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One or more keywords matched the following items that are connected to Blacklow, Stephen
Item TypeName
Academic Article Protein folding and calcium binding defects arising from familial hypercholesterolemia mutations of the LDL receptor.
Academic Article Cysteine-rich module structure reveals a fulcrum for integrin rearrangement upon activation.
Academic Article Structural independence of ligand-binding modules five and six of the LDL receptor.
Academic Article The zinc finger-associated SCAN box is a conserved oligomerization domain.
Academic Article Folding determinants of LDL receptor type A modules.
Academic Article Notch subunit heterodimerization and prevention of ligand-independent proteolytic activation depend, respectively, on a novel domain and the LNR repeats.
Academic Article Solution structure of the sixth LDL-A module of the LDL receptor.
Academic Article Backbone dynamics of a module pair from the ligand-binding domain of the LDL receptor.
Academic Article Definition of EGF-like, closely interacting modules that bear activation epitopes in integrin beta subunits.
Academic Article Folding and binding integrity of variants of a prototype ligand-binding module from the LDL receptor possessing multiple alanine substitutions.
Academic Article Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexes.
Academic Article The SCAN domain of ZNF174 is a dimer.
Academic Article The folding and structural integrity of the first LIN-12 module of human Notch1 are calcium-dependent.
Academic Article A two-module region of the low-density lipoprotein receptor sufficient for formation of complexes with apolipoprotein E ligands.
Academic Article Evidence for increased exposure of the Notch1 metalloprotease cleavage site upon conversion to an activated conformation.
Academic Article Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia.
Academic Article Nuclear magnetic resonance structure of a prototype Lin12-Notch repeat module from human Notch1.
Academic Article Structure of an LDLR-RAP complex reveals a general mode for ligand recognition by lipoprotein receptors.
Academic Article Effects of S1 cleavage on the structure, surface export, and signaling activity of human Notch1 and Notch2.
Academic Article Implications for familial hypercholesterolemia from the structure of the LDL receptor YWTD-EGF domain pair.
Academic Article Identification of a conserved negative regulatory sequence that influences the leukemogenic activity of NOTCH1.
Academic Article Structure and physiologic function of the low-density lipoprotein receptor.
Academic Article Leukemia-associated mutations within the NOTCH1 heterodimerization domain fall into at least two distinct mechanistic classes.
Academic Article A trimeric structural domain of the HIV-1 transmembrane glycoprotein.
Academic Article Origins of peptide selectivity and phosphoinositide binding revealed by structures of disabled-1 PTB domain complexes.
Academic Article Phosphoinositide binding by the disabled-1 PTB domain is necessary for membrane localization and Reelin signal transduction.
Academic Article Molecular basis of familial hypercholesterolaemia from structure of LDL receptor module.
Academic Article Two functionally distinct forms of a retroviral receptor explain the nonreciprocal receptor interference among subgroups B, D, and E avian leukosis viruses.
Academic Article Deletion-based mechanisms of Notch1 activation in T-ALL: key roles for RAG recombinase and a conserved internal translational start site in Notch1.
Academic Article A zinc clasp structure tethers Lck to T cell coreceptors CD4 and CD8.
Academic Article Evidence that familial hypercholesterolemia mutations of the LDL receptor cause limited local misfolding in an LDL-A module pair.
Academic Article Conformational locking upon cooperative assembly of notch transcription complexes.
Academic Article Structure of the Notch1-negative regulatory region: implications for normal activation and pathogenic signaling in T-ALL.
Academic Article Pure translation display.
Academic Article A trimeric subdomain of the simian immunodeficiency virus envelope glycoprotein.
Concept Amino Acid Sequence
Concept Repetitive Sequences, Amino Acid
Academic Article Intrinsic selectivity of Notch 1 for Delta-like 4 over Delta-like 1.
Academic Article A tail of two sites: a bipartite mechanism for recognition of notch ligands by mind bomb E3 ligases.
Academic Article Human NOTCH2 Is Resistant to Ligand-independent Activation by Metalloprotease Adam17.
Academic Article Electrostatic Interactions between Elongated Monomers Drive Filamentation of Drosophila Shrub, a Metazoan ESCRT-III Protein.
Academic Article STK40 Is a Pseudokinase that Binds the E3 Ubiquitin Ligase COP1.
Academic Article Bispecific Forkhead Transcription Factor FoxN3 Recognizes Two Distinct Motifs with Different DNA Shapes.
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  • Amino Acid Sequence
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.