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One or more keywords matched the following items that are connected to Zon, Leonard
Item TypeName
Academic Article Use of the zebrafish (Danio rerio) to define hematopoiesis.
Academic Article The zebrafish: a new model of T-cell and thymic development.
Academic Article Zebrafish: a model system for the study of human disease.
Academic Article Protein-damaging stresses activate c-Jun N-terminal kinase via inhibition of its dephosphorylation: a novel pathway controlled by HSP72.
Academic Article Duplicate VegfA genes and orthologues of the KDR receptor tyrosine kinase family mediate vascular development in the zebrafish.
Academic Article Construction and application of a zebrafish array comparative genomic hybridization platform.
Academic Article Oncogenic NRAS cooperates with p53 loss to generate melanoma in zebrafish.
Academic Article In vivo drug discovery in the zebrafish.
Academic Article Myc-induced T cell leukemia in transgenic zebrafish.
Academic Article BRAF mutations are sufficient to promote nevi formation and cooperate with p53 in the genesis of melanoma.
Academic Article Zebrafish: a new model for human disease.
Academic Article Dissecting hematopoiesis and disease using the zebrafish.
Academic Article Hematopoietic development in the zebrafish.
Academic Article Stem cell migration: a zebrafish model.
Academic Article Zebrafish: a genetic approach in studying hematopoiesis.
Academic Article Realizing the potential of zebrafish as a model for human disease.
Academic Article Self-renewal versus differentiation, a job for the mighty morphogens.
Academic Article The 'definitive' (and 'primitive') guide to zebrafish hematopoiesis.
Academic Article Notch and MAML signaling drives Scl-dependent interneuron diversity in the spinal cord.
Academic Article Positional cloning of the zebrafish sauternes gene: a model for congenital sideroblastic anaemia.
Academic Article montalcino, A zebrafish model for variegate porphyria.
Academic Article Ultrasound biomicroscopy permits in vivo characterization of zebrafish liver tumors.
Academic Article Cdx4 dysregulates Hox gene expression and generates acute myeloid leukemia alone and in cooperation with Meis1a in a murine model.
Academic Article Characterization of zebrafish full-length prothrombin cDNA and linkage group mapping.
Academic Article Zebrafish orthologs of human muscular dystrophy genes.
Academic Article Zebrafish tumor assays: the state of transplantation.
Academic Article The dystrophin associated protein complex in zebrafish.
Academic Article The clinical potential of stem cells.
Academic Article New waves of discovery: modeling cancer in zebrafish.
Academic Article Mlck1a is expressed in zebrafish thrombocytes and is an essential component of thrombus formation.
Academic Article Zebrafish stat3 is expressed in restricted tissues during embryogenesis and stat1 rescues cytokine signaling in a STAT1-deficient human cell line.
Academic Article The use of zebrafish to understand immunity.
Academic Article Definition of the zebrafish genome using flow cytometry and cytogenetic mapping.
Academic Article High-throughput cell transplantation establishes that tumor-initiating cells are abundant in zebrafish T-cell acute lymphoblastic leukemia.
Academic Article Transparent adult zebrafish as a tool for in vivo transplantation analysis.
Academic Article Modeling Diamond Blackfan anemia in the zebrafish.
Academic Article Zebrafish as a model for normal and malignant hematopoiesis.
Academic Article Hematopoietic stem cells, hematopoiesis and disease: lessons from the zebrafish model.
Academic Article Modeling human hematopoietic and cardiovascular diseases in zebrafish.
Academic Article Zebrafish as a cancer model system.
Academic Article Teleost growth factor independence (gfi) genes differentially regulate successive waves of hematopoiesis.
Academic Article A model for primary melanoma of the CNS implicates NRAS.
Academic Article Characterization of immune-matched hematopoietic transplantation in zebrafish.
Academic Article The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset.
Academic Article The zebrafish. Preface.
Academic Article Hooked! Modeling human disease in zebrafish.
Academic Article Phospholipase C gamma-1 is required for granulocyte maturation in zebrafish.
Academic Article Fishing at the cellular level.
Academic Article Myelopoiesis in the zebrafish, Danio rerio.
Academic Article Evolutionary conservation of zebrafish linkage group 14 with frequently deleted regions of human chromosome 5 in myeloid malignancies.
Academic Article Transcriptional regulation of blood formation during Xenopus development.
Academic Article Hematopoietic defects in rps29 mutant zebrafish depend upon p53 activation.
Academic Article Characterization of zebrafish merlot/chablis as non-mammalian vertebrate models for severe congenital anemia due to protein 4.1 deficiency.
Academic Article Prostaglandin E2 enhances human cord blood stem cell xenotransplants and shows long-term safety in preclinical nonhuman primate transplant models.
Academic Article Stromal cell-derived factor-1 and hematopoietic cell homing in an adult zebrafish model of hematopoietic cell transplantation.
Academic Article The zebrafish as a model organism to study development of the immune system.
Academic Article The zebrafish dag1 mutant: a novel genetic model for dystroglycanopathies.
Academic Article Taking human cancer genes to the fish: a transgenic model of melanoma in zebrafish.
Academic Article Zebrafish models of p53 functions.
Academic Article The chianti zebrafish mutant provides a model for erythroid-specific disruption of transferrin receptor 1.
Academic Article Use of zebrafish models for the analysis of human disease.
Academic Article The ERGonomics of hematopoietic stem cell self-renewal.
Academic Article DHODH modulates transcriptional elongation in the neural crest and melanoma.
Academic Article Use of the zebrafish system to study primitive and definitive hematopoiesis.
Academic Article Regulation of stem cells in the zebra fish hematopoietic system.
Concept Models, Molecular
Concept Models, Animal
Concept Models, Genetic
Concept Models, Immunological
Concept Disease Models, Animal
Concept Models, Biological
Concept Models, Organizational
Concept Xenograft Model Antitumor Assays
Academic Article A healthy community through health system partnerships: the approach of Markham Stouffville Hospital.
Academic Article Zebrafish rhabdomyosarcoma reflects the developmental stage of oncogene expression during myogenesis.
Academic Article Zebrafish cancer: the state of the art and the path forward.
Academic Article Of fish and men: using zebrafish to fight human diseases.
Academic Article The genetic heterogeneity and mutational burden of engineered melanomas in zebrafish models.
Academic Article A zebrafish model of myelodysplastic syndrome produced through tet2 genomic editing.
Academic Article A CRISPR/Cas9 vector system for tissue-specific gene disruption in zebrafish.
Academic Article From fish tank to bedside in cancer therapy: an interview with Leonard Zon.
Academic Article A Quantitative System for Studying Metastasis Using Transparent Zebrafish.
Academic Article A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation.
Academic Article Identifying Novel Cancer Therapies Using Chemical Genetics and Zebrafish.
Academic Article Engineering Hematopoietic Stem Cells: Lessons from Development.
Academic Article Modeling human diseases: an education in interactions and interdisciplinary approaches.
Academic Article Long-term drug administration in the adult zebrafish using oral gavage for cancer preclinical studies.
Grant ERYTHROPOIETIN LIGAND-RECEPTOR INTERACTION
Grant A CENTER OF MOLECULAR DEVELOPMENTAL HEMATOPOIESIS
Grant Mount Desert Island Stem Cell Symposium
Grant International Society for Stem Cell Research Meeting
Grant Mount Desert Island Stem Cell Symposium
Grant Customized stem cells for clinical application in blood disorders
Grant Characterizing the Zebrafish Genome
Grant Cancer Biology in the Zebrafish
Grant A Community Zebrafish Resource for Modeling GWAS Biology
Grant A CENTER OF MOLECULAR HEMATOLOGY
Grant Fetal Globin Silencing
Grant A Comparative Approach To Globin Regulation/Thalassemia
Grant Induced Pluripotent Cells for Blood Diseases
Grant Human Pluripotent Stem Cell and Progenitor Models of Cardiac and Blood Diseases
Grant CHARACTERIZING THE ZEBRAFISH GENOME
Academic Article CAT7 and cat7l Long Non-coding RNAs Tune Polycomb Repressive Complex 1 Function during Human and Zebrafish Development.
Grant Stem cells for therapeutics discovery in genetic blood disorders
Academic Article c-myb hyperactivity leads to myeloid and lymphoid malignancies in zebrafish.
Academic Article From fish bowl to bedside: The power of zebrafish to unravel melanoma pathogenesis and discover new therapeutics.
Academic Article Neural crest state activation in NRAS driven melanoma, but not in NRAS-driven melanocyte expansion.
Academic Article JDP2: An oncogenic bZIP transcription factor in T cell acute lymphoblastic leukemia.
Academic Article Zebrafish blastomere screen identifies retinoic acid suppression of MYB in adenoid cystic carcinoma.
Academic Article Generation of mouse-zebrafish hematopoietic tissue chimeric embryos for hematopoiesis and host-pathogen interaction studies.
Academic Article Human tumor genomics and zebrafish modeling identify SPRED1 loss as a driver of mucosal melanoma.
Academic Article Modeling Cancer with Flies and Fish.
Academic Article Zebrafish modeling reveals that SPINT1 regulates the aggressiveness of skin cutaneous melanoma and its crosstalk with tumor immune microenvironment.
Academic Article Use of Zebrafish in Drug Discovery Toxicology.
Academic Article From blood development to disease: a paradigm for clinical translation.
Academic Article Zebrafish patient avatars in cancer biology and precision cancer therapy.
Academic Article Massively parallel reporter assays of melanoma risk variants identify MX2 as a gene promoting melanoma.
Grant Molecular Circuits in the Hematopoietic Stem Cell Niche
Academic Article Blood in the water: recent uses of zebrafish to study myeloid biology.
Academic Article Melanoma models for the next generation of therapies.
Academic Article Identification of Basp1 as a novel angiogenesis-regulating gene by multi-model system studies.
Academic Article Zebrafish disease models in drug discovery: from preclinical modelling to clinical trials.
Academic Article Mitochondrial function in development and disease.
Search Criteria
  • Modelling
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.