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The DNA mismatch repair genes Msh3 and Msh6 cooperate in intestinal tumor suppression.
Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes.
DNA mismatch repair protein Msh6 is required for optimal levels of ultraviolet-B-induced apoptosis in primary mouse fibroblasts.
Mutation in the mismatch repair gene Msh6 causes cancer susceptibility.
Mouse models for human DNA mismatch-repair gene defects.
The distinct spectra of tumor-associated Apc mutations in mismatch repair-deficient Apc1638N mice define the roles of MSH3 and MSH6 in DNA repair and intestinal tumorigenesis.
DNA mismatch repair deficiency accelerates endometrial tumorigenesis in Pten heterozygous mice.
Role of the mismatch repair gene, Msh6, in suppressing genome instability and radiation-induced mutations.
Novel roles for MLH3 deficiency and TLE6-like amplification in DNA mismatch repair-deficient gastrointestinal tumorigenesis and progression.
An Msh2 point mutation uncouples DNA mismatch repair and apoptosis.
Distinct effects of the recurrent Mlh1G67R mutation on MMR functions, cancer, and meiosis.
DNA Mismatch Repair
Genotype directed therapy in murine mismatch repair deficient tumors.
Germline TP53 Mutations in Patients With Early-Onset Colorectal Cancer in the Colon Cancer Family Registry.
Mouse Models for Human Cancer
Inhibition of colorectal cancer genomic copy number alterations and chromosomal fragile site tumor suppressor FHIT and WWOX deletions by DNA mismatch repair.
DNA Mismatch Repair