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One or more keywords matched the following items that are connected to Rubin, Eric
Item TypeName
Academic Article A new site-specific integration system for mycobacteria.
Academic Article In vivo transposition of mariner-based elements in enteric bacteria and mycobacteria.
Academic Article The folate pathway is a target for resistance to the drug para-aminosalicylic acid (PAS) in mycobacteria.
Academic Article HIV-1 replication is differentially regulated by distinct clinical strains of Mycobacterium tuberculosis.
Academic Article Relics of selection in the mycobacterial genome.
Academic Article Host transcription in active and latent tuberculosis.
Academic Article Differential antibiotic susceptibilities of starved Mycobacterium tuberculosis isolates.
Academic Article A partner for the resuscitation-promoting factors of Mycobacterium tuberculosis.
Academic Article The complex relationship between mycobacteria and macrophages: it's not all bliss.
Academic Article The many roads to essential genes.
Academic Article Phthiocerol dimycocerosate transport is required for resisting interferon-gamma-independent immunity.
Academic Article Protein inactivation in mycobacteria by controlled proteolysis and its application to deplete the beta subunit of RNA polymerase.
Academic Article Genetic requirements for mycobacterial survival during infection.
Academic Article Mycobacterium tuberculosis inhibits macrophage responses to IFN-gamma through myeloid differentiation factor 88-dependent and -independent mechanisms.
Academic Article Mutually dependent secretion of proteins required for mycobacterial virulence.
Academic Article Function of a mycobacterial major facilitator superfamily pump requires a membrane-associated lipoprotein.
Academic Article Mycobacterium tuberculosis ESAT-6 exhibits a unique membrane-interacting activity that is not found in its ortholog from non-pathogenic Mycobacterium smegmatis.
Academic Article Characterization and transcriptome analysis of Mycobacterium tuberculosis persisters.
Academic Article Mycobacterial Esx-3 is required for mycobactin-mediated iron acquisition.
Academic Article MmpL3 is the cellular target of the antitubercular pyrrole derivative BM212.
Academic Article Genome-wide RNAi screen for host factors required for intracellular bacterial infection.
Academic Article Drosophila RNAi screen reveals CD36 family member required for mycobacterial infection.
Academic Article Scaling down: a PCR-based method to efficiently screen for desired knockouts in a high density Mycobacterium tuberculosis picked mutant library.
Academic Article A mycobacterial enzyme essential for cell division synergizes with resuscitation-promoting factor.
Academic Article Tuberculosis. Advances in laboratory diagnosis and drug susceptibility testing.
Academic Article Mycobacterium tuberculosis and the host response.
Academic Article Transposon site hybridization in Mycobacterium tuberculosis.
Academic Article Genes required for mycobacterial growth defined by high density mutagenesis.
Academic Article Increased sulfate uptake by E. coli overexpressing the SLC26-related SulP protein Rv1739c from Mycobacterium tuberculosis.
Academic Article Mycobacterium tuberculosis ClpP1 and ClpP2 function together in protein degradation and are required for viability in vitro and during infection.
Academic Article ESCRT factors restrict mycobacterial growth.
Academic Article Phage transposon mutagenesis.
Academic Article Variation among genome sequences of H37Rv strains of Mycobacterium tuberculosis from multiple laboratories.
Academic Article Systematic genetic nomenclature for type VII secretion systems.
Academic Article Global assessment of genomic regions required for growth in Mycobacterium tuberculosis.
Academic Article The active ClpP protease from M. tuberculosis is a complex composed of a heptameric ClpP1 and a ClpP2 ring.
Academic Article Protein complexes and proteolytic activation of the cell wall hydrolase RipA regulate septal resolution in mycobacteria.
Academic Article Comprehensive identification of conditionally essential genes in mycobacteria.
Academic Article Detecting genetic variability among different Mycobacterium tuberculosis strains using DNA microarrays technology.
Academic Article Toward a new therapy for tuberculosis.
Academic Article The granuloma in tuberculosis--friend or foe?
Academic Article Interaction and modulation of two antagonistic cell wall enzymes of mycobacteria.
Academic Article Lipidomic discovery of deoxysiderophores reveals a revised mycobactin biosynthesis pathway in Mycobacterium tuberculosis.
Academic Article Mycobacterium tuberculosis Rv2224c modulates innate immune responses.
Academic Article Genome-wide requirements for Mycobacterium tuberculosis adaptation and survival in macrophages.
Academic Article Drugs versus bugs: in pursuit of the persistent predator Mycobacterium tuberculosis.
Academic Article Bacterial growth and cell division: a mycobacterial perspective.
Academic Article Inhibition of bacterial disulfide bond formation by the anticoagulant warfarin.
Academic Article New genetic approaches shed light on TB virulence.
Academic Article Characterization of mycobacterial virulence genes through genetic interaction mapping.
Academic Article Nitrile-inducible gene expression in mycobacteria.
Concept Mycobacterium leprae
Concept Mycobacterium marinum
Concept Mycobacterium bovis
Concept Mycobacterium
Concept Mycobacterium smegmatis
Concept Mycobacterium Infections
Concept Mycobacterium tuberculosis
Concept Mycobacterium kansasii
Concept Mycobacterium fortuitum
Academic Article Diarylcoumarins inhibit mycolic acid biosynthesis and kill Mycobacterium tuberculosis by targeting FadD32.
Academic Article Bayesian analysis of gene essentiality based on sequencing of transposon insertion libraries.
Academic Article Letting sleeping dos lie: does dormancy play a role in tuberculosis?
Academic Article Genomic analysis identifies targets of convergent positive selection in drug-resistant Mycobacterium tuberculosis.
Academic Article A phosphorylated pseudokinase complex controls cell wall synthesis in mycobacteria.
Academic Article Detection and treatment of subclinical tuberculosis.
Academic Article The abyssomicin C family as in vitro inhibitors of Mycobacterium tuberculosis.
Academic Article Structural characterization of the Mycobacterium tuberculosis biotin biosynthesis enzymes 7,8-diaminopelargonic acid synthase and dethiobiotin synthetase .
Academic Article para-Aminosalicylic acid is a prodrug targeting dihydrofolate reductase in Mycobacterium tuberculosis.
Academic Article Clinical practice. Latent tuberculosis infection in the United States.
Academic Article Identification of new drug targets and resistance mechanisms in Mycobacterium tuberculosis.
Academic Article para-Aminosalicylic acid is a prodrug targeting dihydrofolate reductase in Mycobacterium tuberculosis.
Academic Article High-throughput sequencing enhanced phage display identifies peptides that bind mycobacteria.
Academic Article Tryptophan biosynthesis protects mycobacteria from CD4 T-cell-mediated killing.
Academic Article Mycobacterial mistranslation is necessary and sufficient for rifampicin phenotypic resistance.
Academic Article Metabolic and bactericidal effects of targeted suppression of NadD and NadE enzymes in mycobacteria.
Academic Article Molecular profiling of Mycobacterium tuberculosis identifies tuberculosinyl nucleoside products of the virulence-associated enzyme Rv3378c.
Academic Article Identification of host-targeted small molecules that restrict intracellular Mycobacterium tuberculosis growth.
Academic Article Post-translational regulation via Clp protease is critical for survival of Mycobacterium tuberculosis.
Academic Article Mycobacterial Esx-3 requires multiple components for iron acquisition.
Academic Article Mycobacterium tuberculosis FtsX extracellular domain activates the peptidoglycan hydrolase, RipC.
Academic Article How sisters grow apart: mycobacterial growth and division.
Academic Article Mycobacterial gene cuvA is required for optimal nutrient utilization and virulence.
Academic Article ARTIST: high-resolution genome-wide assessment of fitness using transposon-insertion sequencing.
Academic Article Compounds targeting disulfide bond forming enzyme DsbB of Gram-negative bacteria.
Academic Article Lipidomic analysis links mycobactin synthase K to iron uptake and virulence in M. tuberculosis.
Academic Article New insights into TB physiology suggest untapped therapeutic opportunities.
Academic Article A novel antimycobacterial compound acts as an intracellular iron chelator.
Academic Article Mycobacterial nicotinate mononucleotide adenylyltransferase: structure, mechanism, and implications for drug discovery.
Academic Article Cleavage Specificity of Mycobacterium tuberculosis ClpP1P2 Protease and Identification of Novel Peptide Substrates and Boronate Inhibitors with Anti-bacterial Activity.
Academic Article Binding of MgtR, a Salmonella transmembrane regulatory peptide, to MgtC, a Mycobacterium tuberculosis virulence factor: a structural study.
Academic Article Target mechanism-based whole-cell screening identifies bortezomib as an inhibitor of caseinolytic protease in mycobacteria.
Academic Article Phosphorylation of the Peptidoglycan Synthase PonA1 Governs the Rate of Polar Elongation in Mycobacteria.
Academic Article Benzoic Acid-Inducible Gene Expression in Mycobacteria.
Academic Article Peptidoglycan synthesis in Mycobacterium tuberculosis is organized into networks with varying drug susceptibility.
Academic Article Mycobacterial Metabolic Syndrome: LprG and Rv1410 Regulate Triacylglyceride Levels, Growth Rate and Virulence in Mycobacterium tuberculosis.
Academic Article Leveraging Advances in Tuberculosis Diagnosis and Treatment to Address Nontuberculous Mycobacterial Disease.
Academic Article Crystal structures of the transpeptidase domain of the Mycobacterium tuberculosis penicillin-binding protein PonA1 reveal potential mechanisms of antibiotic resistance.
Academic Article Could Killing Bacterial Subpopulations Hit Tuberculosis out of the Park?
Academic Article A cytoplasmic peptidoglycan amidase homologue controls mycobacterial cell wall synthesis.
Grant VIRULENCE FACTORS IN MYCOBACTERIA
Grant Virulence Factors in Mycobacteria
Grant Integrated discovery and development of innovative TB Diagnostics
Grant Drug Targets for Tuberculosis
Grant A Community Mycobacterial Systems Resource
Grant Decoding the roles of critical genes of unknown function in M. tuberculosis
Grant Drug resistance in tuberculosis: genetic and dynamics
Grant Structures of Mtb proteins conferring susceptibility to known Mtb inhibitors
Academic Article Comprehensive Essentiality Analysis of the Mycobacterium tuberculosis Genome via Saturating Transposon Mutagenesis.
Academic Article Programmable transcriptional repression in mycobacteria using an orthogonal CRISPR interference platform.
Academic Article Draft Genome Sequence of Mycobacterium abscessus Bamboo.
Academic Article Deletion of a mycobacterial divisome factor collapses single-cell phenotypic heterogeneity.
Academic Article Reviving a Drug for Tuberculosis?
Academic Article Development of a Novel Lead that Targets M. tuberculosis Polyketide Synthase 13.
Academic Article Draft Genome Sequence of Mycobacterium avium 11.
Academic Article A comprehensive characterization of PncA polymorphisms that confer resistance to pyrazinamide.
Academic Article An Antibacterial ß-Lactone Kills Mycobacterium tuberculosis by Disrupting Mycolic Acid Biosynthesis.
Academic Article Towards the use of breath for detecting mycobacterial infection: a case study in a murine model.
Academic Article Characterization of Conserved and Novel Septal Factors in Mycobacterium smegmatis.
Academic Article Identification of genes required for Mycobacterium abscessus growth in vivo with a prominent role of the ESX-4 locus.
Academic Article TB diagnosis from the Dark Ages to fluorescence.
Academic Article Kasugamycin potentiates rifampicin and limits emergence of resistance in Mycobacterium tuberculosis by specifically decreasing mycobacterial mistranslation.
Academic Article Maturing Mycobacterium smegmatis peptidoglycan requires non-canonical crosslinks to maintain shape.
Academic Article Inhibition of Pseudomonas aeruginosa and Mycobacterium tuberculosis disulfide bond forming enzymes.
Academic Article Cell Wall Hydrolytic Enzymes Enhance Antimicrobial Drug Activity Against Mycobacterium.
Grant Development of a Self Inactivating, Highly Effective TB Vaccine
Academic Article The Dream of a Mycobacterium.
Academic Article Mycobacterium smegmatis HtrA Blocks the Toxic Activity of a Putative Cell Wall Amidase.
Academic Article Large-scale chemical-genetics yields new M. tuberculosis inhibitor classes.
Academic Article Genome-wide Phenotypic Profiling Identifies and Categorizes Genes Required for Mycobacterial Low Iron Fitness.
Academic Article Mycobacterium tuberculosis releases an antacid that remodels phagosomes.
Academic Article Novel Pyrazole-Containing Compounds Active against Mycobacterium tuberculosis.
Academic Article Itaconyl-CoA forms a stable biradical in methylmalonyl-CoA mutase and derails its activity and repair.
Academic Article The mycobacterial cell envelope - a moving target.
Academic Article Global Assessment of Mycobacterium avium subsp. hominissuis Genetic Requirement for Growth and Virulence.
Academic Article Pyrazinamide triggers degradation of its target aspartate decarboxylase.
Academic Article Aspartate aminotransferase Rv3722c governs aspartate-dependent nitrogen metabolism in Mycobacterium tuberculosis.
Academic Article Nonredundant functions of Mycobacterium tuberculosis chaperones promote survival under stress.
Academic Article ClpX Is Essential and Activated by Single-Strand DNA Binding Protein in Mycobacteria.
Academic Article Protective efficacy of an attenuated Mtb ?LprG vaccine in mice.
Academic Article The conserved translation factor LepA is required for optimal synthesis of a porin family in Mycobacterium smegmatis.
Grant Using genetics and multi-scale imaging to understand the mechanisms underlying mycobacteriophage host choice
Academic Article Mycobacteriophages as Genomic Engineers and Anti-infective Weapons.
Academic Article 6-Fluorophenylbenzohydrazides inhibit Mycobacterium tuberculosis growth through alteration of tryptophan biosynthesis.
Search Criteria
  • Mycobacterium
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.