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Item TypeName
Mentoring - Completed Student Project Assessing PRDM16 Protein Stability in Adipose Tissue
Academic Article Adipogenesis and obesity: rounding out the big picture.
Academic Article Uncoupling of obesity from insulin resistance through a targeted mutation in aP2, the adipocyte fatty acid binding protein.
Academic Article Analysis of a tissue-specific enhancer: ARF6 regulates adipogenic gene expression.
Academic Article ADD1/SREBP1 activates PPARgamma through the production of endogenous ligand.
Academic Article Cross-regulation of C/EBP alpha and PPAR gamma controls the transcriptional pathway of adipogenesis and insulin sensitivity.
Academic Article Adipose tissue reduction in mice lacking the translational inhibitor 4E-BP1.
Academic Article Regulation of adipogenesis and energy balance by PPARgamma and PGC-1.
Academic Article Identification of a fat cell enhancer: analysis of requirements for adipose tissue-specific gene expression.
Academic Article PPAR gamma is required for the differentiation of adipose tissue in vivo and in vitro.
Academic Article Differential regulation of the p80 tumor necrosis factor receptor in human obesity and insulin resistance.
Academic Article Transgenic mice overexpressing the beta 1-adrenergic receptor in adipose tissue are resistant to obesity.
Academic Article Vascular endothelial growth factor. Regulation by cell differentiation and activated second messenger pathways.
Academic Article Control of the adipsin gene in adipocyte differentiation. Identification of distinct nuclear factors binding to single- and double-stranded DNA.
Academic Article A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis.
Academic Article Transcriptional regulation of adipogenesis.
Academic Article Identification of novel genes involved in adipose differentiation by differential display.
Academic Article Regulation of alternative pathway activation and C3a production by adipose cells.
Academic Article Targeted expression of Cre recombinase to adipose tissue of transgenic mice directs adipose-specific excision of loxP-flanked gene segments.
Academic Article Reduced adipsin mRNA and circulating adipsin protein are modulated by adrenal steroids in obese Zucker rats.
Academic Article Heparin potentiation of 3T3-adipocyte stimulated angiogenesis: mechanisms of action on endothelial cells.
Academic Article Regulation of gene expression in the adipocyte: implications for obesity and proto-oncogene function.
Academic Article Dual DNA binding specificity of ADD1/SREBP1 controlled by a single amino acid in the basic helix-loop-helix domain.
Academic Article Biosynthesis of the vasoactive lipid monobutyrin. Central role of diacylglycerol.
Academic Article Transcriptional control of brown fat determination by PRDM16.
Academic Article Transcriptional control of brown adipocyte development and physiological function--of mice and men.
Academic Article Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARgamma by Cdk5.
Academic Article Decreases in tubulin and actin gene expression prior to morphological differentiation of 3T3 adipocytes.
Academic Article Human adipsin is identical to complement factor D and is expressed at high levels in adipose tissue.
Academic Article Antidiabetic actions of a non-agonist PPAR? ligand blocking Cdk5-mediated phosphorylation.
Academic Article FGF21 regulates PGC-1a and browning of white adipose tissues in adaptive thermogenesis.
Academic Article Beige adipocytes are a distinct type of thermogenic fat cell in mouse and human.
Academic Article The orphan nuclear receptor SHP regulates PGC-1alpha expression and energy production in brown adipocytes.
Academic Article Characterization of the novel brown adipocyte cell line HIB 1B. Adrenergic pathways involved in regulation of uncoupling protein gene expression.
Academic Article Peroxisome proliferator-activated receptor gamma target gene encoding a novel angiopoietin-related protein associated with adipose differentiation.
Academic Article Molecular regulation of adipogenesis.
Academic Article Adipsin and an endogenous pathway of complement from adipose cells.
Academic Article A fat-specific enhancer is the primary determinant of gene expression for adipocyte P2 in vivo.
Academic Article QnAs with Bruce M. Spiegelman.
Academic Article Fibronectin modulation of cell shape and lipogenic gene expression in 3T3-adipocytes.
Academic Article Independent regulation of adipose tissue-specificity and obesity response of the adipsin promoter in transgenic mice.
Academic Article Analysis of a tissue-specific enhancer: ARF6 regulates adipogenic gene expression.
Academic Article Identification of a potent adipocyte-specific enhancer: involvement of an NF-1-like factor.
Academic Article Insulin stimulates the acute release of adipsin from 3T3-L1 adipocytes.
Academic Article PPAR? agonists induce a white-to-brown fat conversion through stabilization of PRDM16 protein.
Academic Article TRPV4 is a regulator of adipose oxidative metabolism, inflammation, and energy homeostasis.
Academic Article Separation of simian virus 40 large-T-antigen-transforming and origin-binding functions from the ability to block differentiation.
Academic Article A PGC1-a-dependent myokine that drives brown-fat-like development of white fat and thermogenesis.
Academic Article A developmentally regulated mRNA from 3T3 adipocytes encodes a novel serine protease homologue.
Academic Article Transgenic mouse models of disease: altering adipose tissue function in vivo.
Academic Article Involvement of fos as a trans-acting factor in adipogenic gene expression.
Academic Article Abnormal glucose homeostasis in skeletal muscle-specific PGC-1alpha knockout mice reveals skeletal muscle-pancreatic beta cell crosstalk.
Academic Article Development of insulin resistance in mice lacking PGC-1a in adipose tissues.
Academic Article Severely impaired adipsin expression in genetic and acquired obesity.
Academic Article Adipsin and complement factor D activity: an immune-related defect in obesity.
Academic Article Transcriptional activation of adipogenesis.
Academic Article Biosynthetic regulation of monobutyrin, an adipocyte-secreted lipid with angiogenic activity.
Academic Article Peroxisome proliferator-activated receptor gamma and the control of adipogenesis.
Academic Article Nucleotide sequence and hormonal regulation of mouse glycerophosphate dehydrogenase mRNA during adipocyte and muscle cell differentiation.
Academic Article Peroxisome proliferator-activated receptor gamma: A key regulator of adipogenesis and systemic insulin sensitivity.
Academic Article Adipose expression of the phosphoenolpyruvate carboxykinase promoter requires peroxisome proliferator-activated receptor gamma and 9-cis-retinoic acid receptor binding to an adipocyte-specific enhancer in vivo.
Academic Article Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance.
Academic Article Targeted expression of a toxin gene to adipose tissue: transgenic mice resistant to obesity.
Academic Article Hibernoma formation in transgenic mice and isolation of a brown adipocyte cell line expressing the uncoupling protein gene.
Academic Article PPAR-gamma: adipogenic regulator and thiazolidinedione receptor.
Academic Article 1-Butyryl-glycerol: a novel angiogenesis factor secreted by differentiating adipocytes.
Academic Article A direct role for C/EBP and the AP-I-binding site in gene expression linked to adipocyte differentiation.
Academic Article Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice.
Academic Article PRDM16 controls a brown fat/skeletal muscle switch.
Academic Article Cyclic AMP-mediated control of lipogenic enzyme synthesis during adipose differentiation of 3T3 cells.
Academic Article Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex.
Academic Article Transcriptional control of preadipocyte determination by Zfp423.
Academic Article Recombinant retroviruses that transduce individual polyoma tumor antigens: effects on growth and differentiation.
Academic Article Transcriptional control of brown fat development.
Academic Article Common DNA binding site for Fos protein complexes and transcription factor AP-1.
Academic Article Regulation of gene expression during the differentiation of 3T3-adipocytes.
Academic Article Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance.
Academic Article Expression of the mitochondrial uncoupling protein gene from the aP2 gene promoter prevents genetic obesity.
Academic Article Sensitivity of lipid metabolism and insulin signaling to genetic alterations in hepatic peroxisome proliferator-activated receptor-gamma coactivator-1alpha expression.
Academic Article ADD1: a novel helix-loop-helix transcription factor associated with adipocyte determination and differentiation.
Academic Article Developmentally regulated mRNAs in 3T3-adipocytes: analysis of transcriptional control.
Academic Article Transdifferentiation of myoblasts by the adipogenic transcription factors PPAR gamma and C/EBP alpha.
Academic Article Initiation of myoblast to brown fat switch by a PRDM16-C/EBP-beta transcriptional complex.
Academic Article Molecular mechanisms of cancer development in obesity.
Academic Article Adaptive thermogenesis in adipocytes: is beige the new brown?
Academic Article Adipocyte P2 gene: developmental expression and homology of 5'-flanking sequences among fat cell-specific genes.
Academic Article p38 mitogen-activated protein kinase is the central regulator of cyclic AMP-dependent transcription of the brown fat uncoupling protein 1 gene.
Academic Article Potent stimulation of vascular endothelial cell growth by differentiated 3T3 adipocytes.
Academic Article IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance.
Academic Article Modulation of PGC-1 coactivator pathways in brown fat differentiation through LRP130.
Academic Article Adipsin, the adipocyte serine protease: gene structure and control of expression by tumor necrosis factor.
Academic Article Adipsin: a circulating serine protease homolog secreted by adipose tissue and sciatic nerve.
Academic Article Reduced tyrosine kinase activity of the insulin receptor in obesity-diabetes. Central role of tumor necrosis factor-alpha.
Academic Article Towards a molecular understanding of adaptive thermogenesis.
Academic Article Adipocyte-specific transcription factor ARF6 is a heterodimeric complex of two nuclear hormone receptors, PPAR gamma and RXR alpha.
Academic Article Transcription coactivator TRAP220 is required for PPAR gamma 2-stimulated adipogenesis.
Academic Article Tumor necrosis factor alpha: a key component of the obesity-diabetes link.
Academic Article Differential activation of adipogenesis by multiple PPAR isoforms.
Academic Article Regulation of PPAR gamma gene expression by nutrition and obesity in rodents.
Academic Article Complementary action of the PGC-1 coactivators in mitochondrial biogenesis and brown fat differentiation.
Academic Article Molecular cloning of mRNA from 3T3 adipocytes. Regulation of mRNA content for glycerophosphate dehydrogenase and other differentiation-dependent proteins during adipocyte development.
Academic Article Reduced adipsin expression in murine obesity: effect of age and treatment with the sympathomimetic-thermogenic drug mixture ephedrine and caffeine.
Academic Article Targeting of nonexpressed genes in embryonic stem cells via homologous recombination.
Academic Article fos protooncogene and the regulation of gene expression in adipocyte differentiation.
Academic Article Regulation of adipocyte gene expression in differentiation and syndromes of obesity/diabetes.
Academic Article Muscle-specific PPARgamma-deficient mice develop increased adiposity and insulin resistance but respond to thiazolidinediones.
Academic Article Adrenal glucocorticoids regulate adipsin gene expression in genetically obese mice.
Academic Article Nucleoprotein complexes that regulate gene expression in adipocyte differentiation: direct participation of c-fos.
Academic Article Control of specific protein biosynthesis during the adipose conversion of 3T3 cells.
Concept Adipose Tissue, Brown
Concept Adipose Tissue, White
Concept Adipose Tissue
Academic Article Banting Lecture 2012: Regulation of adipogenesis: toward new therapeutics for metabolic disease.
Academic Article ß-Aminoisobutyric acid induces browning of white fat and hepatic ß-oxidation and is inversely correlated with cardiometabolic risk factors.
Academic Article Ablation of PRDM16 and beige adipose causes metabolic dysfunction and a subcutaneous to visceral fat switch.
Academic Article A smooth muscle-like origin for beige adipocytes.
Academic Article Meteorin-like is a hormone that regulates immune-adipose interactions to increase beige fat thermogenesis.
Academic Article Adipsin is an adipokine that improves ß cell function in diabetes.
Academic Article IRF4 is a key thermogenic transcriptional partner of PGC-1a.
Academic Article Tumour-derived PTH-related protein triggers adipose tissue browning and cancer cachexia.
Academic Article An ERK/Cdk5 axis controls the diabetogenic actions of PPAR?.
Academic Article Appearance and disappearance of the mRNA signature characteristic of Treg cells in visceral adipose tissue: age, diet, and PPAR? effects.
Academic Article Brown and Beige Fat: Molecular Parts of a Thermogenic Machine.
Academic Article The future of brown adipose tissues in the treatment of type 2 diabetes.
Academic Article Brown and Beige Fat: Physiological Roles beyond Heat Generation.
Academic Article A creatine-driven substrate cycle enhances energy expenditure and thermogenesis in beige fat.
Academic Article A Secreted Slit2 Fragment Regulates Adipose Tissue Thermogenesis and Metabolic Function.
Academic Article PTH/PTHrP Receptor Mediates Cachexia in Models of Kidney Failure and Cancer.
Academic Article Mitochondrial ROS regulate thermogenic energy expenditure and sulfenylation of UCP1.
Academic Article Cell biology of fat storage.
Grant REGULATION OF MAMMALIAN PREADIPOCYTE DETERMINATION
Grant PGC1 proteins, meteorin-like and energy homeostasis
Academic Article Lysine-specific demethylase 1 promotes brown adipose tissue thermogenesis via repressing glucocorticoid activation.
Academic Article The Cancer Drug Dasatinib Increases PGC-1a in Adipose Tissue but Has Adverse Effects on Glucose Tolerance in Obese Mice.
Academic Article Mitochondrial Patch Clamp of Beige Adipocytes Reveals UCP1-Positive and UCP1-Negative Cells Both Exhibiting Futile Creatine Cycling.
Academic Article UCP1 deficiency causes brown fat respiratory chain depletion and sensitizes mitochondria to calcium overload-induced dysfunction.
Academic Article Genetic Depletion of Adipocyte Creatine Metabolism Inhibits Diet-Induced Thermogenesis and Drives Obesity.
Academic Article Mitochondrial reactive oxygen species and adipose tissue thermogenesis: Bridging physiology and mechanisms.
Academic Article CACHEXIA & BROWN FAT: A BURNING ISSUE IN CANCER.
Academic Article Crosstalk between KCNK3-Mediated Ion Current and Adrenergic Signaling Regulates Adipose Thermogenesis and Obesity.
Academic Article Brown Adipose Tissue Controls Skeletal Muscle Function via the Secretion of Myostatin.
Academic Article Irisin Mediates Effects on Bone and Fat via aV Integrin Receptors.
Academic Article New Advances in Adaptive Thermogenesis: UCP1 and Beyond.
Academic Article Innervation of thermogenic adipose tissue via a calsyntenin 3ß-S100b axis.
Academic Article ?d T cells and adipocyte IL-17RC control fat innervation and thermogenesis.
Academic Article Facultative protein selenation regulates redox sensitivity, adipose tissue thermogenesis, and obesity.
Search Criteria
  • Adipose Tissue
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.