Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Login and Edit functionaility are currrently unavailable.

Search Result Details

This page shows the details of why an item matched the keywords from your search.
One or more keywords matched the following items that are connected to D'Andrea, Alan
Item TypeName
Academic Article Spectrum of mutations in the Fanconi anaemia group G gene, FANCG/XRCC9.
Academic Article The interplay of Fanconi anemia proteins in the DNA damage response.
Academic Article The deubiquitinating enzyme USP1 regulates the Fanconi anemia pathway.
Academic Article A novel diagnostic screen for defects in the Fanconi anemia pathway.
Academic Article Regulation of the Fanconi anemia pathway by monoubiquitination.
Academic Article Natural gene therapy in monozygotic twins with Fanconi anemia.
Academic Article Function of the Fanconi anemia pathway in Fanconi anemia complementation group F and D1 cells.
Academic Article FANCD2 hurdles the DNA interstrand crosslink.
Academic Article Regulated binding of the Fanconi anemia proteins, FANCA and FANCC.
Academic Article Fanconi anemia and DNA repair.
Academic Article The Chinese hamster FANCG/XRCC9 mutant NM3 fails to express the monoubiquitinated form of the FANCD2 protein, is hypersensitive to a range of DNA damaging agents and exhibits a normal level of spontaneous sister chromatid exchange.
Academic Article Disruption of the Fanconi anemia-BRCA pathway in cisplatin-sensitive ovarian tumors.
Academic Article S-phase-specific interaction of the Fanconi anemia protein, FANCD2, with BRCA1 and RAD51.
Academic Article Carboxy terminal region of the Fanconi anemia protein, FANCG/XRCC9, is required for functional activity.
Academic Article Interaction of FANCD2 and NBS1 in the DNA damage response.
Academic Article Hematopoietic stem cell defects in mice with deficiency of Fancd2 or Usp1.
Academic Article Menin associates with FANCD2, a protein involved in repair of DNA damage.
Academic Article Regulated interaction of the Fanconi anemia protein, FANCD2, with chromatin.
Academic Article Nuclear localization of the Fanconi anemia protein FANCC is required for functional activity.
Academic Article The Fanconi Anemia/BRCA signaling pathway: disruption in cisplatin-sensitive ovarian cancers.
Academic Article Fanconi anemia proteins FANCA, FANCC, and FANCG/XRCC9 interact in a functional nuclear complex.
Academic Article The Fanconi anemia pathway is required for the DNA replication stress response and for the regulation of common fragile site stability.
Academic Article A UAF1-containing multisubunit protein complex regulates the Fanconi anemia pathway.
Academic Article Structural determinants of human FANCF protein that function in the assembly of a DNA damage signaling complex.
Academic Article XPF-ERCC1 participates in the Fanconi anemia pathway of cross-link repair.
Academic Article Bone marrow failure in Fanconi anemia is triggered by an exacerbated p53/p21 DNA damage response that impairs hematopoietic stem and progenitor cells.
Academic Article The WD40 repeats of FANCL are required for Fanconi anemia core complex assembly.
Academic Article Inhibition of the Nedd8 system sensitizes cells to DNA interstrand cross-linking agents.
Academic Article BRCA1 interacts directly with the Fanconi anemia protein FANCA.
Academic Article The Fanconi anaemia/BRCA pathway.
Academic Article A cytoplasmic serine protein kinase binds and may regulate the Fanconi anemia protein FANCA.
Academic Article The USP1/UAF1 complex promotes double-strand break repair through homologous recombination.
Academic Article Direct DNA binding activity of the Fanconi anemia D2 protein.
Academic Article Phosphorylation of FANCD2 on two novel sites is required for mitomycin C resistance.
Academic Article Bi-allelic silencing of the Fanconi anaemia gene FANCF in acute myeloid leukaemia.
Academic Article Functional interaction of monoubiquitinated FANCD2 and BRCA2/FANCD1 in chromatin.
Academic Article The Fanconi anemia (FA) pathway confers glioma resistance to DNA alkylating agents.
Academic Article Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair.
Academic Article Upregulation of Fanconi anemia DNA repair genes in melanoma compared with non-melanoma skin cancer.
Academic Article BRCA1 functions independently of homologous recombination in DNA interstrand crosslink repair.
Academic Article Human ELG1 regulates the level of ubiquitinated proliferating cell nuclear antigen (PCNA) through Its interactions with PCNA and USP1.
Academic Article Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway.
Academic Article The Fanconi road to cancer.
Academic Article A patient-derived mutant form of the Fanconi anemia protein, FANCA, is defective in nuclear accumulation.
Academic Article The Fanconi anemia protein, FANCE, promotes the nuclear accumulation of FANCC.
Academic Article Heterogeneous activation of the Fanconi anemia pathway by patient-derived FANCA mutants.
Academic Article Targeted disruption of the murine Fanconi anemia gene, Fancg/Xrcc9.
Academic Article Convergence of the fanconi anemia and ataxia telangiectasia signaling pathways.
Academic Article The fanconi anemia proteins FANCA and FANCG stabilize each other and promote the nuclear accumulation of the Fanconi anemia complex.
Academic Article Positional cloning of a novel Fanconi anemia gene, FANCD2.
Academic Article Inactivation of murine Usp1 results in genomic instability and a Fanconi anemia phenotype.
Academic Article Knockdown of zebrafish Fancd2 causes developmental abnormalities via p53-dependent apoptosis.
Academic Article Regulation of monoubiquitinated PCNA by DUB autocleavage.
Academic Article UBE2T is the E2 in the Fanconi anemia pathway and undergoes negative autoregulation.
Academic Article Functional analysis of patient-derived mutations in the Fanconi anemia gene, FANCG/XRCC9.
Academic Article ATR couples FANCD2 monoubiquitination to the DNA-damage response.
Academic Article Chk1-mediated phosphorylation of FANCE is required for the Fanconi anemia/BRCA pathway.
Academic Article Fanconi anemia pathway-deficient tumor cells are hypersensitive to inhibition of ataxia telangiectasia mutated.
Academic Article Knockdown of Fanconi anemia genes in human embryonic stem cells reveals early developmental defects in the hematopoietic lineage.
Academic Article Clinical variability of Fanconi anemia (type C) results from expression of an amino terminal truncated Fanconi anemia complementation group C polypeptide with partial activity.
Academic Article Overcoming reprogramming resistance of Fanconi anemia cells.
Academic Article DNA polymerase POLN participates in cross-link repair and homologous recombination.
Academic Article Detection of somatic mosaicism and classification of Fanconi anemia patients by analysis of the FA/BRCA pathway.
Academic Article UAF1 is a subunit of multiple deubiquitinating enzyme complexes.
Academic Article A new nuclease member of the FAN club.
Academic Article Human Fanconi anemia monoubiquitination pathway promotes homologous DNA repair.
Academic Article Non-specific chemical inhibition of the Fanconi anemia pathway sensitizes cancer cells to cisplatin.
Academic Article The Fanconi anemia polypeptide FACC is localized to the cytoplasm.
Concept Fanconi Anemia Complementation Group F Protein
Concept Fanconi Anemia Complementation Group L Protein
Concept Fanconi Anemia Complementation Group G Protein
Concept Fanconi Anemia Complementation Group D2 Protein
Concept Fanconi Anemia Complementation Group E Protein
Concept Fanconi Anemia Complementation Group A Protein
Concept Fanconi Anemia Complementation Group C Protein
Academic Article FANCD2 activates transcription of TAp63 and suppresses tumorigenesis.
Academic Article Proteasome inhibitors block DNA repair and radiosensitize non-small cell lung cancer.
Academic Article Stabilization of mutant BRCA1 protein confers PARP inhibitor and platinum resistance.
Academic Article HELQ promotes RAD51 paralogue-dependent repair to avert germ cell loss and tumorigenesis.
Academic Article Inactivation of Uaf1 causes defective homologous recombination and early embryonic lethality in mice.
Academic Article Small-molecule inhibitors of USP1 target ID1 degradation in leukemic cells.
Academic Article The carboxyl terminus of FANCE recruits FANCD2 to the Fanconi Anemia (FA) E3 ligase complex to promote the FA DNA repair pathway.
Academic Article Homologous-recombination-deficient tumours are dependent on Pol?-mediated repair.
Academic Article RNF4-mediated polyubiquitination regulates the Fanconi anemia/BRCA pathway.
Academic Article FANCD2 Maintains Fork Stability in BRCA1/2-Deficient Tumors and Promotes Alternative End-Joining DNA Repair.
Academic Article HSP90 Shapes the Consequences of Human Genetic Variation.
Academic Article A senataxin-associated exonuclease SAN1 is required for resistance to DNA interstrand cross-links.
Academic Article Functional analysis of Fanconi anemia mutations in China.
Academic Article Fanconi-BRCA pathway mutations in childhood T-cell acute lymphoblastic leukemia.
Academic Article Cooperation of the NEIL3 and Fanconi anemia/BRCA pathways in interstrand crosslink repair.
Academic Article FANCI functions as a repair/apoptosis switch in response to DNA crosslinks.
Search Criteria
  • Fanconi Anemia Complementation Group C Protein
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.