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Human mucin 1 oncoprotein represses transcription of the p53 tumor suppressor gene.
SPECIALIZED PROGRAM OF RESEARCH EXCELLENCE/BREAST CANCER
MUC1-C induces DNA methyltransferase 1 and represses tumor suppressor genes in acute myeloid leukemia.
MUC1-C activates polycomb repressive complexes and downregulates tumor suppressor genes in human cancer cells.