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One or more keywords matched the following items that are connected to Alt, Frederick
Item TypeName
Academic Article Gene-targeted deletion and replacement mutations of the T-cell receptor beta-chain enhancer: the role of enhancer elements in controlling V(D)J recombination accessibility.
Academic Article Promotion of V(D)J recombinational accessibility by the intronic E kappa element: role of the kappa B motif.
Academic Article Mechanisms that direct ordered assembly of T cell receptor beta locus V, D, and J gene segments.
Academic Article Impaired viability and profound block in thymocyte development in mice lacking the adaptor protein SLP-76.
Academic Article Extrachromosomal recombination substrates recapitulate beyond 12/23 restricted VDJ recombination in nonlymphoid cells.
Academic Article E mu N- and E mu L-myc cooperate with E mu pim-1 to generate lymphoid tumors at high frequency in double-transgenic mice.
Academic Article Separate elements control DJ and VDJ rearrangement in a transgenic recombination substrate.
Academic Article Dramatically increased rearrangement and peripheral representation of Vbeta14 driven by the 3'Dbeta1 recombination signal sequence.
Academic Article Productive coupling of accessible Vbeta14 segments and DJbeta complexes determines the frequency of Vbeta14 rearrangement.
Academic Article Vbeta cluster sequences reduce the frequency of primary Vbeta2 and Vbeta14 rearrangements.
Academic Article Differential activation of transcription versus recombination of transgenic T cell receptor beta variable region gene segments in B and T lineage cells.
Academic Article Restriction of endogenous T cell antigen receptor beta rearrangements to Vbeta14 through selective recombination signal sequence modifications.
Academic Article Fc gamma RII/III and CD2 expression mark distinct subpopulations of immature CD4-CD8- murine thymocytes: in vivo developmental kinetics and T cell receptor beta chain rearrangement status.
Concept Gene Rearrangement, beta-Chain T-Cell Antigen Receptor
Search Criteria
  • Gene Rearrangement beta Chain T Cell Antigen Receptor
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.