates muscle-to-adipose communication in a mitochondria dysfunction-associated obesity model.
Grant Identification of Presinilin downstream targets in neuronal survival
Academic Article Blocking p62-dependent SMN degradation ameliorates spinal muscular atrophy disease phenotypes.
Grant Mapping protein communication between organs in homeostasis and disease
Grant Functional genomics resources for the Drosophila and broader research communities
Academic Article Drosophila as a Model for Tumor-Induced Organ Wasting.
Academic Article Drosophila melanogaster: a simple system for understanding complexity.
Academic Article HIF-independent synthetic lethality between CDK4/6 inhibition and VHL loss across species.
Academic Article Drosophila as a model for studying cystic fibrosis pathophysiology of the gastrointestinal system.
Academic Article A Drosophila model of oral peptide therapeutics for adult intestinal stem cell tumors.
Grant TRiP resources for modeling human disease
Academic Article Targeting metabolic pathways for extension of lifespan and healthspan across multiple species.
Academic Article BioLitMine: Advanced Mining of Biomedical and Biological Literature About Human Genes and Genes from Major Model Organisms.
Academic Article mTORC1 promotes cell growth via m6A-dependent mRNA degradation.
Academic Article Proteomics of protein trafficking by in vivo tissue-specific labeling.
Academic Article A Drosophila model of oral peptide therapeutics for adult Intestinal Stem Cell tumors.
Academic Article A genetic model of methionine restriction extends Drosophila health- and lifespan.
Search Criteria
  • Modelling
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.