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Item TypeName
Academic Article Escape and compensation from early HLA-B57-mediated cytotoxic T-lymphocyte pressure on human immunodeficiency virus type 1 Gag alter capsid interactions with cyclophilin A.
Academic Article HLA footprints on human immunodeficiency virus type 1 are associated with interclade polymorphisms and intraclade phylogenetic clustering.
Academic Article HIV-1 viral escape in infancy followed by emergence of a variant-specific CTL response.
Academic Article Control of human immunodeficiency virus replication by cytotoxic T lymphocytes targeting subdominant epitopes.
Academic Article Immune-driven recombination and loss of control after HIV superinfection.
Academic Article Design, expression, and processing of epitomized hepatitis C virus-encoded CTL epitopes.
Academic Article Rapid evolution of HIV-1 to functional CD8? T cell responses in humanized BLT mice.
Academic Article The majority of currently circulating human immunodeficiency virus type 1 clade B viruses fail to prime cytotoxic T-lymphocyte responses against an otherwise immunodominant HLA-A2-restricted epitope: implications for vaccine design.
Academic Article Compensatory mutations restore the replication defects caused by cytotoxic T lymphocyte escape mutations in hepatitis C virus polymerase.
Academic Article Maternal transmission of human immunodeficiency virus escape mutations subverts HLA-B57 immunodominance but facilitates viral control in the haploidentical infant.
Academic Article TCR clonotypes modulate the protective effect of HLA class I molecules in HIV-1 infection.
Academic Article De novo generation of escape variant-specific CD8+ T-cell responses following cytotoxic T-lymphocyte escape in chronic human immunodeficiency virus type 1 infection.
Academic Article Structural and functional constraints limit options for cytotoxic T-lymphocyte escape in the immunodominant HLA-B27-restricted epitope in human immunodeficiency virus type 1 capsid.
Academic Article HLA-B57/B*5801 human immunodeficiency virus type 1 elite controllers select for rare gag variants associated with reduced viral replication capacity and strong cytotoxic T-lymphocyte [corrected] recognition.
Academic Article Adaptation of HIV-1 to human leukocyte antigen class I.
Academic Article A viral CTL escape mutation leading to immunoglobulin-like transcript 4-mediated functional inhibition of myelomonocytic cells.
Academic Article Marked epitope- and allele-specific differences in rates of mutation in human immunodeficiency type 1 (HIV-1) Gag, Pol, and Nef cytotoxic T-lymphocyte epitopes in acute/early HIV-1 infection.
Academic Article Broad repertoire of the CD4+ Th cell response in spontaneously controlled hepatitis C virus infection includes dominant and highly promiscuous epitopes.
Academic Article HIV evolution: CTL escape mutation and reversion after transmission.
Academic Article Escape from the dominant HLA-B27-restricted cytotoxic T-lymphocyte response in Gag is associated with a dramatic reduction in human immunodeficiency virus type 1 replication.
Academic Article Protective HLA class I alleles that restrict acute-phase CD8+ T-cell responses are associated with viral escape mutations located in highly conserved regions of human immunodeficiency virus type 1.
Academic Article Differential neutralization of human immunodeficiency virus (HIV) replication in autologous CD4 T cells by HIV-specific cytotoxic T lymphocytes.
Academic Article Early selection in Gag by protective HLA alleles contributes to reduced HIV-1 replication capacity that may be largely compensated for in chronic infection.
Academic Article Spontaneous control of HCV is associated with expression of HLA-B 57 and preservation of targeted epitopes.
Academic Article Protective effect of human leukocyte antigen B27 in hepatitis C virus infection requires the presence of a genotype-specific immunodominant CD8+ T-cell epitope.
Academic Article CD8 epitope escape and reversion in acute HCV infection.
Academic Article Influence of HLA-B57 on clinical presentation and viral control during acute HIV-1 infection.
Academic Article Selection, transmission, and reversion of an antigen-processing cytotoxic T-lymphocyte escape mutation in human immunodeficiency virus type 1 infection.
Academic Article Effects of thymic selection of the T-cell repertoire on HLA class I-associated control of HIV infection.
Academic Article Viral sequence evolution in acute hepatitis C virus infection.
Academic Article A novel immunodominant CD8+ T cell response restricted by a common HLA-C allele targets a conserved region of Gag HIV-1 clade CRF01_AE infected Thais.
Academic Article Human leukocyte antigen B27 selects for rare escape mutations that significantly impair hepatitis C virus replication and require compensatory mutations.
Academic Article Gorillas with spondyloarthropathies express an MHC class I molecule with only limited sequence similarity to HLA-B27 that binds peptides with arginine at P2.
Academic Article Vaccine-induced CD8+ T cells control AIDS virus replication.
Academic Article Differences in the expressed HLA class I alleles effect the differential clustering of HIV type 1-specific T cell responses in infected Chinese and caucasians.
Academic Article High resolution analysis of cellular immune responses in resolved and persistent hepatitis C virus infection.
Academic Article HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8(+) T Cell Response against HIV-1.
Academic Article Differential natural killer cell-mediated inhibition of HIV-1 replication based on distinct KIR/HLA subtypes.
Academic Article Contribution of immunological and virological factors to extremely severe primary HIV type 1 infection.
Academic Article HLA-associated alterations in replication capacity of chimeric NL4-3 viruses carrying gag-protease from elite controllers of human immunodeficiency virus type 1.
Academic Article Escape from a dominant HLA-B*15-restricted CD8+ T cell response against hepatitis C virus requires compensatory mutations outside the epitope.
Academic Article Virological and immunological determinants of intrahepatic virus-specific CD8+ T-cell failure in chronic hepatitis C virus infection.
Academic Article Dominant influence of HLA-B in mediating the potential co-evolution of HIV and HLA.
Academic Article A high incidence of Shigella-induced arthritis in a primate species: major histocompatibility complex class I molecules associated with resistance and susceptibility, and their relationship to HLA-B27.
Academic Article Mutually exclusive T-cell receptor induction and differential susceptibility to human immunodeficiency virus type 1 mutational escape associated with a two-amino-acid difference between HLA class I subtypes.
Academic Article The major genetic determinants of HIV-1 control affect HLA class I peptide presentation.
Academic Article HLA-B63 presents HLA-B57/B58-restricted cytotoxic T-lymphocyte epitopes and is associated with low human immunodeficiency virus load.
Concept HLA Antigens
Concept HLA-B Antigens
Concept HLA-A Antigens
Concept HLA-A3 Antigen
Concept HLA-DR Antigens
Concept HLA-B35 Antigen
Concept HLA-A2 Antigen
Concept HLA-B8 Antigen
Concept HLA-B27 Antigen
Concept HLA-C Antigens
Academic Article HLA-B*27 subtype specificity determines targeting and viral evolution of a hepatitis C virus-specific CD8+ T cell epitope.
Academic Article Temporal effect of HLA-B*57 on viral control during primary HIV-1 infection.
Academic Article How a single patient influenced HIV research--15-year follow-up.
Academic Article Increased frequency and function of KIR2DL1-3? NK cells in primary HIV-1 infection are determined by HLA-C group haplotypes.
Academic Article HIV Minor Variants Detected by Next Generation Sequencing: Impact on Immune Control of HIV in the Context of HLA-B*27:05 and HLA-B*57:01.
Academic Article Disease progression despite protective HLA expression in an HIV-infected transmission pair.
Academic Article Vaccine-Induced Simian Immunodeficiency Virus-Specific CD8+ T-Cell Responses Focused on a Single Nef Epitope Select for Escape Variants Shortly after Infection.
Academic Article Distinct Escape Pathway by Hepatitis C Virus Genotype 1a from a Dominant CD8+ T Cell Response by Selection of Altered Epitope Processing.
Grant Impact of CTL Escape Mutations on HIV-1 Replicative Fitness
Grant Acute HIV Infection: Implications for vaccine design
Grant Wisconsin National Primate Research Center Support
Grant Impact of CD8 Escape Mutations on Capsid Structure/Host
Grant Protective Role of Subdominant Responses to HIV Restricted by Common HLA Alleles
Grant CD8 T Cell Selective Pressure and HCV Sequence Evolution
Grant Impact of NK Cell Immune Pressures on HCV Evolution and Viral Fitness
Academic Article Antiviral CD8+ T Cells Restricted by Human Leukocyte Antigen Class II Exist during Natural HIV Infection and Exhibit Clonal Expansion.
Academic Article Rapid HIV disease progression following superinfection in an HLA-B*27:05/B*57:01-positive transmission recipient.
Academic Article Structural topology defines protective CD8+ T cell epitopes in the HIV proteome.
Search Criteria
  • HLA A Antigens
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.