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One or more keywords matched the following items that are connected to Kelly, Daniel
Item TypeName
Academic Article Cardiac-specific overexpression of peroxisome proliferator-activated receptor-alpha causes insulin resistance in heart and liver.
Academic Article Peroxisome proliferator-activated receptor coactivator-1alpha (PGC-1alpha) coactivates the cardiac-enriched nuclear receptors estrogen-related receptor-alpha and -gamma. Identification of novel leucine-rich interaction motif within PGC-1alpha.
Academic Article Calcineurin and calcium/calmodulin-dependent protein kinase activate distinct metabolic gene regulatory programs in cardiac muscle.
Academic Article Chronic activation of PPARalpha is detrimental to cardiac recovery after ischemia.
Academic Article The cardiac phenotype induced by PPARalpha overexpression mimics that caused by diabetes mellitus.
Academic Article Peroxisome proliferator-activated receptor alpha (PPARalpha) signaling in the gene regulatory control of energy metabolism in the normal and diseased heart.
Academic Article Rescue of cardiomyopathy in peroxisome proliferator-activated receptor-alpha transgenic mice by deletion of lipoprotein lipase identifies sources of cardiac lipids and peroxisome proliferator-activated receptor-alpha activators.
Academic Article A role for peroxisome proliferator-activated receptor alpha (PPARalpha ) in the control of cardiac malonyl-CoA levels: reduced fatty acid oxidation rates and increased glucose oxidation rates in the hearts of mice lacking PPARalpha are associated with higher concentrations of malonyl-CoA and reduced expression of malonyl-CoA decarboxylase.
Academic Article The transcriptional coactivator PGC-1alpha is essential for maximal and efficient cardiac mitochondrial fatty acid oxidation and lipid homeostasis.
Academic Article Peroxisome proliferator-activated receptor alpha as a genetic determinant of cardiac hypertrophic growth: culprit or innocent bystander?
Academic Article Nuclear receptors PPARbeta/delta and PPARalpha direct distinct metabolic regulatory programs in the mouse heart.
Academic Article Impaired contractile function and calcium handling in hearts of cardiac-specific calcineurin b1-deficient mice.
Academic Article Decreased contractile and metabolic reserve in peroxisome proliferator-activated receptor-alpha-null hearts can be rescued by increasing glucose transport and utilization.
Academic Article Toll-like receptor-mediated inflammatory signaling reprograms cardiac energy metabolism by repressing peroxisome proliferator-activated receptor ? coactivator-1 signaling.
Academic Article Preferential oxidation of triacylglyceride-derived fatty acids in heart is augmented by the nuclear receptor PPARalpha.
Academic Article PPARalpha-mediated remodeling of repolarizing voltage-gated K+ (Kv) channels in a mouse model of metabolic cardiomyopathy.
Academic Article Chronic inhibition of pyruvate dehydrogenase in heart triggers an adaptive metabolic response.
Academic Article Estrogen-related receptor alpha directs peroxisome proliferator-activated receptor alpha signaling in the transcriptional control of energy metabolism in cardiac and skeletal muscle.
Concept Myocardium
Academic Article A critical role for PPARalpha-mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: modulation by dietary fat content.
Academic Article Signalling in cardiac metabolism.
Academic Article PPARs of the heart: three is a crowd.
Academic Article Nuclear receptor signaling and cardiac energetics.
Academic Article Retinoid X receptor alpha represses GATA-4-mediated transcription via a retinoid-dependent interaction with the cardiac-enriched repressor FOG-2.
Academic Article Mitochondrial energy metabolism in heart failure: a question of balance.
Academic Article The PPAR trio: regulators of myocardial energy metabolism in health and disease.
Academic Article Myocardial fatty acid metabolism: independent predictor of left ventricular mass in hypertensive heart disease.
Academic Article The PGC-1 cascade as a therapeutic target for heart failure.
Academic Article Altered myocardial fatty acid and glucose metabolism in idiopathic dilated cardiomyopathy.
Grant Membrane-Mediated Alterations in Diabetes
Academic Article Mitochondrial biogenesis and dynamics in the developing and diseased heart.
Academic Article Parkin-mediated mitophagy directs perinatal cardiac metabolic maturation in mice.
Academic Article Cardiac nuclear receptors: architects of mitochondrial structure and function.
Academic Article Molecular Mechanisms Underlying Cardiac Adaptation to Exercise.
Academic Article The failing heart utilizes 3-hydroxybutyrate as a metabolic stress defense.
Academic Article Increased ketone body oxidation provides additional energy for the failing heart without improving cardiac efficiency.
Academic Article Mitochondrial calcium exchange links metabolism with the epigenome to control cellular differentiation.
Academic Article Fueling Cardiac Hypertrophy.
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  • Myocardium
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.