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One or more keywords matched the following items that are connected to Polyak, Kornelia
Item TypeName
Academic Article Genetic determinants of p53-induced apoptosis and growth arrest.
Academic Article Identifying tumor origin using a gene expression-based classification map.
Academic Article Somatic mutations of the mitochondrial genome in human colorectal tumours.
Academic Article Breast cancer gene discovery.
Academic Article Very high frequency of hypermethylated genes in breast cancer metastasis to the bone, brain, and lung.
Academic Article 14-3-3sigma is a p53-regulated inhibitor of G2/M progression.
Academic Article Pregnancy and breast cancer: the other side of the coin.
Academic Article Gene discovery using the serial analysis of gene expression technique: implications for cancer research.
Academic Article Molecular alterations in ductal carcinoma in situ of the breast.
Academic Article Identification of CD44v6(+)/CD24- breast carcinoma cells in primary human tumors by quantum dot-conjugated antibodies.
Academic Article Is p53 a breast cancer gene?
Academic Article EMSY links breast cancer gene 2 to the 'Royal Family'.
Academic Article DNA methylation of RASSF1A, HIN-1, RAR-beta, Cyclin D2 and Twist in in situ and invasive lobular breast carcinoma.
Academic Article Phenol sulfotransferases: hormonal regulation, polymorphism, and age of onset of breast cancer.
Academic Article Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma.
Academic Article A public database for gene expression in human cancers.
Academic Article Do myoepithelial cells hold the key for breast tumor progression?
Academic Article p53-dependent expression of PIG3 during proliferation, genotoxic stress, and reversible growth arrest.
Academic Article A putative role for psoriasin in breast tumor progression.
Academic Article Molecular definition of breast tumor heterogeneity.
Academic Article Breast tumor heterogeneity: cancer stem cells or clonal evolution?
Academic Article Is breast tumor progression really linear?
Academic Article S100A7-downregulation inhibits epidermal growth factor-induced signaling in breast cancer cells and blocks osteoclast formation.
Academic Article Breast-cancer stromal cells with TP53 mutations.
Academic Article Genome-wide functional synergy between amplified and mutated genes in human breast cancer.
Academic Article Regulation of in situ to invasive breast carcinoma transition.
Academic Article Molecular markers in ductal carcinoma in situ of the breast.
Academic Article Serial analysis of gene expression of lobular carcinoma in situ identifies down regulation of claudin 4 and overexpression of matrix metalloproteinase 9.
Academic Article Mesenchymal stem cells within tumour stroma promote breast cancer metastasis.
Academic Article Distinct epigenetic changes in the stromal cells of breast cancers.
Academic Article HIN-1, an inhibitor of cell growth, invasion, and AKT activation.
Academic Article No evidence of clonal somatic genetic alterations in cancer-associated fibroblasts from human breast and ovarian carcinomas.
Academic Article Role of COX-2 in epithelial-stromal cell interactions and progression of ductal carcinoma in situ of the breast.
Academic Article Control of cyclin D1 and breast tumorigenesis by the EglN2 prolyl hydroxylase.
Academic Article CDX2 is mutated in a colorectal cancer with normal APC/beta-catenin signaling.
Academic Article Progress in breast cancer research.
Academic Article The JAK2/STAT3 signaling pathway is required for growth of CD44?CD24? stem cell-like breast cancer cells in human tumors.
Academic Article An anatomy of normal and malignant gene expression.
Academic Article Cancer target discovery using SAGE.
Academic Article Epigenetic patterns of embryonic and adult stem cells.
Academic Article Molecular markers for the diagnosis and management of ductal carcinoma in situ.
Academic Article The origins and implications of intratumor heterogeneity.
Academic Article Cellular heterogeneity and molecular evolution in cancer.
Academic Article A neural survival factor is a candidate oncogene in breast cancer.
Academic Article The p27Kip1 tumor suppressor gene: Still a suspect or proven guilty?
Academic Article Lack of HIN-1 methylation in BRCA1-linked and "BRCA1-like" breast tumors.
Academic Article Ductal carcinoma in situ of the breast.
Academic Article Cancer chromosomes in crisis.
Academic Article Combined cDNA array comparative genomic hybridization and serial analysis of gene expression analysis of breast tumor progression.
Academic Article Functional synergies yet distinct modulators affected by genetic alterations in common human cancers.
Academic Article HIN-1, a putative cytokine highly expressed in normal but not cancerous mammary epithelial cells.
Academic Article Cellular and molecular targets of estrogen in normal human breast tissue.
Academic Article Tumor heterogeneity: causes and consequences.
Academic Article Molecular characterization of the tumor microenvironment in breast cancer.
Academic Article Gene expression profiling of human breast tissue samples using SAGE-Seq.
Academic Article Contribution of bone marrow-derived endothelial cells to human tumor vasculature.
Academic Article Expression of the human mismatch repair gene hMSH2 in normal and neoplastic tissues.
Academic Article Breast cancer: origins and evolution.
Academic Article Molecular characterisation of the tumour microenvironment in breast cancer.
Academic Article Targeting the missing links for cancer therapy.
Academic Article Intra-tumour heterogeneity: a looking glass for cancer?
Academic Article A blueprint for an international cancer epigenome consortium. A report from the AACR Cancer Epigenome Task Force.
Academic Article PAK1 is a breast cancer oncogene that coordinately activates MAPK and MET signaling.
Academic Article The cancer stem cell hypothesis: in search of definitions, markers, and relevance.
Academic Article Heterogeneity for stem cell-related markers according to tumor subtype and histologic stage in breast cancer.
Academic Article Stem cells in the human breast.
Academic Article The challenges posed by cancer heterogeneity.
Academic Article SnapShot: breast cancer.
Academic Article Analysis of human transcriptomes.
Academic Article A SAGE (serial analysis of gene expression) view of breast tumor progression.
Academic Article A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice.
Academic Article Breast cancer stem cells: a case of mistaken identity?
Academic Article On the birth of breast cancer.
Academic Article Novel estrogen and tamoxifen induced genes identified by SAGE (Serial Analysis of Gene Expression).
Academic Article The hairy powers of oncogenes: from biological function to cancer therapy.
Academic Article Estrogen receptor/progesterone receptor-negative breast cancers of young African-American women have a higher frequency of methylation of multiple genes than those of Caucasian women.
Academic Article Frequent HIN-1 promoter methylation and lack of expression in multiple human tumor types.
Academic Article Cancer stem cells: a model in the making.
Academic Article Clonal mutations in the cancer-associated fibroblasts: the case against genetic coevolution.
Academic Article Knock in of the AKT1 E17K mutation in human breast epithelial cells does not recapitulate oncogenic PIK3CA mutations.
Academic Article Somatic mutations in the Notch, NF-KB, PIK3CA, and Hedgehog pathways in human breast cancers.
Academic Article p27Kip1: chromosomal mapping to 12p12-12p13.1 and absence of mutations in human tumors.
Academic Article On chromatin remodeling in mammary gland differentiation and breast tumorigenesis.
Academic Article The microenvironment in breast cancer progression: biology and implications for treatment.
Academic Article Cancer. Cancer cell phenotypes, in fifty shades of grey.
Academic Article SAGE and related approaches for cancer target identification.
Academic Article PIK3CA mutations in in situ and invasive breast carcinomas.
Academic Article Cyclins, Cdks, and cyclin kinase inhibitors.
Academic Article Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state.
Academic Article Unraveling the complexity of basal-like breast cancer.
Academic Article Evolutionary pathways in BRCA1-associated breast tumors.
Academic Article Epithelial and stromal cathepsin K and CXCL14 expression in breast tumor progression.
Academic Article Integrative genomic approaches identify IKBKE as a breast cancer oncogene.
Academic Article Microenvironmental regulation of cancer development.
Academic Article Sequence analysis of mutations and translocations across breast cancer subtypes.
Academic Article Cellular and genetic diversity in the progression of in situ human breast carcinomas to an invasive phenotype.
Academic Article The role of the microenvironment in mammary gland development and cancer.
Academic Article Heterogeneity in breast cancer.
Academic Article On using functional genetics to understand breast cancer biology.
Academic Article Early alteration of cell-cycle-regulated gene expression in colorectal neoplasia.
Academic Article Altered antisense-to-sense transcript ratios in breast cancer.
Academic Article Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits.
Academic Article Profiling critical cancer gene mutations in clinical tumor samples.
Academic Article Roots and stems: stem cells in cancer.
Academic Article The genomic landscapes of human breast and colorectal cancers.
Academic Article An intraductal human-in-mouse transplantation model mimics the subtypes of ductal carcinoma in situ.
Academic Article Psoriasin expression in mammary epithelial cells in vitro and in vivo.
Academic Article Cyclooxygenase-2 expression during immortalization and breast cancer progression.
Concept Colonic Neoplasms
Concept Breast Neoplasms
Concept Bone Neoplasms
Concept Colorectal Neoplasms
Concept Cancer Vaccines
Concept Pancreatic Neoplasms
Concept Ovarian Neoplasms
Concept Pituitary Neoplasms
Concept Mammary Neoplasms, Animal
Concept Mammary Neoplasms, Experimental
Concept Esophageal Neoplasms
Concept Brain Neoplasms
Concept Lung Neoplasms
Concept Neoplasms
Concept Lymphatic Metastasis
Concept Uterine Cervical Neoplasms
Concept Prostatic Neoplasms
Concept Neoplasm Metastasis
Academic Article RNA sequencing of cancer reveals novel splicing alterations.
Academic Article Molecular profiling of human mammary gland links breast cancer risk to a p27(+) cell population with progenitor characteristics.
Academic Article Methylation-specific digital karyotyping of HPV16E6E7-expressing human keratinocytes identifies novel methylation events in cervical carcinogenesis.
Academic Article Deconvoluting complex tissues for expression quantitative trait locus-based analyses.
Academic Article The RasGAP gene, RASAL2, is a tumor and metastasis suppressor.
Academic Article Glutamine sensitivity analysis identifies the xCT antiporter as a common triple-negative breast tumor therapeutic target.
Academic Article Targeting Akt3 signaling in triple-negative breast cancer.
Academic Article Tracking tumor resistance using 'liquid biopsies'.
Academic Article Inference of tumor evolution during chemotherapy by computational modeling and in situ analysis of genetic and phenotypic cellular diversity.
Academic Article Genetic and phenotypic diversity in breast tumor metastases.
Academic Article Tumor heterogeneity confounds and illuminates: a case for Darwinian tumor evolution.
Academic Article Cancer: Clonal cooperation.
Academic Article Oncogene-like induction of cellular invasion from centrosome amplification.
Academic Article JARID1B is a luminal lineage-driving oncogene in breast cancer.
Academic Article Tumor heterogeneity: the Lernaean hydra of oncology?
Academic Article Non-cell-autonomous driving of tumour growth supports sub-clonal heterogeneity.
Academic Article MSC-regulated microRNAs converge on the transcription factor FOXP2 and promote breast cancer metastasis.
Academic Article Clonal evolution in cancer: a tale of twisted twines.
Academic Article Dermcidin exerts its oncogenic effects in breast cancer via modulation of ERBB signaling.
Academic Article CLK2 Is an Oncogenic Kinase and Splicing Regulator in Breast Cancer.
Academic Article Somatic Cell Fusions Reveal Extensive Heterogeneity in Basal-like Breast Cancer.
Academic Article Tumorigenesis: it takes a village.
Academic Article Combining miR-10b-Targeted Nanotherapy with Low-Dose Doxorubicin Elicits Durable Regressions of Metastatic Breast Cancer.
Academic Article HOXB7 Is an ERa Cofactor in the Activation of HER2 and Multiple ER Target Genes Leading to Endocrine Resistance.
Academic Article In situ single-cell analysis identifies heterogeneity for PIK3CA mutation and HER2 amplification in HER2-positive breast cancer.
Academic Article Principles Governing A-to-I RNA Editing in the Breast Cancer Transcriptome.
Academic Article Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer.
Academic Article Intratumor Heterogeneity in Breast Cancer.
Academic Article The Proliferative Activity of Mammary Epithelial Cells in Normal Tissue Predicts Breast Cancer Risk in Premenopausal Women.
Academic Article BRCA1/FANCD2/BRG1-Driven DNA Repair Stabilizes the Differentiation State of Human Mammary Epithelial Cells.
Academic Article Direct Transcriptional Consequences of Somatic Mutation in Breast Cancer.
Grant Dana-Farber/Harvard Cancer Center SPORE in Breast Cancer
Grant Targeting intratumor heterogeneity in breast cancer
Grant Intratumor heterogeneity underlying treatment resistance in HER2+ breast tumors
Grant HIN-1,A Novel Putative Breast Tumor Suppressor Gene
Grant Dana-Farber/Harvard SPORE in Breast Cancer
Grant Epithelial-stromal cell interactions in breast cancer
Academic Article Spatial Proximity to Fibroblasts Impacts Molecular Features and Therapeutic Sensitivity of Breast Cancer Cells Influencing Clinical Outcomes.
Academic Article BET Bromodomain Proteins as Cancer Therapeutic Targets.
Academic Article Expression of estrogen receptor, progesterone receptor, and Ki67 in normal breast tissue in relation to subsequent risk of breast cancer.
Academic Article Mathematical Modeling Links Pregnancy-Associated Changes and Breast Cancer Risk.
Academic Article Precancer Atlas to Drive Precision Prevention Trials.
Academic Article Cell-Cycle-Targeting MicroRNAs as Therapeutic Tools against Refractory Cancers.
Academic Article The metabolic function of cyclin D3-CDK6 kinase in cancer cell survival.
Academic Article Immune Escape in Breast Cancer During In Situ to Invasive Carcinoma Transition.
Academic Article Classifying the evolutionary and ecological features of neoplasms.
Academic Article Myoepithelial cell-specific expression of stefin A as a suppressor of early breast cancer invasion.
Academic Article Scientific Summary from the Morgan Welch MD Anderson Cancer Center Inflammatory Breast Cancer (IBC) Program 10th Anniversary Conference.
Academic Article Phase II study of ruxolitinib, a selective JAK1/2 inhibitor, in patients with metastatic triple-negative breast cancer.
Academic Article Intratumor heterogeneity defines treatment-resistant HER2+ breast tumors.
Academic Article TRPS1 Is a Lineage-Specific Transcriptional Dependency in Breast Cancer.
Academic Article KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance.
Academic Article Epidemiology, Biology, Treatment, and Prevention of Ductal Carcinoma In Situ (DCIS).
Academic Article Insights into Molecular Classifications of Triple-Negative Breast Cancer: Improving Patient Selection for Treatment.
Academic Article KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance.
Academic Article Intratumoral Heterogeneity: More Than Just Mutations.
Academic Article Deletion of Cdkn1b in ACI rats leads to increased proliferation and pregnancy-associated changes in the mammary gland due to perturbed systemic endocrine environment.
Academic Article Metastasis as a systemic disease: molecular insights and clinical implications.
Academic Article EN1 Is a Transcriptional Dependency in Triple-Negative Breast Cancer Associated with Brain Metastasis.
Academic Article Subclonal cooperation drives metastasis by modulating local and systemic immune microenvironments.
Academic Article Tumor Neoantigens: When Too Much of a Good Thing Is Bad.
Academic Article Immune Escape during Breast Tumor Progression.
Academic Article Premenopausal Plasma Osteoprotegerin and Breast Cancer Risk: A Case-Control Analysis Nested within the Nurses' Health Study II.
Academic Article Intratumor Heterogeneity: The Rosetta Stone of Therapy Resistance.
Academic Article Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.
Academic Article Acquired resistance to combined BET and CDK4/6 inhibition in triple-negative breast cancer.
Academic Article Increased lysosomal biomass is responsible for the resistance of triple-negative breast cancers to CDK4/6 inhibition.
Grant New therapeutic vulnerabilities in breast cancer
Academic Article Early-Life Body Adiposity and the Breast Tumor Transcriptome.
Academic Article Genomic Alterations during the In Situ to Invasive Ductal Breast Carcinoma Transition Shaped by the Immune System.
Academic Article Identifying key questions in the ecology and evolution of cancer.
Academic Article The impact of tumor epithelial and microenvironmental heterogeneity on treatment responses in HER2+ breast cancer.
Academic Article Impact of HER2 Heterogeneity on Treatment Response of Early-Stage HER2-Positive Breast Cancer: Phase II Neoadjuvant Clinical Trial of T-DM1 Combined with Pertuzumab.
Academic Article The MCF10 Model of Breast Tumor Progression.
Search Criteria
  • Cancer
  • metastasis
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.