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One or more keywords matched the following items that are connected to Chiocca, E.
Item TypeName
Academic Article Enhancement of gene therapy specificity for diffuse colon carcinoma liver metastases with recombinant herpes simplex virus.
Academic Article Herpes vector-mediated delivery of marker genes to disseminated central nervous system tumors.
Academic Article Comparative analyses of transgene delivery and expression in tumors inoculated with a replication-conditional or -defective viral vector.
Academic Article Improved HSV-1 amplicon packaging system using ICP27-deleted, oversized HSV-1 BAC DNA.
Academic Article Genetically engineered herpes simplex viral vectors in the treatment of brain tumors: a review.
Academic Article Contribution of bone marrow-derived cells to blood vessels in ischemic tissues and tumors.
Academic Article Potentiated gene delivery to tumors using herpes simplex virus/Epstein-Barr virus/RV tribrid amplicon vectors.
Academic Article The effect of ganciclovir on herpes simplex virus-mediated oncolysis.
Academic Article Herpes simplex virus type 1 DNA amplified as bacterial artificial chromosome in Escherichia coli: rescue of replication-competent virus progeny and packaging of amplicon vectors.
Academic Article Improved helper virus-free packaging system for HSV amplicon vectors using an ICP27-deleted, oversized HSV-1 DNA in a bacterial artificial chromosome.
Academic Article Positron emission tomography-based imaging of transgene expression mediated by replication-conditional, oncolytic herpes simplex virus type 1 mutant vectors in vivo.
Academic Article A novel 'piggyback' packaging system for herpes simplex virus amplicon vectors.
Academic Article Influence of p53 on herpes simplex virus type 1 vectors for cancer gene therapy.
Academic Article The combination of adenoviral HSV TK gene therapy and radiation is effective in athymic mouse glioblastoma xenografts without increasing toxic side effects.
Academic Article Altered expression of antiviral cytokine mRNAs associated with cyclophosphamide's enhancement of viral oncolysis.
Academic Article Brain tumor oncolysis with replication-conditional herpes simplex virus type 1 expressing the prodrug-activating genes, CYP2B1 and secreted human intestinal carboxylesterase, in combination with cyclophosphamide and irinotecan.
Academic Article Cyclophosphamide enhances glioma virotherapy by inhibiting innate immune responses.
Academic Article Transfer and expression of the lacZ gene in rat brain neurons mediated by herpes simplex virus mutants.
Academic Article B-myb promoter retargeting of herpes simplex virus gamma34.5 gene-mediated virulence toward tumor and cycling cells.
Academic Article Development of a rapid method to generate multiple oncolytic HSV vectors and their in vivo evaluation using syngeneic mouse tumor models.
Academic Article Marker gene transfer and oncolysis of human Y79 retinoblastoma cells mediated by herpes simplex virus mutants.
Academic Article Cancer gene therapy using a replication-competent herpes simplex virus type 1 vector.
Academic Article Inhibition of NF2-negative and NF2-positive primary human meningioma cell proliferation by overexpression of merlin due to vector-mediated gene transfer.
Academic Article Replicative oncolytic herpes simplex viruses in combination cancer therapies.
Academic Article Complement depletion facilitates the infection of multiple brain tumors by an intravascular, replication-conditional herpes simplex virus mutant.
Academic Article The histone deacetylase inhibitor valproic acid lessens NK cell action against oncolytic virus-infected glioblastoma cells by inhibition of STAT5/T-BET signaling and generation of gamma interferon.
Academic Article Early STAT1 activation after systemic delivery of HSV amplicon vectors suppresses transcription of the vector-encoded transgene.
Academic Article Phase ib trial of oncolytic herpes virus G207 shows safety of multiple injections and documents viral replication.
Academic Article Pre-existing herpes simplex virus 1 (HSV-1) immunity decreases, but does not abolish, gene transfer to experimental brain tumors by a HSV-1 vector.
Academic Article Multimodal cancer treatment mediated by a replicating oncolytic virus that delivers the oxazaphosphorine/rat cytochrome P450 2B1 and ganciclovir/herpes simplex virus thymidine kinase gene therapies.
Academic Article Single-step conversion of cells to retrovirus vector producers with herpes simplex virus-Epstein-Barr virus hybrid amplicons.
Academic Article Oncolytic viruses as novel anticancer agents: turning one scourge against another.
Academic Article Effects of innate immunity on herpes simplex virus and its ability to kill tumor cells.
Academic Article Long-term survival in a rodent brain tumor model by bradykinin-enhanced intra-arterial delivery of a therapeutic herpes simplex virus vector.
Academic Article An oncolytic herpes simplex virus type 1 selectively destroys diffuse liver metastases from colon carcinoma.
Academic Article Regulation of herpes simplex virus gamma(1)34.5 expression and oncolysis of diffuse liver metastases by Myb34.5.
Academic Article Comparison of intracerebral inoculation and osmotic blood-brain barrier disruption for delivery of adenovirus, herpesvirus, and iron oxide particles to normal rat brain.
Academic Article Efficacy and safety of the oncolytic herpes simplex virus rRp450 alone and combined with cyclophosphamide.
Academic Article Stable transgene expression from HSV amplicon vectors in the brain: potential involvement of immunoregulatory signals.
Academic Article Imaging immediate-early and strict-late promoter activity during oncolytic herpes simplex virus type 1 infection and replication in tumors.
Academic Article Effective treatment of an orthotopic xenograft model of human glioblastoma using an EGFR-retargeted oncolytic herpes simplex virus.
Academic Article Antitumor activity and reporter gene transfer into rat brain neoplasms inoculated with herpes simplex virus vectors defective in thymidine kinase or ribonucleotide reductase.
Academic Article Oncolytic herpes virus with defective ICP6 specifically replicates in quiescent cells with homozygous genetic mutations in p16.
Academic Article Enhanced antitumor efficacy of vasculostatin (Vstat120) expressing oncolytic HSV-1.
Academic Article Design and application of oncolytic HSV vectors for glioblastoma therapy.
Academic Article Prodrug bioactivation and oncolysis of diffuse liver metastases by a herpes simplex virus 1 mutant that expresses the CYP2B1 transgene.
Academic Article Gene transfer into experimental brain tumors mediated by adenovirus, herpes simplex virus, and retrovirus vectors.
Academic Article Copper chelation enhances antitumor efficacy and systemic delivery of oncolytic HSV.
Academic Article NK cells impede glioblastoma virotherapy through NKp30 and NKp46 natural cytotoxicity receptors.
Academic Article Long-term survival of rats harboring brain neoplasms treated with ganciclovir and a herpes simplex virus vector that retains an intact thymidine kinase gene.
Academic Article Nerve growth factor protects against herpes simplex virus type 1 neurotoxicity in the rat striatum.
Academic Article ICP0 inhibits the decrease of HSV amplicon-mediated transgene expression.
Concept Simplexvirus
Academic Article Comparative effectiveness of antinociceptive gene therapies in animal models of diabetic neuropathic pain.
Academic Article TGFß Treatment Enhances Glioblastoma Virotherapy by Inhibiting the Innate Immune Response.
Academic Article Phase II multicenter study of gene-mediated cytotoxic immunotherapy as adjuvant to surgical resection for newly diagnosed malignant glioma.
Academic Article A combinational therapy of EGFR-CAR NK cells and oncolytic herpes simplex virus 1 for breast cancer brain metastases.
Academic Article The Fc Domain of Immunoglobulin Is Sufficient to Bridge NK Cells with Virally Infected Cells.
Academic Article Arming an Oncolytic Herpes Simplex Virus Type 1 with a Single-chain Fragment Variable Antibody against PD-1 for Experimental Glioblastoma Therapy.
Academic Article Correction: Arming an Oncolytic Herpes Simplex Virus Type 1 with a Single-chain Fragment Variable Antibody against PD-1 for Experimental Glioblastoma Therapy.
Academic Article Oncolytic HSV Vectors and Anti-Tumor Immunity.
Academic Article The Current Landscape of Oncolytic Herpes Simplex Viruses as Novel Therapies for Brain Malignancies.
Search Criteria
  • Simplexvirus
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.