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One or more keywords matched the following items that are connected to Kufe, Donald
Item TypeName
Academic Article MUC1 cytoplasmic domain coactivates Wnt target gene transcription and confers transformation.
Academic Article DF3/MUC1 signaling in multiple myeloma cells is regulated by interleukin-7.
Academic Article Functional interaction between the c-Abl and Arg protein-tyrosine kinases in the oxidative stress response.
Academic Article The MUC1 and galectin-3 oncoproteins function in a microRNA-dependent regulatory loop.
Academic Article A broadly neutralizing monoclonal antibody that recognizes the V3 region of human immunodeficiency virus type 1 glycoprotein gp120.
Academic Article Human MUC1 oncoprotein regulates p53-responsive gene transcription in the genotoxic stress response.
Academic Article Functional targeting of the MUC1 oncogene in human cancers.
Academic Article Mucin 1 C-terminal subunit oncoprotein is a target for small-molecule inhibitors.
Academic Article Cell cycle phenotype-based optimization of G2-abrogating peptides yields CBP501 with a unique mechanism of action at the G2 checkpoint.
Academic Article Monocyte colony-stimulating factor stimulates binding of phosphatidylinositol 3-kinase to Grb2.Sos complexes in human monocytes.
Academic Article Activation of Raf-1 and mitogen-activated protein kinases during monocytic differentiation of human myeloid leukemia cells.
Academic Article c-Abl activation regulates induction of the SEK1/stress-activated protein kinase pathway in the cellular response to 1-beta-D-arabinofuranosylcytosine.
Academic Article Genomic structure, induction, and production of TNF-alpha.
Academic Article MUC1 oncoprotein is targeted to mitochondria by heregulin-induced activation of c-Src and the molecular chaperone HSP90.
Academic Article Negative regulation of cytochrome c-mediated oligomerization of Apaf-1 and activation of procaspase-9 by heat shock protein 90.
Academic Article Evolution of the human MUC1 oncoprotein.
Academic Article Cooperativity of the MUC1 oncoprotein and STAT1 pathway in poor prognosis human breast cancer.
Academic Article Proteolytic activation of protein kinase C delta by an ICE/CED 3-like protease induces characteristics of apoptosis.
Academic Article Frequent alteration of the DF3 tumor-associated antigen gene in primary human breast carcinomas.
Academic Article Targeting the human MUC1 oncoprotein: a tale of two proteins.
Academic Article Sequence analysis of the 5' region of the human DF3 breast carcinoma-associated antigen gene.
Academic Article A monoclonal antibody against the oncogenic mucin 1 cytoplasmic domain.
Academic Article Stimulation of human monocytes with macrophage colony-stimulating factor induces a Grb2-mediated association of the focal adhesion kinase pp125FAK and dynamin.
Academic Article Identification of a mutant human topoisomerase I with intact catalytic activity and resistance to 9-nitro-camptothecin.
Academic Article Interaction of glycogen synthase kinase 3beta with the DF3/MUC1 carcinoma-associated antigen and beta-catenin.
Academic Article Protein kinase C delta regulates function of the DF3/MUC1 carcinoma antigen in beta-catenin signaling.
Academic Article The stress response to ionizing radiation involoves c-Abl-dependent phosphorylation of SHPTP1.
Academic Article Inhibition of the MUC1-C oncoprotein is synergistic with cytotoxic agents in the treatment of breast cancer cells.
Academic Article Membrane-derived second messenger regulates x-ray-mediated tumor necrosis factor alpha gene induction.
Academic Article Interaction of human MUC1 and beta-catenin is regulated by Lck and ZAP-70 in activated Jurkat T cells.
Academic Article Survival of human multiple myeloma cells is dependent on MUC1 C-terminal transmembrane subunit oncoprotein function.
Academic Article MUC1 oncoprotein functions in activation of fibroblast growth factor receptor signaling.
Academic Article The role of intracellular calcium in the cellular response to ionizing radiation.
Academic Article Activation of serine/threonine protein kinases and early growth response 1 gene expression by tumor necrosis factor in human myeloid leukemia cells.
Academic Article MUC1 oncoprotein is a druggable target in human prostate cancer cells.
Academic Article Activation of protein kinase Cdelta in human myeloid leukemia cells treated with 1-beta-D-arabinofuranosylcytosine.
Academic Article Direct targeting of the mucin 1 oncoprotein blocks survival and tumorigenicity of human breast carcinoma cells.
Academic Article Dependence on the MUC1-C oncoprotein in non-small cell lung cancer cells.
Academic Article Identification of a nucleolin binding site in human topoisomerase I.
Academic Article Activation of the c-Abl tyrosine kinase in the stress response to DNA-damaging agents.
Academic Article Activation of Src-like p56/p53lyn tyrosine kinase by ionizing radiation.
Academic Article Association of the DF3/MUC1 breast cancer antigen with Grb2 and the Sos/Ras exchange protein.
Academic Article p56/p53lyn tyrosine kinase activation in mammalian cells treated with mitomycin C.
Academic Article MUC1-C oncoprotein suppresses reactive oxygen species-induced terminal differentiation of acute myelogenous leukemia cells.
Academic Article 1-beta-D-arabinofuranosylcytosine activates tyrosine phosphorylation of p34cdc2 and its association with the Src-like p56/p53lyn kinase in human myeloid leukemia cells.
Academic Article 1-beta-D-arabinofuranosylcytosine activates tyrosine phosphorylation of p34cdc2 and its association with the Src-like p56/p53lyn kinase in human myeloid leukemia cells.
Academic Article MUC1-C oncoprotein regulates glycolysis and pyruvate kinase M2 activity in cancer cells.
Concept Amino Acid Sequence
Academic Article Targeting the MUC1-C oncoprotein inhibits self-renewal capacity of breast cancer cells.
Academic Article Intracellular Targeting of the Oncogenic MUC1-C Protein with a Novel GO-203 Nanoparticle Formulation.
Academic Article Characterization of the MUC1-C Cytoplasmic Domain as a Cancer Target.
Academic Article Functional interactions of the cystine/glutamate antiporter, CD44v and MUC1-C oncoprotein in triple-negative breast cancer cells.
Academic Article MUC1-C activates BMI1 in human cancer cells.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.