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One or more keywords matched the following items that are connected to D'Andrea, Alan
Item TypeName
Academic Article The interplay of Fanconi anemia proteins in the DNA damage response.
Academic Article Chemosensitization to cisplatin by inhibitors of the Fanconi anemia/BRCA pathway.
Academic Article S-phase-specific interaction of the Fanconi anemia protein, FANCD2, with BRCA1 and RAD51.
Academic Article The Fanconi Anemia/BRCA signaling pathway: disruption in cisplatin-sensitive ovarian cancers.
Academic Article BRCA1 interacts directly with the Fanconi anemia protein FANCA.
Academic Article The Fanconi anaemia/BRCA pathway.
Academic Article Compromised CDK1 activity sensitizes BRCA-proficient cancers to PARP inhibition.
Academic Article BRCA1 functions independently of homologous recombination in DNA interstrand crosslink repair.
Academic Article Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway.
Academic Article Chk1-mediated phosphorylation of FANCE is required for the Fanconi anemia/BRCA pathway.
Academic Article Cdk1 participates in BRCA1-dependent S phase checkpoint control in response to DNA damage.
Concept BRCA1 Protein
Academic Article Proteasome inhibitors block DNA repair and radiosensitize non-small cell lung cancer.
Academic Article Stabilization of mutant BRCA1 protein confers PARP inhibitor and platinum resistance.
Academic Article Synthetic lethality between CCNE1 amplification and loss of BRCA1.
Academic Article Crosstalk between the nucleotide excision repair and Fanconi anemia/BRCA pathways.
Academic Article RNF4-mediated polyubiquitination regulates the Fanconi anemia/BRCA pathway.
Academic Article A unique subset of epithelial ovarian cancers with platinum sensitivity and PARP inhibitor resistance.
Academic Article Association and prognostic significance of BRCA1/2-mutation status with neoantigen load, number of tumor-infiltrating lymphocytes and expression of PD-1/PD-L1 in high grade serous ovarian cancer.
Academic Article The BRCA1-?11q Alternative Splice Isoform Bypasses Germline Mutations and Promotes Therapeutic Resistance to PARP Inhibition and Cisplatin.
Academic Article FANCD2 Maintains Fork Stability in BRCA1/2-Deficient Tumors and Promotes Alternative End-Joining DNA Repair.
Academic Article CDK12 Inhibition Reverses De Novo and Acquired PARP Inhibitor Resistance in BRCA Wild-Type and Mutated Models of Triple-Negative Breast Cancer.
Academic Article EZH2 promotes degradation of stalled replication forks by recruiting MUS81 through histone H3 trimethylation.
Academic Article Mechanisms of PARP inhibitor sensitivity and resistance.
Academic Article CtIP-Mediated Fork Protection Synergizes with BRCA1 to Suppress Genomic Instability upon DNA Replication Stress.
Academic Article DYNLL1 binds to MRE11 to limit DNA end resection in BRCA1-deficient cells.
Academic Article USP1 Is Required for Replication Fork Protection in BRCA1-Deficient Tumors.
Academic Article Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets.
Academic Article TRIP13 regulates DNA repair pathway choice through REV7 conformational change.
Search Criteria
  • BRCA1 Protein
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.