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Nelfinavir, A lead HIV protease inhibitor, is a broad-spectrum, anticancer agent that induces endoplasmic reticulum stress, autophagy, and apoptosis in vitro and in vivo.
A phase I trial of the HIV protease inhibitor nelfinavir in adults with solid tumors.
Nelfinavir, a new anti-cancer drug with pleiotropic effects and many paths to autophagy.
Combining Nelfinavir With Chloroquine Inhibits In Vivo Growth of Human Lung Cancer Xenograft Tumors.