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One or more keywords matched the following items that are connected to Spiegelman, Bruce
Item TypeName
Academic Article Suppression of mitochondrial respiration through recruitment of p160 myb binding protein to PGC-1alpha: modulation by p38 MAPK.
Academic Article A synthetic antagonist for the peroxisome proliferator-activated receptor gamma inhibits adipocyte differentiation.
Academic Article Inhibition of adipogenesis through MAP kinase-mediated phosphorylation of PPARgamma.
Academic Article Activation of PPARgamma coactivator-1 through transcription factor docking.
Academic Article ADD1/SREBP1 activates PPARgamma through the production of endogenous ligand.
Academic Article Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1.
Academic Article Regulation of adipogenesis and energy balance by PPARgamma and PGC-1.
Academic Article Adipocyte differentiation: a transcriptional regulatory cascade.
Academic Article An adipogenic cofactor bound by the differentiation domain of PPARgamma.
Academic Article A direct role for c-fos in AP-1-dependent gene transcription.
Academic Article A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis.
Academic Article Transcriptional regulation of adipogenesis.
Academic Article Identification of novel genes involved in adipose differentiation by differential display.
Academic Article Adipocytes as regulators of energy balance and glucose homeostasis.
Academic Article AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha.
Academic Article Transducer of regulated CREB-binding proteins (TORCs) induce PGC-1alpha transcription and mitochondrial biogenesis in muscle cells.
Academic Article Induction of solid tumor differentiation by the peroxisome proliferator-activated receptor-gamma ligand troglitazone in patients with liposarcoma.
Academic Article Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1.
Academic Article Modulation of estrogen receptor-alpha transcriptional activity by the coactivator PGC-1.
Academic Article Transcriptional control of brown fat determination by PRDM16.
Academic Article Antidiabetic actions of a non-agonist PPAR? ligand blocking Cdk5-mediated phosphorylation.
Academic Article Disorder-to-order transition underlies the structural basis for the assembly of a transcriptionally active PGC-1a/ERR? complex.
Academic Article Regulation of adipocyte gene expression and differentiation by peroxisome proliferator activated receptor gamma.
Academic Article Yeast GCN4 as a probe for oncogenesis by AP-1 transcription factors: transcriptional activation through AP-1 sites is not sufficient for cellular transformation.
Academic Article Molecular regulation of adipogenesis.
Academic Article Biological control through regulated transcriptional coactivators.
Academic Article A fat-specific enhancer is the primary determinant of gene expression for adipocyte P2 in vivo.
Academic Article Cytokine stimulation of energy expenditure through p38 MAP kinase activation of PPARgamma coactivator-1.
Academic Article Erralpha and Gabpa/b specify PGC-1alpha-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle.
Academic Article Transcriptional control of mitochondrial energy metabolism through the PGC1 coactivators.
Academic Article Severely impaired adipsin expression in genetic and acquired obesity.
Academic Article PPAR gamma 2 regulates adipose expression of the phosphoenolpyruvate carboxykinase gene.
Academic Article 15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma.
Academic Article Transcriptional activation of adipogenesis.
Academic Article Regulation of gene expression of catecholamine biosynthetic enzymes by stress.
Academic Article Fatty acid regulation of gene expression. Transcriptional and post-transcriptional mechanisms.
Academic Article Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres.
Academic Article A direct role for C/EBP and the AP-I-binding site in gene expression linked to adipocyte differentiation.
Academic Article PGC-1alpha protects skeletal muscle from atrophy by suppressing FoxO3 action and atrophy-specific gene transcription.
Academic Article Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex.
Academic Article PAX8-PPARgamma1 fusion oncogene in human thyroid carcinoma [corrected].
Academic Article The unfolded protein response mediates adaptation to exercise in skeletal muscle through a PGC-1a/ATF6a complex.
Academic Article The transcriptional coactivator PGC-1beta drives the formation of oxidative type IIX fibers in skeletal muscle.
Academic Article PPAR{delta} agonism activates fatty acid oxidation via PGC-1{alpha} but does not increase mitochondrial gene expression and function.
Academic Article PGC-1alpha regulates a HIF2alpha-dependent switch in skeletal muscle fiber types.
Academic Article p38 mitogen-activated protein kinase is the central regulator of cyclic AMP-dependent transcription of the brown fat uncoupling protein 1 gene.
Academic Article Adipsin: a circulating serine protease homolog secreted by adipose tissue and sciatic nerve.
Academic Article Towards a molecular understanding of adaptive thermogenesis.
Academic Article Transcription coactivator TRAP220 is required for PPAR gamma 2-stimulated adipogenesis.
Academic Article Genetic analysis of adipogenesis through peroxisome proliferator-activated receptor gamma isoforms.
Academic Article Regulation of PPAR gamma gene expression by nutrition and obesity in rodents.
Academic Article Coordination of p300-mediated chromatin remodeling and TRAP/mediator function through coactivator PGC-1alpha.
Academic Article Transcriptional control of energy homeostasis through the PGC1 coactivators.
Concept Transcription, Genetic
Academic Article ß-Aminoisobutyric acid induces browning of white fat and hepatic ß-oxidation and is inversely correlated with cardiometabolic risk factors.
Academic Article Brown and Beige Fat: Molecular Parts of a Thermogenic Machine.
Search Criteria
  • Transcription Genetic
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.