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Comparison of front-loaded recombinant tissue-type plasminogen activator, anistreplase and combination thrombolytic therapy for acute myocardial infarction: results of the Thrombolysis in Myocardial Infarction (TIMI) 4 trial.
Clinical benefit of front-loaded tPA over combination thrombolytic therapy or APSAC for acute MI: results of the TIMI 4 trial