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One or more keywords matched the following items that are connected to Pandolfi, Pier Paolo
Item TypeName
Academic Article Targeting aberrant transcriptional repression in acute myeloid leukemia.
Academic Article Dok-1 independently attenuates Ras/mitogen-activated protein kinase and Src/c-myc pathways to inhibit platelet-derived growth factor-induced mitogenesis.
Academic Article Pten dose dictates cancer progression in the prostate.
Academic Article The t(8;21) fusion protein, AML1 ETO, specifically represses the transcription of the p14(ARF) tumor suppressor in acute myeloid leukemia.
Academic Article Role of Dok-1 and Dok-2 in leukemia suppression.
Academic Article Sox2 deficiency causes neurodegeneration and impaired neurogenesis in the adult mouse brain.
Academic Article RARalpha-PLZF overcomes PLZF-mediated repression of CRABPI, contributing to retinoid resistance in t(11;17) acute promyelocytic leukemia.
Academic Article Promyelocytic leukemia protein mediates interferon-based anti-herpes simplex virus 1 effects.
Academic Article Pml represses tumour progression through inhibition of mTOR.
Academic Article Differential requirement of mTOR in postmitotic tissues and tumorigenesis.
Academic Article Initiation of mRNA translation in oncogenesis: the role of eIF4E.
Academic Article Dok1 and SHIP act as negative regulators of v-Abl-induced pre-B cell transformation, proliferation and Ras/Erk activation.
Academic Article PML targeting eradicates quiescent leukaemia-initiating cells.
Academic Article Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer.
Academic Article eIF4E phosphorylation promotes tumorigenesis and is associated with prostate cancer progression.
Academic Article Differential expression of S6K2 dictates tissue-specific requirement for S6K1 in mediating aberrant mTORC1 signaling and tumorigenesis.
Academic Article The ETS protein MEF plays a critical role in perforin gene expression and the development of natural killer and NK-T cells.
Academic Article Physical and functional link of the leukemia-associated factors AML1 and PML.
Academic Article Role of the proto-oncogene Pokemon in cellular transformation and ARF repression.
Academic Article The TLX1 oncogene drives aneuploidy in T cell transformation.
Academic Article Functional antagonism between Sall4 and Plzf defines germline progenitors.
Academic Article Molecular genetics of acute lymphoblastic leukemia.
Academic Article A coding-independent function of gene and pseudogene mRNAs regulates tumour biology.
Academic Article CIP2A promotes proliferation of spermatogonial progenitor cells and spermatogenesis in mice.
Academic Article A novel type of cellular senescence that can be enhanced in mouse models and human tumor xenografts to suppress prostate tumorigenesis.
Academic Article Targeting of the tumor suppressor GRHL3 by a miR-21-dependent proto-oncogenic network results in PTEN loss and tumorigenesis.
Academic Article Plzf mediates transcriptional repression of HoxD gene expression through chromatin remodeling.
Academic Article Loss of the tumor suppressor PML in human cancers of multiple histologic origins.
Academic Article Downstream of tyrosine kinases-1 and Src homology 2-containing inositol 5'-phosphatase are required for regulation of CD4+CD25+ T cell development.
Academic Article The cytoplasmic NPM mutant induces myeloproliferation in a transgenic mouse model.
Academic Article LRF is an essential downstream target of GATA1 in erythroid development and regulates BIM-dependent apoptosis.
Academic Article PML is a direct p53 target that modulates p53 effector functions.
Academic Article TSPYL5 suppresses p53 levels and function by physical interaction with USP7.
Academic Article PTEN and TNF-alpha regulation of the intestinal-specific Cdx-2 homeobox gene through a PI3K, PKB/Akt, and NF-kappaB-dependent pathway.
Academic Article Amplification of the angiogenic signal through the activation of the TSC/mTOR/HIF axis by the KSHV vGPCR in Kaposi's sarcoma.
Academic Article A ceRNA hypothesis: the Rosetta Stone of a hidden RNA language?
Academic Article Coding-independent regulation of the tumor suppressor PTEN by competing endogenous mRNAs.
Academic Article Promyelocytic leukemia zinc finger protein activates GATA4 transcription and mediates cardiac hypertrophic signaling from angiotensin II receptor 2.
Academic Article Up-regulation of translation eukaryotic initiation factor 4E in nucleophosmin 1 haploinsufficient cells results in changes in CCAAT enhancer-binding protein a activity: implications in myelodysplastic syndrome and acute myeloid leukemia.
Academic Article Promyelocytic leukemia protein 4 induces apoptosis by inhibition of survivin expression.
Academic Article Subtle variations in Pten dose determine cancer susceptibility.
Academic Article PML, YAP, and p73 are components of a proapoptotic autoregulatory feedback loop.
Academic Article SnapShot: PTEN signaling pathways.
Academic Article Promyelocytic leukemia zinc finger protein regulates interferon-mediated innate immunity.
Academic Article Eradication of acute promyelocytic leukemia-initiating cells through PML-RARA degradation.
Academic Article The functions and regulation of the PTEN tumour suppressor.
Academic Article PML interacts with Myc, and Myc target gene expression is altered in PML-null fibroblasts.
Academic Article Repression of kit expression by Plzf in germ cells.
Academic Article Identification of DOK genes as lung tumor suppressors.
Academic Article Functional connection between Rad51 and PML in homology-directed repair.
Concept Gene Expression Regulation, Viral
Concept Gene Expression Regulation, Neoplastic
Concept Gene Expression Regulation, Enzymologic
Concept Gene Expression Regulation, Developmental
Concept Gene Expression Regulation
Concept Gene Expression Regulation, Leukemic
Academic Article The oncogenic microRNA miR-22 targets the TET2 tumor suppressor to promote hematopoietic stem cell self-renewal and transformation.
Academic Article Integrated transcriptional and competitive endogenous RNA networks are cross-regulated in permissive molecular environments.
Academic Article MicroRNA-antagonism regulates breast cancer stemness and metastasis via TET-family-dependent chromatin remodeling.
Academic Article From pseudo-ceRNAs to circ-ceRNAs: a tale of cross-talk and competition.
Academic Article Zbtb7a suppresses prostate cancer through repression of a Sox9-dependent pathway for cellular senescence bypass and tumor invasion.
Academic Article The RNA binding protein ESRP1 fine-tunes the expression of pluripotency-related factors in mouse embryonic stem cells.
Academic Article Noncoding RNAs and cancer.
Academic Article Pills of PTEN? In and out for tumor suppression.
Academic Article Synergy against PML-RARa: targeting transcription, proteolysis, differentiation, and self-renewal in acute promyelocytic leukemia.
Academic Article miR-22 in tumorigenesis.
Academic Article Designed transcription factors as structural, functional and therapeutic probes of chromatin in vivo. Fourth in review series on chromatin dynamics.
Academic Article HIF factors cooperate with PML-RARa to promote acute promyelocytic leukemia progression and relapse.
Academic Article The Lilliputians and the Giant: An Emerging Oncogenic microRNA Network that Suppresses the PTEN Tumor Suppressor In Vivo.
Academic Article Suppression of CHK1 by ETS Family Members Promotes DNA Damage Response Bypass and Tumorigenesis.
Academic Article In Vivo Role of INPP4B in Tumor and Metastasis Suppression through Regulation of PI3K-AKT Signaling at Endosomes.
Academic Article Active Pin1 is a key target of all-trans retinoic acid in acute promyelocytic leukemia and breast cancer.
Academic Article Suppression of T-cell lymphomagenesis in mice requires PTEN phosphatase activity.
Academic Article Distinct germline progenitor subsets defined through Tsc2-mTORC1 signaling.
Academic Article A genetic platform to model sarcomagenesis from primary adult mesenchymal stem cells.
Academic Article G-protein-coupled receptors regulate autophagy by ZBTB16-mediated ubiquitination and proteasomal degradation of Atg14L.
Academic Article ZBTB7A Suppresses Melanoma Metastasis by Transcriptionally Repressing MCAM.
Academic Article LRF maintains genome integrity by regulating the non-homologous end joining pathway of DNA repair.
Academic Article Stress from Nucleotide Depletion Activates the Transcriptional Regulator HEXIM1 to Suppress Melanoma.
Academic Article Posttranscriptional Regulation of PTEN by Competing Endogenous RNAs.
Academic Article PML at Mitochondria-Associated Membranes Is Critical for the Repression of Autophagy and Cancer Development.
Academic Article PHD3 Loss in Cancer Enables Metabolic Reliance on Fatty Acid Oxidation via Deactivation of ACC2.
Academic Article PML/RARa inhibits PTEN expression in hematopoietic cells by competing with PU.1 transcriptional activity.
Academic Article MCM7 and its hosted miR-25, 93 and 106b cluster elicit YAP/TAZ oncogenic activity in lung cancer.
Academic Article The RNA-binding protein ESRP1 promotes human colorectal cancer progression.
Academic Article Therapeutic inhibition of USP7-PTEN network in chronic lymphocytic leukemia: a strategy to overcome TP53 mutated/deleted clones.
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  • Gene Expression Regulation