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One or more keywords matched the following items that are connected to Chen, Xinhua
Item TypeName
Academic Article Association between IgG2 and IgG3 subclass responses to toxin A and recurrent Clostridium difficile-associated disease.
Academic Article Saccharomyces boulardii inhibits ERK1/2 mitogen-activated protein kinase activation both in vitro and in vivo and protects against Clostridium difficile toxin A-induced enteritis.
Academic Article Toll-like receptor 5-dependent immunogenicity and protective efficacy of a recombinant fusion protein vaccine containing the nontoxic domains of Clostridium difficile toxins A and B and Salmonella enterica serovar typhimurium flagellin in a mouse model of Clostridium difficile disease.
Concept Bacterial Toxins
Academic Article Human monoclonal antibodies against Clostridium difficile toxins A and B inhibit inflammatory and histologic responses to the toxins in human colon and peripheral blood monocytes.
Academic Article Mortality in patients with Clostridium difficile infection correlates with host pro-inflammatory and humoral immune responses.
Academic Article In vitro and in vivo antibacterial evaluation of cadazolid, a new antibiotic for treatment of Clostridium difficile infections.
Academic Article A novel multivalent, single-domain antibody targeting TcdA and TcdB prevents fulminant Clostridium difficile infection in mice.
Academic Article Fidaxomicin inhibits Clostridium difficile toxin A-mediated enteritis in the mouse ileum.
Academic Article Toxin-mediated paracellular transport of antitoxin antibodies facilitates protection against Clostridium difficile infection.
Academic Article Differential immunodetection of toxin B from highly virulent Clostridium difficile BI/NAP-1/027.
Academic Article Development and Validation of Digital Enzyme-Linked Immunosorbent Assays for Ultrasensitive Detection and Quantification of Clostridium difficile Toxins in Stool.
Academic Article Host Immune Response to Clostridium difficile Infection in Inflammatory Bowel Disease Patients.
Academic Article Fidaxomicin and OP-1118 Inhibit Clostridium difficile Toxin A- and B-Mediated Inflammatory Responses via Inhibition of NF-?B Activity.
Academic Article Comparison of Clostridioides difficile Stool Toxin Concentrations in Adults With Symptomatic Infection and Asymptomatic Carriage Using an Ultrasensitive Quantitative Immunoassay.
Academic Article Clostridium difficile toxins induce VEGF-A and vascular permeability to promote disease pathogenesis.
Academic Article Host Immune Markers Distinguish Clostridioides difficile Infection From Asymptomatic Carriage and Non-C. difficile Diarrhea.
Academic Article Toxin A-Predominant Pathogenic Clostridioides difficile: A Novel Clinical Phenotype.
Academic Article Therapeutic Mechanism of Macrophage Inflammatory Protein 1 a Neutralizing Antibody (CCL3) in Clostridium difficile Infection in Mice.
Academic Article Clostridioides difficile Toxin A Remodels Membranes and Mediates DNA Entry Into Cells to Activate Toll-Like Receptor 9 Signaling.
Academic Article Absence of Toxemia in Clostridioides difficile Infection: Results from Ultrasensitive Toxin Assay of Serum.
Search Criteria
  • Bacterial Toxins
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.