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One or more keywords matched the following items that are connected to Kulkarni, Rohit
Item TypeName
Academic Article Melanin-concentrating hormone overexpression in transgenic mice leads to obesity and insulin resistance.
Academic Article Orphan receptor small heterodimer partner is an important mediator of glucose homeostasis.
Academic Article Possible evidence for endogenous production of a novel galanin-like peptide.
Academic Article cAMP promotes pancreatic beta-cell survival via CREB-mediated induction of IRS2.
Academic Article Reduced beta-cell mass and altered glucose sensing impair insulin-secretory function in betaIRKO mice.
Academic Article Upregulation of insulin receptor substrate-2 in pancreatic beta cells prevents diabetes.
Academic Article Loss of ARNT/HIF1beta mediates altered gene expression and pancreatic-islet dysfunction in human type 2 diabetes.
Academic Article Characterization of multiple signaling pathways of insulin in the regulation of vascular endothelial growth factor expression in vascular cells and angiogenesis.
Academic Article Alterations in growth and apoptosis of insulin receptor substrate-1-deficient beta-cells.
Academic Article Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunction.
Academic Article A model to explore the interaction between muscle insulin resistance and beta-cell dysfunction in the development of type 2 diabetes.
Academic Article Exogenous insulin enhances glucose-stimulated insulin response in healthy humans independent of changes in free fatty acids.
Academic Article Total insulin and IGF-I resistance in pancreatic beta cells causes overt diabetes.
Academic Article Evidence for a circulating islet cell growth factor in insulin-resistant states.
Academic Article The islet beta-cell.
Academic Article Roles for leptin receptor/STAT3-dependent and -independent signals in the regulation of glucose homeostasis.
Academic Article Melanin concentrating hormone is a novel regulator of islet function and growth.
Academic Article Insulin receptors in beta-cells are critical for islet compensatory growth response to insulin resistance.
Academic Article Characterization of the mouse pancreatic islet proteome and comparative analysis with other mouse tissues.
Academic Article New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure.
Academic Article Retraction. Orphan receptor small heterodimer partner is an important mediator of glucose homeostasis.
Academic Article TRB3 links the E3 ubiquitin ligase COP1 to lipid metabolism.
Academic Article Gene silencing of phogrin unveils its essential role in glucose-responsive pancreatic beta-cell growth.
Academic Article Glucagon-like peptide-1 increases beta-cell glucose competence and proliferation by translational induction of insulin-like growth factor-1 receptor expression.
Academic Article Disruption of leptin receptor expression in the pancreas directly affects beta cell growth and function in mice.
Academic Article Pyroglutamyl-phenylalanyl-proline amide attenuates thyrotropin-releasing hormone-stimulated insulin secretion in perifused rat islets and insulin-secreting clonal beta-cell lines.
Academic Article Insulin signaling in alpha cells modulates glucagon secretion in vivo.
Academic Article Mutations at the BLK locus linked to maturity onset diabetes of the young and beta-cell dysfunction.
Academic Article The roles of telomeres and telomerase in beta-cell regeneration.
Academic Article Accurate measurement of pancreatic islet beta-cell mass using a second-generation fluorescent exendin-4 analog.
Academic Article Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1.
Academic Article Knockout mice challenge our concepts of glucose homeostasis and the pathogenesis of diabetes mellitus.
Academic Article Insulin signaling regulates mitochondrial function in pancreatic beta-cells.
Academic Article Rosiglitazone promotes PPAR?-dependent and -independent alterations in gene expression in mouse islets.
Academic Article Islet secretory defect in insulin receptor substrate 1 null mice is linked with reduced calcium signaling and expression of sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA)-2b and -3.
Academic Article Aquaporin 7 is a beta-cell protein and regulator of intraislet glycerol content and glycerol kinase activity, beta-cell mass, and insulin production and secretion.
Academic Article Receptors for insulin and insulin-like growth factor-1 and insulin receptor substrate-1 mediate pathways that regulate islet function.
Academic Article Regulation of vascular endothelial growth factor expression and vascularization in the myocardium by insulin receptor and PI3K/Akt pathways in insulin resistance and ischemia.
Academic Article Skeletal muscle-selective knockout of LKB1 increases insulin sensitivity, improves glucose homeostasis, and decreases TRB3.
Academic Article Regulation of calcium-permeable TRPV2 channel by insulin in pancreatic beta-cells.
Academic Article Glucose effects on beta-cell growth and survival require activation of insulin receptors and insulin receptor substrate 2.
Academic Article Near-infrared fluorescent probe for imaging of pancreatic beta cells.
Academic Article Molecular biology. HNFs--linking the liver and pancreatic islets in diabetes.
Academic Article Molecular approaches to study control of glucose homeostasis.
Academic Article Glibenclamide but not other sulphonylureas stimulates release of neuropeptide Y from perifused rat islets and hamster insulinoma cells.
Academic Article Impact of genetic background on development of hyperinsulinemia and diabetes in insulin receptor/insulin receptor substrate-1 double heterozygous mice.
Academic Article The pseudokinase tribbles homolog 3 interacts with ATF4 to negatively regulate insulin exocytosis in human and mouse beta cells.
Academic Article Ephs and ephrins keep pancreatic Beta cells connected.
Academic Article Wnt signaling: relevance to beta-cell biology and diabetes.
Academic Article Abnormal glucose homeostasis in skeletal muscle-specific PGC-1alpha knockout mice reveals skeletal muscle-pancreatic beta cell crosstalk.
Academic Article Ablation of TRIP-Br2, a regulator of fat lipolysis, thermogenesis and oxidative metabolism, prevents diet-induced obesity and insulin resistance.
Academic Article Hypoxia-inducible factor-1alpha regulates beta cell function in mouse and human islets.
Academic Article ?40 Isoform of p53 controls ß-cell proliferation and glucose homeostasis in mice.
Academic Article Leptin rapidly suppresses insulin release from insulinoma cells, rat and human islets and, in vivo, in mice.
Academic Article Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes.
Academic Article Targeted elimination of peroxisome proliferator-activated receptor gamma in beta cells leads to abnormalities in islet mass without compromising glucose homeostasis.
Academic Article Liver-derived systemic factors drive ß cell hyperplasia in insulin-resistant states.
Academic Article Tissue-specific targeting of the insulin receptor gene.
Academic Article Altered function of insulin receptor substrate-1-deficient mouse islets and cultured beta-cell lines.
Academic Article Glucose homeostasis and tissue transcript content of insulin signaling intermediates in four inbred strains of mice: C57BL/6, C57BLKS/6, DBA/2, and 129X1.
Academic Article PDX-1 haploinsufficiency limits the compensatory islet hyperplasia that occurs in response to insulin resistance.
Academic Article New insights into the roles of insulin/IGF-I in the development and maintenance of beta-cell mass.
Academic Article Investigation of the effects of antisense oligodeoxynucleotides to islet amyloid polypeptide mRNA on insulin release, content and expression.
Academic Article Carcinoembryonic antigen-related cell adhesion molecule 1: a link between insulin and lipid metabolism.
Academic Article A 67 kDa protein mediates pituitary adenylate cyclase-activating polypeptide and vasoactive intestinal peptide-stimulated insulin secretion in a hamster clonal beta-cell line.
Academic Article GCK-MODY diabetes associated with protein misfolding, cellular self-association and degradation.
Academic Article Roles of insulin receptor substrate-1, phosphatidylinositol 3-kinase, and release of intracellular Ca2+ stores in insulin-stimulated insulin secretion in beta -cells.
Academic Article Lessons for human diabetes from experimental mouse models.
Academic Article Identification of interactive loci linked to insulin and leptin in mice with genetic insulin resistance.
Academic Article Altered insulin receptor signalling and ß-cell cycle dynamics in type 2 diabetes mellitus.
Academic Article Mouse-specific tandem IgY7-SuperMix immunoaffinity separations for improved LC-MS/MS coverage of the plasma proteome.
Academic Article Pancreatic function in carboxyl-ester lipase knockout mice.
Academic Article Modulation of ß-cell function: a translational journey from the bench to the bedside.
Academic Article Growth factor control of pancreatic islet regeneration and function.
Academic Article Differential expression of cell cycle proteins during ageing of pancreatic islet cells.
Academic Article Insulin enhances glucose-stimulated insulin secretion in healthy humans.
Academic Article PGC-1 promotes insulin resistance in liver through PPAR-alpha-dependent induction of TRB-3.
Academic Article Selective insulin signaling through A and B insulin receptors regulates transcription of insulin and glucokinase genes in pancreatic beta cells.
Academic Article Effect of the insulin mimetic L-783,281 on intracellular Ca2+ and insulin secretion from pancreatic beta-cells.
Academic Article beta-cell-specific deletion of the Igf1 receptor leads to hyperinsulinemia and glucose intolerance but does not alter beta-cell mass.
Academic Article Knockout models are useful tools to dissect the pathophysiology and genetics of insulin resistance.
Academic Article Lipoatrophic diabetes in Irs1(-/-)/Irs3(-/-) double knockout mice.
Academic Article TRB3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver.
Academic Article Uncoupling modifier genes from uncoupling protein 2 in pancreatic beta-cells.
Academic Article High glucose inhibits glucose-6-phosphate dehydrogenase, leading to increased oxidative stress and beta-cell apoptosis.
Academic Article Inhibition of glucose stimulated insulin secretion by neuropeptide Y is mediated via the Y1 receptor and inhibition of adenylyl cyclase in RIN 5AH rat insulinoma cells.
Academic Article A patient with type B insulin resistance syndrome, responsive to immune therapy.
Academic Article Setting sail for glucose homeostasis with the AKAP150-PP2B-anchor.
Concept Immunohistochemistry
Concept Insulin-Like Growth Factor Binding Protein 1
Concept 5' Untranslated Regions
Concept Structure-Activity Relationship
Concept Young Adult
Concept Flavonoids
Concept Receptors, IgE
Concept von Willebrand Factor
Concept Cell Lineage
Concept Second Messenger Systems
Concept Estrus
Concept Caloric Restriction
Concept Mitogen-Activated Protein Kinase 3
Concept Mice
Concept Substrate Specificity
Concept CD4 Lymphocyte Count
Concept Transcription, Genetic
Concept Fasting
Concept Oxidative Phosphorylation
Concept Class Ia Phosphatidylinositol 3-Kinase
Concept Animals, Genetically Modified
Concept Molecular Mimicry
Concept New Zealand
Concept Benzamides
Concept Proteomics
Concept Creatinine
Concept Ritonavir
Concept Tamoxifen
Concept Rats, Wistar
Concept Base Sequence
Concept Chemokines
Concept Mice, Inbred DBA
Concept Oligonucleotide Array Sequence Analysis
Concept Osteocalcin
Concept Regeneration
Concept Electrophoresis, Gel, Two-Dimensional
Concept Pyrrolidonecarboxylic Acid
Concept Calcium Channels
Concept Longevity
Concept Biopsy
Concept Immunoglobulins
Concept HEK293 Cells
Concept Hemophilia A
Concept Chromatography, Liquid
Concept Adipose Tissue, Brown
Concept Up-Regulation
Concept Caspase 3
Concept Obesity
Concept Immunoprecipitation
Concept Protein Denaturation
Concept Autocrine Communication
Concept Animal Feed
Concept Insulin-Like Growth Factor II
Concept Oligonucleotides, Antisense
Concept Core Binding Factor Alpha 1 Subunit
Concept Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
Concept Binding Sites
Concept Antigens, CD34
Concept Calcium Channels, L-Type
Concept Nuclear Localization Signals
Concept Carboxylesterase
Concept Antibodies, Neutralizing
Concept Cricetinae
Concept Adipogenesis
Concept Mice, Inbred NOD
Concept Receptors, Glucagon
Concept Protein Multimerization
Concept Factor X
Concept Norepinephrine
Concept Immunoglobulin E
Concept Analysis of Variance
Concept Smad3 Protein
Concept Enzyme Stability
Concept Feeding Behavior
Concept Atherosclerosis
Concept Interleukin-1beta
Concept Hemostasis
Concept Adenine
Concept Oxidation-Reduction
Concept Protein Stability
Concept G1 Phase
Concept Attitude to Health
Concept Antiviral Agents
Concept Factor VIII
Concept Calcium
Concept Calorimetry
Concept Heterogeneous-Nuclear Ribonucleoproteins
Concept Anemia, Megaloblastic
Concept Intracellular Membranes
Concept Coronary Vessels
Concept Precipitin Tests
Concept Cyclic AMP-Dependent Protein Kinases
Concept STAT3 Transcription Factor
Concept Carcinoembryonic Antigen
Concept TRPV Cation Channels
Concept Sarcoplasmic Reticulum Calcium-Transporting ATPases
Concept Blotting, Western
Concept Mice, Nude
Concept Mice, SCID
Concept Administration, Oral
Concept Glucosephosphate Dehydrogenase
Concept Lysosomes
Concept Arginine
Concept China
Concept Menopause
Concept Amino Acids
Concept Combined Modality Therapy
Concept Endoplasmic Reticulum
Concept Amino Acid Substitution
Concept Binding, Competitive
Concept Blotting, Northern
Concept Hypothalamus
Concept Thiazolidinediones
Concept Mitogen-Activated Protein Kinase 1
Concept Sterol Regulatory Element Binding Protein 1
Concept Aged
Concept 1-Methyl-3-isobutylxanthine
Concept Factor X Deficiency
Concept STAT5 Transcription Factor
Concept Protein Biosynthesis
Concept Amino Acid Sequence
Concept Insulin-Like Growth Factor I
Concept Lipase
Concept GTP-Binding Protein alpha Subunit, Gi2
Concept Methylation
Concept Receptors, G-Protein-Coupled
Concept Mice, Knockout
Concept Harmine
Concept Calcium Signaling
Concept Obesity, Morbid
Concept Extracellular Signal-Regulated MAP Kinases
Concept Proliferating Cell Nuclear Antigen
Concept Cell Size
Concept Fluorescence Resonance Energy Transfer
Concept Insulinoma
Concept CD4-Positive T-Lymphocytes
Concept Polypyrimidine Tract-Binding Protein
Concept Prospective Studies
Concept Leptin
Concept 3' Untranslated Regions
Concept Cross-Sectional Studies
Concept Rats
Concept Calcium-Transporting ATPases
Concept Sterol Esterase
Concept Diabetes Mellitus, Type 1
Concept Succinate Dehydrogenase
Concept Thermogenesis
Concept Protein Tyrosine Phosphatase, Non-Receptor Type 1
Concept Imidazoline Receptors
Concept Serum
Concept Kinetics
Concept Australia
Concept Blood Coagulation
Concept Cyclic AMP Response Element-Binding Protein
Concept Autoantibodies
Concept Adamantane
Concept MafG Transcription Factor
Concept Mechanotransduction, Cellular
Concept Body Mass Index
Concept Tandem Mass Spectrometry
Concept Diagnosis, Differential
Concept Vascular Endothelial Growth Factor A
Concept A Kinase Anchor Proteins
Concept Enzyme-Linked Immunosorbent Assay
Concept Basic Helix-Loop-Helix Transcription Factors
Concept Protein Binding
Concept Intestinal Mucosa
Concept Apoptosis
Concept Tumor Burden
Concept Ki-67 Antigen
Concept Calcium Channel Blockers
Concept Protein Transport
Concept Hepatocyte Nuclear Factor 4
Concept Thinness
Concept Body Temperature Regulation
Concept Databases, Factual
Concept Thiazoles
Concept Chromans
Concept Protein Folding
Concept RNA, Small Interfering
Concept Cyclin D1
Concept CCAAT-Enhancer-Binding Protein-alpha
Concept Diabetes Mellitus, Lipoatrophic
Concept Mass Spectrometry
Concept Protein Processing, Post-Translational
Concept Cell Line, Tumor
Concept Hypoxia-Inducible Factor 1, alpha Subunit
Concept Pancreatic Cyst
Concept RNA-Binding Proteins
Concept Cyclin D2
Concept Centromere
Concept Chromatography, High Pressure Liquid
Concept Spectroscopy, Near-Infrared
Concept MicroRNAs
Concept Zebrafish
Concept Cyclic AMP
Concept Cyclin A
Concept Anti-HIV Agents
Concept Exons
Concept Diabetes Mellitus, Type 2
Concept Basal Metabolism
Concept Glucose Transporter Type 2
Concept Pancrelipase
Concept bcl-Associated Death Protein
Concept Carboxypeptidase H
Concept Mice, Inbred C57BL
Concept Lysine
Concept Sumoylation
Concept Proto-Oncogene Proteins c-akt
Concept Hepatocyte Nuclear Factor 1-beta
Concept Enzyme Activation
Concept Cyclin-Dependent Kinase Inhibitor p16
Concept Insulin-Secreting Cells
Concept RNA Stability
Concept Caspase 7
Concept Alanine Transaminase
Concept Neovascularization, Physiologic
Concept Adiposity
Concept Mice, Mutant Strains
Concept Body Composition
Concept Hepatitis C, Chronic
Concept Adaptation, Physiological
Concept Molecular Structure
Concept Plasmapheresis
Concept Tumor Necrosis Factor-alpha
Concept Middle Aged
Concept Aquaporins
Concept Glycolysis
Concept Cyclin-Dependent Kinase Inhibitor p27
Concept Immunoglobulin Fc Fragments
Concept South Africa
Concept Swine
Concept Retinol-Binding Proteins, Cellular
Concept Chromatography, Affinity
Concept United States
Concept Aging
Concept Janus Kinase 2
Concept Promoter Regions, Genetic
Concept Weight Gain
Concept Rats, Zucker
Concept Thiamine
Concept Bone Marrow Cells
Concept Cysteine
Concept Cyclin-Dependent Kinase 4
Concept Vascular Endothelial Growth Factors
Concept Delayed Diagnosis
Concept Receptors, Adrenergic, beta-3
Concept MAP Kinase Signaling System
Concept Humans
Concept Gluconeogenesis
Concept Down-Regulation
Concept Wakefulness
Concept Organ Size
Concept Melanins
Concept Intracranial Hemorrhages
Concept Chromatography, Ion Exchange
Concept Hematopoietic Stem Cells
Concept Plasma
Concept Pulsatile Flow
Concept Rabbits
Concept Membrane Transport Proteins
Concept Lipolysis
Concept Epigenomics
Concept Potassium Chloride
Concept Hepatocyte Nuclear Factor 1-alpha
Concept Reticulocytes
Concept Adaptor Proteins, Signal Transducing
Concept Glucose Transporter Type 4
Concept Glucose Tolerance Test
Concept Glucose Clamp Technique
Concept Macaca mulatta
Concept Lymphocytes
Concept Longitudinal Studies
Concept Active Transport, Cell Nucleus
Concept Androstadienes
Concept Mitochondria
Concept Brain
Concept Flow Cytometry
Concept Aged, 80 and over
Concept Protein Conformation
Concept Serine
Concept Duodenum
Concept Activating Transcription Factor 4
Concept Mice, Transgenic
Concept T-Lymphocytes
Concept Cyclin D
Concept Estrogen Receptor alpha
Concept Antigens, CD
Concept Phosphorylation
Concept North America
Concept Transforming Growth Factor beta1
Concept Signal Transduction
Concept Multivariate Analysis
Concept Oxygen
Concept Adipose Tissue, White
Concept Apolipoproteins E
Concept Epithelial-Mesenchymal Transition
Concept HeLa Cells
Concept Drug Discovery
Concept Insulin Receptor Substrate Proteins
Concept Cell Nucleus
Concept S Phase
Concept Ion Channels
Concept Cell Division
Concept Adipose Tissue
Concept Drug Design
Concept Age of Onset
Concept Canada
Concept Receptors, Neuropeptide Y
Concept Isoproterenol
Concept Mice, Inbred BALB C
Concept Imidazoles
Concept Pyrazoles
Concept Telomere
Concept Catalysis
Concept Body Weight
Concept Receptor, Cannabinoid, CB1
Concept CD8-Positive T-Lymphocytes
Concept Calgranulin A
Concept Mice, Obese
Concept Deamino Arginine Vasopressin
Concept Phosphoenolpyruvate Carboxykinase (ATP)
Concept Receptor, IGF Type 1
Concept Telomerase
Concept Aryl Hydrocarbon Receptor Nuclear Translocator
Academic Article Tribbles 3 mediates endoplasmic reticulum stress-induced insulin resistance in skeletal muscle.
Academic Article Thermic effect of a meal. 3. Effect of dietary supplementation in chronically undernourished human subjects.
Academic Article Imidazolines stimulate release of insulin from RIN-5AH cells independently from I1- and I2-imidazoline receptors.
Academic Article Identifying biomarkers of subclinical diabetes.
Academic Article Growth factor signalling in the regulation of a-cell fate.
Academic Article Human ß-cell proliferation and intracellular signaling: driving in the dark without a road map.
Academic Article Metabolic responses to repeated infusions of identical doses of norepinephrine in chronically energy deficient human subjects.
Academic Article Cannabinoids inhibit insulin receptor signaling in pancreatic ß-cells.
Academic Article Glucose activates free fatty acid receptor 1 gene transcription via phosphatidylinositol-3-kinase-dependent O-GlcNAcylation of pancreas-duodenum homeobox-1.
Academic Article Class IA phosphatidylinositol 3-kinase in pancreatic ß cells controls insulin secretion by multiple mechanisms.
Academic Article GIP: no longer the neglected incretin twin?
Academic Article Effect of IL28B genotype on early viral kinetics during interferon-free treatment of patients with chronic hepatitis C.
Academic Article Loss of glucagon-like peptide-2-induced proliferation following intestinal epithelial insulin-like growth factor-1-receptor deletion.
Academic Article Soluble factors secreted by T cells promote ß-cell proliferation.
Academic Article New opportunities: harnessing induced pluripotency for discovery in diabetes and metabolism.
Academic Article p85a deficiency protects ß-cells from endoplasmic reticulum stress-induced apoptosis.
Academic Article Insulin resistance alters islet morphology in nondiabetic humans.
Academic Article Perceptions about quality of life in a school-based population of adolescents with menorrhagia: implications for adolescents with bleeding disorders.
Academic Article Efficacy and safety of danoprevir-ritonavir plus peginterferon alfa-2a-ribavirin in hepatitis C virus genotype 1 prior null responders.
Academic Article The regulation of pre- and post-maturational plasticity of mammalian islet cell mass.
Academic Article Insulin regulates carboxypeptidase E by modulating translation initiation scaffolding protein eIF4G1 in pancreatic ß cells.
Academic Article Disruption of protein-tyrosine phosphatase 1B expression in the pancreas affects ß-cell function.
Academic Article Comparable generation of activin-induced definitive endoderm via additive Wnt or BMP signaling in absence of serum.
Academic Article Palmitate induces mRNA translation and increases ER protein load in islet ß-cells via activation of the mammalian target of rapamycin pathway.
Academic Article Recombinant factor VIII Fc fusion protein: extended-interval dosing maintains low bleeding rates and correlates with von Willebrand factor levels.
Academic Article Summary of the Keystone islet workshop (April 2014): the increasing demand for human islet availability in diabetes research.
Academic Article Maternal insulin resistance and transient hyperglycemia impact the metabolic and endocrine phenotypes of offspring.
Academic Article Pancreatic T cell protein-tyrosine phosphatase deficiency affects beta cell function in mice.
Academic Article High-level Gpr56 expression is dispensable for the maintenance and function of hematopoietic stem and progenitor cells in mice.
Academic Article The effect of mild to moderate renal impairment on the pharmacokinetics of the nucleoside analog hepatitis C virus polymerase inhibitor mericitabine.
Academic Article Human ß-cell proliferation and intracellular signaling: part 3.
Academic Article Epigenetic modifiers of islet function and mass.
Academic Article Recombinant factor VIII Fc fusion protein for the prevention and treatment of bleeding in children with severe hemophilia A.
Academic Article Excessive Cellular Proliferation Negatively Impacts Reprogramming Efficiency of Human Fibroblasts.
Academic Article Compensatory Islet Response to Insulin Resistance Revealed by Quantitative Proteomics.
Academic Article Deficiency of Fc?R1 Increases Body Weight Gain but Improves Glucose Tolerance in Diet-Induced Obese Mice.
Academic Article Clinical-Economic Modeling Analysis Of Human Papillomavirus (Hpv) Co-Testing With Genotyping Versus Primary Hpv Testing For Cervical Cancer Screening.
Academic Article Harnessing immune cells to enhance ß-cell mass in type 1 diabetes.
Academic Article SerpinB1 Promotes Pancreatic ß Cell Proliferation.
Academic Article Early Developmental Perturbations in a Human Stem Cell Model of MODY5/HNF1B Pancreatic Hypoplasia.
Academic Article Fibroblast Growth Factor 21 (FGF21) Protects against High Fat Diet Induced Inflammation and Islet Hyperplasia in Pancreas.
Academic Article ß-Cell Glucose Sensitivity Is Linked to Insulin/Glucagon Bihormonal Cells in Nondiabetic Humans.
Academic Article Proinflammatory Cytokines Induce Endocrine Differentiation in Pancreatic Ductal Cells via STAT3-Dependent NGN3 Activation.
Academic Article ERR?-A New Player in ß Cell Maturation.
Academic Article Inhibition of TGF-ß Signaling Promotes Human Pancreatic ß-Cell Replication.
Academic Article The Hypoglycemic Phenotype Is Islet Cell-Autonomous in Short-Chain Hydroxyacyl-CoA Dehydrogenase-Deficient Mice.
Academic Article Inhibition of DYRK1A Stimulates Human ß-Cell Proliferation.
Academic Article Is Transforming Stem Cells to Pancreatic Beta Cells Still the Holy Grail for Type 2 Diabetes?
Academic Article Differential Roles of Insulin and IGF-1 Receptors in Adipose Tissue Development and Function.
Grant Leptin modulation of insulin action in the islet b-cell
Grant Role of IGF-1 and insulin receptors beta-cell survival
Grant Role of Leptin in Islet Growth
Grant Dissecting the Death Pathway in Islet Beta Cells
Grant Role of IGF-1 and insulin receptors beta-cell survival
Academic Article Novel factors modulating human ß-cell proliferation.
Academic Article Corrigendum: IRS1 deficiency protects ß-cells against ER stress-induced apoptosis by modulating sXBP-1 stability and protein translation.
Academic Article Adult, previously untreated patients remain a significant therapeutic challenge.
Academic Article Adipocyte Dynamics and Reversible Metabolic Syndrome in Mice with an Inducible Adipocyte-Specific Deletion of the Insulin Receptor.
Academic Article GLP-1 signalling compensates for impaired insulin signalling in regulating beta cell proliferation in ßIRKO mice.
Academic Article Community based kangaroo mother care for low birth weight babies: A pilot study.
Academic Article Age-dependent insulin resistance in male mice with null deletion of the carcinoembryonic antigen-related cell adhesion molecule 2 gene.
Academic Article Nuclear import of glucokinase in pancreatic beta-cells is mediated by a nuclear localization signal and modulated by SUMOylation.
Academic Article Isoform-selective inhibitor of histone deacetylase 3 (HDAC3) limits pancreatic islet infiltration and protects female nonobese diabetic mice from diabetes.
Academic Article Significance of CD34 Negative Hematopoietic Stem Cells and CD34 Positive Mesenchymal Stem Cells - A Valuable Dimension to the Current Understanding.
Academic Article The role of the carboxyl ester lipase (CEL) gene in pancreatic disease.
Academic Article Signaling between pancreatic ß cells and macrophages via S100 calcium-binding protein A8 exacerbates ß-cell apoptosis and islet inflammation.
Academic Article Sex differences underlying pancreatic islet biology and its dysfunction.
Academic Article Reduced expression of the RNA-binding protein HuD in pancreatic neuroendocrine tumors correlates with low p27Kip1 levels and poor prognosis.
Academic Article Glucose Controls the Expression of Polypyrimidine Tract-Binding Protein 1 via the Insulin Receptor Signaling Pathway in Pancreatic ß Cells.
Academic Article Fluorescent probes for G-protein-coupled receptor drug discovery.
Academic Article Insulin receptor-mediated signaling regulates pluripotency markers and lineage differentiation.
Academic Article Attenuation of PKCd enhances metabolic activity and promotes expansion of blood progenitors.
Academic Article Forkhead box protein O1 (FoxO1) regulates hepatic serine protease inhibitor B1 (serpinB1) expression in a non-cell-autonomous fashion.
Grant Regulation of Autoimmune Type 1 Diabetes by Serpins B1 and A1 (Alpha 1-Antitrypsin)
Academic Article Loss-of-Function Mutation in Thiamine Transporter 1 in a Family With Autosomal Dominant Diabetes.
Academic Article Boosting to Amplify Signal with Isobaric Labeling (BASIL) Strategy for Comprehensive Quantitative Phosphoproteomic Characterization of Small Populations of Cells.
Academic Article Human duct cells contribute to ß cell compensation in insulin resistance.
Academic Article ß-Cell Fate in Human Insulin Resistance and Type 2 Diabetes: A Perspective on Islet Plasticity.
Academic Article HNF4A Haploinsufficiency in MODY1 Abrogates Liver and Pancreas Differentiation from Patient-Derived Induced Pluripotent Stem Cells.
Academic Article How, When, and Where Do Human ß-Cells Regenerate?
Grant Pathways and critical regulators of early beta-cell dysfunction in type 1 diabetes
Academic Article RADAR: differential analysis of MeRIP-seq data with a random effect model.
Academic Article Efficacy, safety and pharmacokinetics of a new high-purity factor X concentrate in women and girls with hereditary factor X deficiency.
Academic Article Luseogliflozin increases beta cell proliferation through humoral factors that activate an insulin receptor- and IGF-1 receptor-independent pathway.
Academic Article Sites of initial bleeding episodes, mode of delivery and age of diagnosis in babies with haemophilia diagnosed before the age of 2 years: a report from The Centers for Disease Control and Prevention's (CDC) Universal Data Collection (UDC) project.
Academic Article Switching from twice-daily raltegravir plus tenofovir disoproxil fumarate/emtricitabine to once-daily elvitegravir/cobicistat/emtricitabine/tenofovir disoproxil fumarate in virologically suppressed, HIV-1-infected subjects: 48 weeks data.
Academic Article A MAFG-lncRNA axis links systemic nutrient abundance to hepatic glucose metabolism.
Academic Article Native Zinc Catalyzes Selective and Traceless Release of Small Molecules in ß-Cells.
Academic Article Parental metabolic syndrome epigenetically reprograms offspring hepatic lipid metabolism in mice.
Academic Article The longitudinal effect of body adiposity on joint mobility in young males with Haemophilia A.
Grant Role of 12-lipoxygenase and 12-HETE signaling in beta-cell dysfunction
Academic Article More is better: combinatorial therapy to restore ß-cell function in diabetes.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.