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One or more keywords matched the following items that are connected to Kahn, Barbara
Item TypeName
Academic Article Chronic free fatty acid infusion in rats results in insulin resistance but no alteration in insulin-responsive glucose transporter levels in skeletal muscle.
Academic Article Lilly lecture 1995. Glucose transport: pivotal step in insulin action.
Academic Article Divergent regulation of the Glut 1 and Glut 4 glucose transporters in isolated adipocytes from Zucker rats.
Academic Article Over-expression of GLUT4 selectively in adipose tissue in transgenic mice: implications for nutrient partitioning.
Academic Article Expression of the brain-type glucose transporter is restricted to brain and neuronal cells in mice.
Academic Article Models of insulin action on metabolic and growth response genes.
Academic Article Neuronal PTP1B regulates body weight, adiposity and leptin action.
Academic Article Human small intestine facilitative fructose/glucose transporter (GLUT5) is also present in insulin-responsive tissues and brain. Investigation of biochemical characteristics and translocation.
Academic Article Glucose toxicity and the development of diabetes in mice with muscle-specific inactivation of GLUT4.
Academic Article Effect of aging and obesity on insulin responsiveness and glut-4 glucose transporter content in skeletal muscle of Fischer 344 x Brown Norway rats.
Academic Article Alterations in glucose transporter expression and function in diabetes: mechanisms for insulin resistance.
Academic Article Adipose-specific overexpression of GLUT4 reverses insulin resistance and diabetes in mice lacking GLUT4 selectively in muscle.
Academic Article High fat feeding causes insulin resistance and a marked decrease in the expression of glucose transporters (Glut 4) in fat cells of rats.
Academic Article Insulin hypersensitivity and resistance to streptozotocin-induced diabetes in mice lacking PTEN in adipose tissue.
Academic Article High circulating levels of RBP4 and mRNA levels of aP2, PGC-1alpha and UCP-2 predict improvement in insulin sensitivity following pioglitazone treatment of drug-naïve type 2 diabetic subjects.
Academic Article Deletion of cd39/entpd1 results in hepatic insulin resistance.
Academic Article Amelioration of insulin resistance in streptozotocin diabetic mice by transgenic overexpression of GLUT4 driven by an adipose-specific promoter.
Academic Article Increased energy expenditure, decreased adiposity, and tissue-specific insulin sensitivity in protein-tyrosine phosphatase 1B-deficient mice.
Academic Article Tissue-specific nutritional regulation of angiotensinogen in adipose tissue.
Academic Article Facilitative glucose transporters: regulatory mechanisms and dysregulation in diabetes.
Academic Article Tissue-specific ablation of the GLUT4 glucose transporter or the insulin receptor challenges assumptions about insulin action and glucose homeostasis.
Academic Article Adipose tissue dysregulation and reduced insulin sensitivity in non-obese individuals with enlarged abdominal adipose cells.
Academic Article GLUT4 glucose transporter deficiency increases hepatic lipid production and peripheral lipid utilization.
Academic Article Subcellular translocation of glucose transporters: role in insulin action and its perturbation in altered metabolic states.
Academic Article Adenovirus-mediated gene transfer of dominant negative ras(asn17) in 3T3L1 adipocytes does not alter insulin-stimulated P13-kinase activity or glucose transport.
Academic Article Serum retinol-binding protein is more highly expressed in visceral than in subcutaneous adipose tissue and is a marker of intra-abdominal fat mass.
Academic Article aP2-Cre-mediated expression activation of an oncogenic PLAG1 transgene results in cavernous angiomatosis in mice.
Academic Article Neuronal protein tyrosine phosphatase 1B deficiency results in inhibition of hypothalamic AMPK and isoform-specific activation of AMPK in peripheral tissues.
Academic Article Adipose tissue branched chain amino acid (BCAA) metabolism modulates circulating BCAA levels.
Academic Article In vivo administration of leptin activates signal transduction directly in insulin-sensitive tissues: overlapping but distinct pathways from insulin.
Academic Article Divergent regulation of Akt1 and Akt2 isoforms in insulin target tissues of obese Zucker rats.
Academic Article Obesity and insulin resistance.
Academic Article Extended longevity in mice lacking the insulin receptor in adipose tissue.
Academic Article Effects of genetic variation in the human retinol binding protein-4 gene (RBP4) on insulin resistance and fat depot-specific mRNA expression.
Academic Article Adipose tissue selective insulin receptor knockout protects against obesity and obesity-related glucose intolerance.
Academic Article Adipose-specific overexpression of GLUT-4 in transgenic mice alters lipoprotein lipase activity.
Academic Article Increased insulin sensitivity and reduced adiposity in phosphatidylinositol 5-phosphate 4-kinase beta-/- mice.
Academic Article Divergent mechanisms for the insulin resistant and hyperresponsive glucose transport in adipose cells from fasted and refed rats. Alterations in both glucose transporter number and intrinsic activity.
Academic Article High level overexpression of glucose transporter-4 driven by an adipose-specific promoter is maintained in transgenic mice on a high fat diet, but does not prevent impaired glucose tolerance.
Academic Article A novel ChREBP isoform in adipose tissue regulates systemic glucose metabolism.
Academic Article Expression of ob mRNA and its encoded protein in rodents. Impact of nutrition and obesity.
Academic Article Leptin stimulates fatty acid oxidation directly in white adipose tissue through activation of AMP-activated protein kinase. Presented at the American Diabetes Association Annual Scientific Sessions
Academic Article Biology of adipose tissue. In Joslin’s Diabetes Mellitus. CR Kahn, GC Weir, GL King, AC Moses, RJ Smith, AM Jacobson eds
Academic Article Redistribution of substrates to adipose tissue promotes obesity in mice with selective insulin resistance in muscle.
Academic Article Normalization of blood glucose in diabetic rats with phlorizin treatment reverses insulin-resistant glucose transport in adipose cells without restoring glucose transporter gene expression.
Academic Article Tissue-specific regulation of glucose transporters in different forms of obesity.
Academic Article Cell biology of insulin's stimulatory action on glucose transport and its perturbation in altered metabolic states.
Academic Article Targeted disruption of the beta 3-adrenergic receptor gene.
Academic Article Mechanism for enhanced glucose transport response to insulin in adipose cells from chronically hyperinsulinemic rats. Increased translocation of glucose transporters from an enlarged intracellular pool.
Academic Article Lessons on conditional gene targeting in mouse adipose tissue.
Academic Article Adipocyte/macrophage fatty acid binding proteins control integrated metabolic responses in obesity and diabetes.
Academic Article GLUT4, AMP kinase, but not the insulin receptor, are required for hepatoportal glucose sensor-stimulated muscle glucose utilization.
Academic Article Protein kinase C isoforms epsilon, eta, delta and zeta in murine adipocytes: expression, subcellular localization and tissue-specific regulation in insulin-resistant states.
Academic Article Adrenergic regulation of AMP-activated protein kinase in brown adipose tissue in vivo.
Academic Article Nutrient sensor links obesity with diabetes risk.
Academic Article The adipokine lipocalin 2 is regulated by obesity and promotes insulin resistance.
Academic Article Overexpression of Glut4 in adipose tissue “rescues” insulin resistance and glucose intolerance in muscle-specific Glut4 knockout mice. Presented at the Keystone conference on Diabetes Mellitus: Molecular Mechanisms, Genetics and New Therapies. Keystone, CO
Academic Article Transgenic GLUT-4 overexpression in fat enhances glucose metabolism: preferential effect on fatty acid synthesis.
Academic Article Glut4 is targeted to specific vesicles in adipocytes of transgenic mice overexpressing Glut4 selectively in adipose tissue.
Academic Article Overexpression of Ha-ras selectively in adipose tissue of transgenic mice. Evidence for enhanced sensitivity to insulin.
Academic Article Intrinsic heterogeneity in adipose tissue of fat-specific insulin receptor knock-out mice is associated with differences in patterns of gene expression.
Academic Article Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes.
Academic Article Suppression of GLUT4 expression in skeletal muscle of rats that are obese from high fat feeding but not from high carbohydrate feeding or genetic obesity.
Academic Article Glucose transport in adipose tissue is essential for the acute effect of â3 adrenergic agonists on glucose homeostasis. Presented at the American Diabetes Association Annual Scientific Sessions
Academic Article Adipose cell hyperplasia and enhanced glucose disposal in transgenic mice overexpressing GLUT4 selectively in adipose tissue.
Academic Article Mechanism for markedly hyperresponsive insulin-stimulated glucose transport activity in adipose cells from insulin-treated streptozotocin diabetic rats. Evidence for increased glucose transporter intrinsic activity.
Academic Article Divergent molecular mechanisms for insulin-resistant glucose transport in muscle and adipose cells in vivo.
Academic Article Differential regulation of two glucose transporters in adipose cells from diabetic and insulin-treated diabetic rats.
Academic Article Regulation of glucose transporter-specific mRNA levels in rat adipose cells with fasting and refeeding. Implications for in vivo control of glucose transporter number.
Academic Article Dietary regulation of glucose transporter gene expression: tissue specific effects in adipose cells and muscle.
Concept Adipose Tissue, Brown
Concept Adipose Tissue, White
Concept Adipose Tissue
Academic Article Downregulation of STRA6 in adipocytes and adipose stromovascular fraction in obesity and effects of adipocyte-specific STRA6 knockdown in vivo.
Academic Article Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity.
Academic Article RBP4 activates antigen-presenting cells, leading to adipose tissue inflammation and systemic insulin resistance.
Academic Article Discovery of a class of endogenous mammalian lipids with anti-diabetic and anti-inflammatory effects.
Academic Article Transthyretin Antisense Oligonucleotides Lower Circulating RBP4 Levels and Improve Insulin Sensitivity in Obese Mice.
Academic Article Leptin and insulin act on POMC neurons to promote the browning of white fat.
Academic Article Antigen Presentation and T-Cell Activation Are Critical for RBP4-Induced Insulin Resistance.
Academic Article GLUT4 Expression in Adipocytes Regulates De Novo Lipogenesis and Levels of a Novel Class of Lipids With Antidiabetic and Anti-inflammatory Effects.
Academic Article Adipose tissue regulates insulin sensitivity: role of adipogenesis, de novo lipogenesis and novel lipids.
Academic Article Adipocyte-specific overexpression of retinol-binding protein 4 causes hepatic steatosis in mice.
Academic Article Overexpressing the novel autocrine/endocrine adipokine WISP2 induces hyperplasia of the heart, white and brown adipose tissues and prevents insulin resistance.
Academic Article Stereochemistry of Endogenous Palmitic Acid Ester of 9-Hydroxystearic Acid and Relevance of Absolute Configuration to Regulation.
Academic Article Brown Adipose Tissue Controls Skeletal Muscle Function via the Secretion of Myostatin.
Academic Article Adipose tissue dysfunction is associated with low levels of the novel Palmitic Acid Hydroxystearic Acids.
Academic Article Adipose Tissue, Inter-Organ Communication, and the Path to Type 2 Diabetes: The 2016 Banting Medal for Scientific Achievement Lecture.
Academic Article Discovery of FAHFA-Containing Triacylglycerols and Their Metabolic Regulation.
Academic Article PAHSAs enhance hepatic and systemic insulin sensitivity through direct and indirect mechanisms.
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  • Adipose Tissue
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.