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One or more keywords matched the following items that are connected to Chiocca, E.
Item TypeName
Academic Article Herpes vector-mediated delivery of marker genes to disseminated central nervous system tumors.
Academic Article Comparative analyses of transgene delivery and expression in tumors inoculated with a replication-conditional or -defective viral vector.
Academic Article Improved HSV-1 amplicon packaging system using ICP27-deleted, oversized HSV-1 BAC DNA.
Academic Article An oncolytic viral mutant that delivers the CYP2B1 transgene and augments cyclophosphamide chemotherapy.
Academic Article Positron emission tomography-based imaging of transgene expression mediated by replication-conditional, oncolytic herpes simplex virus type 1 mutant vectors in vivo.
Academic Article [Herpes simplex type-1 virus-based vectors for gene therapy].
Academic Article Altered expression of antiviral cytokine mRNAs associated with cyclophosphamide's enhancement of viral oncolysis.
Academic Article Brain tumor oncolysis with replication-conditional herpes simplex virus type 1 expressing the prodrug-activating genes, CYP2B1 and secreted human intestinal carboxylesterase, in combination with cyclophosphamide and irinotecan.
Academic Article Cyclophosphamide enhances glioma virotherapy by inhibiting innate immune responses.
Academic Article Transfer and expression of the lacZ gene in rat brain neurons mediated by herpes simplex virus mutants.
Academic Article Cyclophosphamide allows for in vivo dose reduction of a potent oncolytic virus.
Academic Article Development of a rapid method to generate multiple oncolytic HSV vectors and their in vivo evaluation using syngeneic mouse tumor models.
Academic Article Histone deacetylase inhibitors augment antitumor efficacy of herpes-based oncolytic viruses.
Academic Article Antitumor efficacy of 34.5ENVE: a transcriptionally retargeted and "Vstat120"-expressing oncolytic virus.
Academic Article Cytotoxicity, apoptosis, and viral replication in tumor cells treated with oncolytic ribonucleotide reductase-defective herpes simplex type 1 virus (hrR3) combined with ionizing radiation.
Academic Article Oncolytic viruses.
Academic Article Glioma virotherapy: effects of innate immune suppression and increased viral replication capacity.
Academic Article Replicative oncolytic herpes simplex viruses in combination cancer therapies.
Academic Article A phase I open-label, dose-escalation, multi-institutional trial of injection with an E1B-Attenuated adenovirus, ONYX-015, into the peritumoral region of recurrent malignant gliomas, in the adjuvant setting.
Academic Article Complement depletion facilitates the infection of multiple brain tumors by an intravascular, replication-conditional herpes simplex virus mutant.
Academic Article Phase ib trial of oncolytic herpes virus G207 shows safety of multiple injections and documents viral replication.
Academic Article Oncolytic viruses driven by tumor-specific promoters.
Academic Article Enhancement of interleukin-4-mediated tumor regression in athymic mice by in situ retroviral gene transfer.
Academic Article Multimodal cancer treatment mediated by a replicating oncolytic virus that delivers the oxazaphosphorine/rat cytochrome P450 2B1 and ganciclovir/herpes simplex virus thymidine kinase gene therapies.
Academic Article An HSV amplicon-based helper system for helper-dependent adenoviral vectors.
Academic Article Effects of innate immunity on herpes simplex virus and its ability to kill tumor cells.
Academic Article An oncolytic herpes simplex virus type 1 selectively destroys diffuse liver metastases from colon carcinoma.
Academic Article Regulation of herpes simplex virus gamma(1)34.5 expression and oncolysis of diffuse liver metastases by Myb34.5.
Academic Article Therapeutic efficiency and safety of a second-generation replication-conditional HSV1 vector for brain tumor gene therapy.
Academic Article Tissue inhibitor of metalloproteinase-3 expression from an oncolytic adenovirus inhibits matrix metalloproteinase activity in vivo without affecting antitumor efficacy in malignant glioma.
Academic Article Directing systemic oncolytic viral delivery to tumors via carrier cells.
Academic Article Imaging immediate-early and strict-late promoter activity during oncolytic herpes simplex virus type 1 infection and replication in tumors.
Academic Article Effective treatment of an orthotopic xenograft model of human glioblastoma using an EGFR-retargeted oncolytic herpes simplex virus.
Academic Article Oncolytic herpes virus with defective ICP6 specifically replicates in quiescent cells with homozygous genetic mutations in p16.
Academic Article Prodrug bioactivation and oncolysis of diffuse liver metastases by a herpes simplex virus 1 mutant that expresses the CYP2B1 transgene.
Academic Article Copper chelation enhances antitumor efficacy and systemic delivery of oncolytic HSV.
Concept Virus Replication
Academic Article Cytomegalovirus contributes to glioblastoma in the context of tumor suppressor mutations.
Academic Article STAT3 activation promotes oncolytic HSV1 replication in glioma cells.
Academic Article DNA demethylating agents synergize with oncolytic HSV1 against malignant gliomas.
Academic Article Switching a replication-defective adenoviral vector into a replication-competent, oncolytic adenovirus.
Academic Article Oncolytic viruses targeting tumor stem cells.
Academic Article Histone deacetylase 6 inhibition enhances oncolytic viral replication in glioma.
Academic Article In vitro screening of clinical drugs identifies sensitizers of oncolytic viral therapy in glioblastoma stem-like cells.
Academic Article Use of miRNA response sequences to block off-target replication and increase the safety of an unattenuated, glioblastoma-targeted oncolytic HSV.
Academic Article Toxicity and Efficacy of a Novel GADD34-expressing Oncolytic HSV-1 for the Treatment of Experimental Glioblastoma.
Academic Article Arming an Oncolytic Herpes Simplex Virus Type 1 with a Single-chain Fragment Variable Antibody against PD-1 for Experimental Glioblastoma Therapy.
Search Criteria
  • Virus Replication
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.