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One or more keywords matched the following items that are connected to Papakostas, George
Item TypeName
Academic Article A description of next-step switching versus augmentation practices for outpatients with treatment-resistant major depressive disorder enrolled in an academic specialty clinic.
Academic Article A survey of antidepressant prescribing practices in major depression with comorbid attention-deficit hyperactivity disorder.
Academic Article Somatic symptoms in treatment-resistant depression.
Academic Article Serum cholesterol in treatment-resistant depression.
Academic Article Brain white-matter hyperintensities and treatment outcome in major depressive disorder.
Academic Article Comparing the rapidity of response during treatment of major depressive disorder with bupropion and the SSRIs: a pooled survival analysis of 7 double-blind, randomized clinical trials.
Academic Article Tolerability of modern antidepressants.
Academic Article Nortriptyline for treatment-resistant depression.
Academic Article Dopaminergic-based pharmacotherapies for depression.
Academic Article Continuation cognitive-behavioural therapy maintains attributional style improvement in depressed patients responding acutely to fluoxetine.
Academic Article Antidepressants for major depressive disorder and dysthymic disorder in patients with comorbid alcohol use disorders: a meta-analysis of placebo-controlled randomized trials.
Academic Article Treatment of major depressive disorder and dysthymic disorder with antidepressants in patients with comorbid opiate use disorders enrolled in methadone maintenance therapy: a meta-analysis.
Academic Article Functioning and interpersonal relationships as predictors of response in treatment-resistant depression.
Academic Article Treatment-resistant depression.
Academic Article Elevated cholesterol levels associated with nonresponse to fluoxetine treatment in major depressive disorder.
Academic Article Hopelessness and suicidal ideation in outpatients with treatment-resistant depression: prevalence and impact on treatment outcome.
Academic Article Psychiatric comorbidity as a predictor of clinical response to nortriptyline in treatment-resistant major depressive disorder.
Academic Article Effects of S-adenosylmethionine augmentation of serotonin-reuptake inhibitor antidepressants on cognitive symptoms of major depressive disorder.
Academic Article Consensus statement and research needs: the role of dopamine and norepinephrine in depression and antidepressant treatment.
Academic Article Managing partial response or nonresponse: switching, augmentation, and combination strategies for major depressive disorder.
Academic Article Escitalopram versus SNRI antidepressants in the acute treatment of major depressive disorder: integrative analysis of four double-blind, randomized clinical trials.
Academic Article Placebo-controlled, antidepressant clinical trials cannot be shortened to less than 4 weeks' duration: a pooled analysis of randomized clinical trials employing a diagnostic odds ratio-based approach.
Academic Article Efficacy of antidepressants for dysthymia: a meta-analysis of placebo-controlled randomized trials.
Academic Article Limitations of contemporary antidepressants: tolerability.
Academic Article Relative antidepressant efficacy of bupropion and the selective serotonin reuptake inhibitors in major depressive disorder: gender-age interactions.
Academic Article Predictors, moderators, and mediators (correlates) of treatment outcome in major depressive disorder.
Academic Article Initial treatment approaches for patients with major depressive disorder.
Academic Article Low-dose transdermal testosterone augmentation therapy improves depression severity in women.
Academic Article Pharmacologic and therapeutic strategies in treatment-resistant depression. Switching antidepressants vs. conventional augmentation strategies.
Academic Article Effects of S-adenosylmethionine augmentation of serotonin-reuptake inhibitor antidepressants on cognitive symptoms of major depressive disorder.
Academic Article Efficacy of antidepressants for late-life depression: a meta-analysis and meta-regression of placebo-controlled randomized trials.
Academic Article The efficacy, tolerability, and safety of contemporary antidepressants.
Academic Article International consensus statement on major depressive disorder.
Academic Article Anxious depression and early changes in the HAMD-17 anxiety-somatization factor items and antidepressant treatment outcome.
Academic Article Early improvements in anxiety, depression, and anger/hostility symptoms and response to antidepressant treatment.
Academic Article Testing anxious depression as a predictor and moderator of symptom improvement in major depressive disorder during treatment with escitalopram.
Academic Article A survey of prescribing preferences in the treatment of refractory depression: recent trends.
Academic Article Serum folate, vitamin B12, and homocysteine in major depressive disorder, Part 1: predictors of clinical response in fluoxetine-resistant depression.
Academic Article A meta-analysis of early sustained response rates between antidepressants and placebo for the treatment of major depressive disorder.
Academic Article Antidepressant dose reduction and the risk of relapse in major depressive disorder.
Academic Article Treatment-related adverse events and outcome in a clinical trial of fluoxetine for major depressive disorder.
Academic Article A meta-analysis of clinical trials comparing milnacipran, a serotonin--norepinephrine reuptake inhibitor, with a selective serotonin reuptake inhibitor for the treatment of major depressive disorder.
Academic Article A double-blind, randomized, pilot dose-finding study of maca root (L. meyenii) for the management of SSRI-induced sexual dysfunction.
Academic Article Cholesterol in mood and anxiety disorders: review of the literature and new hypotheses.
Academic Article Switching to bupropion in fluoxetine-resistant major depressive disorder.
Academic Article Efficacy of the sequential integration of psychotherapy and pharmacotherapy in major depressive disorder: a preliminary meta-analysis.
Academic Article Hopelessness as a predictor of non-response to fluoxetine in major depressive disorder.
Academic Article Are antidepressant drugs that combine serotonergic and noradrenergic mechanisms of action more effective than the selective serotonin reuptake inhibitors in treating major depressive disorder? A meta-analysis of studies of newer agents.
Academic Article S-adenosyl methionine (SAMe) augmentation of serotonin reuptake inhibitors for antidepressant nonresponders with major depressive disorder: a double-blind, randomized clinical trial.
Academic Article Evidence for S-adenosyl-L-methionine (SAM-e) for the treatment of major depressive disorder.
Academic Article Relationship between probability of receiving placebo and probability of prematurely discontinuing treatment in double-blind, randomized clinical trials for MDD: a meta-analysis.
Academic Article Correlation between different levels of placebo response rate and clinical trial outcome in major depressive disorder: a meta-analysis.
Academic Article A double-blind dose-finding pilot study of docosahexaenoic acid (DHA) for major depressive disorder.
Academic Article Antidepressants for major depressive disorder in patients with a co-morbid axis-III disorder: a meta-analysis of patient characteristics and placebo response rates in randomized controlled trials.
Academic Article Switching, combination, and augmentation strategies for major depressive disorder.
Academic Article S-adenosyl-methionine in depression: a comprehensive review of the literature.
Academic Article Prevalence of MTHFR C677T and MS A2756G polymorphisms in major depressive disorder, and their impact on response to fluoxetine treatment.
Academic Article Empirical testing of two models for staging antidepressant treatment resistance.
Academic Article The combination of duloxetine and bupropion for treatment-resistant major depressive disorder.
Academic Article A cross-sectional study of the prevalence of cognitive and physical symptoms during long-term antidepressant treatment.
Academic Article Axis III disorders in treatment-resistant major depressive disorder.
Academic Article Does the presence of an open-label antidepressant treatment period influence study outcome in clinical trials examining augmentation/combination strategies in treatment partial responders/nonresponders with major depressive disorder?
Academic Article Folates and S-adenosylmethionine for major depressive disorder.
Academic Article Symptoms of fatigue and sleepiness in major depressive disorder.
Academic Article Efficacy of bupropion and the selective serotonin reuptake inhibitors in the treatment of anxiety symptoms in major depressive disorder: a meta-analysis of individual patient data from 10 double-blind, randomized clinical trials.
Academic Article Treatment-resistant depression and Axis II comorbidity.
Academic Article Cost-effectiveness of adjunctive therapy with atypical antipsychotics for acute treatment of major depressive disorder.
Academic Article The relationship between serum folate, vitamin B12, and homocysteine levels in major depressive disorder and the timing of improvement with fluoxetine.
Academic Article Psychosocial functioning during the treatment of major depressive disorder with fluoxetine.
Academic Article Augmentation of standard antidepressants with atypical antipsychotic agents for treatment-resistant major depressive disorder.
Academic Article A meta-analysis of clinical trials comparing mirtazapine with selective serotonin reuptake inhibitors for the treatment of major depressive disorder.
Academic Article Complementary and alternative medicine for major depressive disorder: a meta-analysis of patient characteristics, placebo-response rates, and treatment outcomes relative to standard antidepressants.
Academic Article Surrogate markers of treatment outcome in major depressive disorder.
Academic Article Problem-solving ability and comorbid personality disorders in depressed outpatients.
Academic Article SAMe and sexual functioning.
Academic Article Does the probability of receiving placebo influence clinical trial outcome? A meta-regression of double-blind, randomized clinical trials in MDD.
Academic Article Obesity among outpatients with major depressive disorder.
Academic Article Psychic and somatic anxiety symptoms as predictors of response to fluoxetine in major depressive disorder.
Academic Article Psychosocial functioning in patients with treatment resistant depression.
Academic Article Augmentation of antidepressants with atypical antipsychotics for treatment-resistant major depressive disorder.
Academic Article Fluoxetine-clonazepam cotherapy for anxious depression: an exploratory, post-hoc analysis of a randomized, double blind study.
Academic Article Lithium augmentation of nortriptyline for subjects resistant to multiple antidepressants.
Academic Article A pilot, open study of sertraline in outpatients with treatment-resistant depression (TRD) or with a history of TRD who responded but later relapsed.
Academic Article Augmentation of antidepressants with atypical antipsychotic medications for treatment-resistant major depressive disorder: a meta-analysis.
Academic Article Augmentation strategies in the treatment of major depressive disorder. Examining the evidence on augmentation with atypical antipsychotics.
Academic Article Efficacy of dose increase among nonresponders to low-dose aripiprazole augmentation in patients with inadequate response to antidepressant treatment: a randomized, double-blind, placebo-controlled, efficacy trial.
Concept Antidepressive Agents
Concept Antidepressive Agents, Second-Generation
Concept Antidepressive Agents, Tricyclic
Academic Article Efficacy of desvenlafaxine 50 mg compared with placebo in patients with moderate or severe major depressive disorder: a pooled analysis of six randomized, double-blind, placebo-controlled studies.
Academic Article Resolution of sleepiness and fatigue: a comparison of bupropion and selective serotonin reuptake inhibitors in subjects with major depressive disorder achieving remission at doses approved in the European Union.
Academic Article Does the frequency of follow-up assessments affect clinical trial outcome? A meta-analysis and meta-regression of placebo-controlled randomized trials.
Academic Article A double-blind, randomized, placebo-controlled clinical trial of S-adenosyl-L-methionine (SAMe) versus escitalopram in major depressive disorder.
Academic Article S-adenosyl methionine (SAMe) versus escitalopram and placebo in major depression RCT: efficacy and effects of histamine and carnitine as moderators of response.
Academic Article Dr. Mischoulon and colleagues reply.
Academic Article An overview of vortioxetine.
Academic Article Updates and trends in the treatment of major depressive disorder.
Academic Article Understanding and managing Cognition in the Depressed Patient.
Academic Article The nature of placebo response in clinical studies of major depressive disorder.
Academic Article Efficacy of ziprasidone monotherapy in patients with anxious depression: a 12-week, randomized, double-blind, placebo-controlled, sequential-parallel comparison trial.
Academic Article Predictors of placebo response in bipolar depression.
Academic Article Is S-Adenosyl Methionine (SAMe) for Depression Only Effective in Males? A Re-Analysis of Data from a Randomized Clinical Trial.
Academic Article Influence of anxiety symptoms on improvement of neurocognitive functions in patients with major depressive disorder: A 12-week, multicenter, randomized trial of tianeptine versus escitalopram, the CAMPION study.
Academic Article Antidepressants and their effect on cognition in major depressive disorder.
Academic Article Ziprasidone Augmentation of Escitalopram for Major Depressive Disorder: Efficacy Results From a Randomized, Double-Blind, Placebo-Controlled Study.
Academic Article Identifying patients with depression who require a change in treatment and implementing that change.
Academic Article Demographic variables, design characteristics, and effect sizes of randomized, placebo-controlled, monotherapy trials of major depressive disorder and bipolar depression.
Academic Article Adjunctive Nutraceuticals for Depression: A Systematic Review and Meta-Analyses.
Academic Article Identifying Patients Who Need a Change in Depression Treatment and Implementing That Change.
Grant S-Adenosyl Methionine(SAMe)Augmentation of SSRIs in MDD
Grant 1/2-Ziprasidone Augmentation of SSRIs for Treatment-Resistant Depression (TRD)
Academic Article Ziprasidone augmentation for anxious depression.
Academic Article Experimental medication treatment approaches for depression.
Academic Article Double-blind, proof-of-concept (POC) trial of Low-Field Magnetic Stimulation (LFMS) augmentation of antidepressant therapy in treatment-resistant depression (TRD).
Academic Article Double-blind, placebo-controlled, dose-ranging trial of intravenous ketamine as adjunctive therapy in treatment-resistant depression (TRD).
Academic Article Tachyphylaxis in major depressive disorder: A review of the current state of research.
Academic Article Sex differences in response to ketamine as a rapidly acting intervention for treatment resistant depression.
Academic Article Staging Treatment Intensity and Defining Resistant Depression: Historical Overview and Future Directions.
Academic Article Ratio of plasma BDNF to leptin levels are associated with treatment response in major depressive disorder but not in panic disorder: A 12-week follow-up study.
Academic Article Success and efficiency of phase 2/3 adjunctive trials for MDD funded by industry: a systematic review.
Academic Article Maintaining Rapid Antidepressant Effects Following Ketamine Infusion: A Major Unmet Need.
Academic Article Improvement of sexual functioning during treatment of MDD with adjunctive pimavanserin: A secondary analysis.
Academic Article Implementing Measurement-Based Care to Determine and Treat Inadequate Response.
Academic Article Recognizing Inadequate Response in Patients With Major Depressive Disorder.
Academic Article Inadequate Response to Treatment in Major Depressive Disorder: Augmentation and Adjunctive Strategies.
Academic Article Inadequate Response to Antidepressant Treatment in Major Depressive Disorder.
Academic Article Overcoming Challenges to Treat Inadequate Response in Major Depressive Disorder.
Academic Article Efficacy of Esketamine Augmentation in Major Depressive Disorder: A Meta-Analysis.
Academic Article Effect of pimavanserin on anxious depression in patients with major depression and an inadequate response to previous therapy: secondary analysis of the clarity study.
Academic Article Effect of Adjunctive Pimavanserin on Sleep/Wakefulness in Patients With Major Depressive Disorder: Secondary Analysis From CLARITY.
Academic Article Impact of Supplementation and Nutritional Interventions on Pathogenic Processes of Mood Disorders: A Review of the Evidence.
Academic Article Synthesizing the Evidence for Ketamine and Esketamine in Treatment-Resistant Depression: An International Expert Opinion on the Available Evidence and Implementation.
Academic Article Vortioxetine Versus Placebo for Major Depressive Disorder: A Comprehensive Analysis of the Clinical Trial Dataset.
Search Criteria
  • Antidepressive Agents
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.