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One or more keywords matched the following items that are connected to Franks, Paul
Item TypeName
Academic Article Type 2 diabetes-associated missense polymorphisms KCNJ11 E23K and ABCC8 A1369S influence progression to diabetes and response to interventions in the Diabetes Prevention Program.
Academic Article Genetic modulation of lipid profiles following lifestyle modification or metformin treatment: the Diabetes Prevention Program.
Academic Article Effects of genetic variants previously associated with fasting glucose and insulin in the Diabetes Prevention Program.
Academic Article Common variants in 40 genes assessed for diabetes incidence and response to metformin and lifestyle intervention in the diabetes prevention program.
Academic Article Genetic predisposition to long-term nondiabetic deteriorations in glucose homeostasis: Ten-year follow-up of the GLACIER study.
Academic Article New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.
Academic Article Common variants in genes encoding adiponectin (ADIPOQ) and its receptors (ADIPOR1/2), adiponectin concentrations, and diabetes incidence in the Diabetes Prevention Program.
Academic Article The Pro12Ala variant at the peroxisome proliferator-activated receptor gamma gene and change in obesity-related traits in the Diabetes Prevention Program.
Academic Article Extension of type 2 diabetes genome-wide association scan results in the diabetes prevention program.
Academic Article A genome-wide association search for type 2 diabetes genes in African Americans.
Academic Article Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.
Academic Article A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.
Academic Article Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes.
Academic Article TCF7L2 polymorphism, weight loss and proinsulin:insulin ratio in the diabetes prevention program.
Academic Article Obesity genotype score and cardiovascular risk in women with type 2 diabetes mellitus.
Academic Article Testing of diabetes-associated WFS1 polymorphisms in the Diabetes Prevention Program.
Academic Article Association between parental history of diabetes and type 2 diabetes genetic risk scores in the PPP-Botnia and Framingham Offspring Studies.
Concept Diabetes Mellitus, Type 1
Concept Diabetes Mellitus, Type 2
Academic Article Gene-environment and gene-treatment interactions in type 2 diabetes: progress, pitfalls, and prospects.
Academic Article Variation at the melanocortin 4 receptor gene and response to weight-loss interventions in the diabetes prevention program.
Academic Article Genetic risk of progression to type 2 diabetes and response to intensive lifestyle or metformin in prediabetic women with and without a history of gestational diabetes mellitus.
Academic Article Clinical and genetic determinants of progression of type 2 diabetes: a DIRECT study.
Academic Article Common variation at PPARGC1A/B and change in body composition and metabolic traits following preventive interventions: the Diabetes Prevention Program.
Academic Article The influence of rare genetic variation in SLC30A8 on diabetes incidence and ß-cell function.
Academic Article Long-term changes in dietary and food intake behaviour in the Diabetes Prevention Program Outcomes Study.
Academic Article Variation in the eNOS gene modifies the association between total energy expenditure and glucose intolerance.
Academic Article Review: exercise training reduces HbA1c levels but not body mass in type 2 diabetes mellitus.
Academic Article Does physical activity energy expenditure explain the between-individual variation in plasma leptin concentrations after adjusting for differences in body composition?
Academic Article Gene-lifestyle interaction on risk of type 2 diabetes.
Academic Article Association analysis of Krüppel-like factor 11 variants with type 2 diabetes in Pima Indians.
Academic Article Replication and extension of genome-wide association study results for obesity in 4923 adults from northern Sweden.
Academic Article Meta-analysis of the Gly482Ser variant in PPARGC1A in type 2 diabetes and related phenotypes.
Academic Article Associations between general and abdominal adiposity and mortality in individuals with diabetes mellitus.
Academic Article Mediterranean diet and type 2 diabetes risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) study: the InterAct project.
Academic Article Candidate gene association study in type 2 diabetes indicates a role for genes involved in beta-cell function as well as insulin action.
Academic Article PGC-1alpha gene and physical activity in type 2 diabetes mellitus.
Academic Article Genetic variation in UCP2 (uncoupling protein-2) is associated with energy metabolism in Pima Indians.
Academic Article Gestational glucose tolerance and risk of type 2 diabetes in young Pima Indian offspring.
Academic Article TCF7L2 polymorphisms modulate proinsulin levels and beta-cell function in a British Europid population.
Academic Article Lamin A/C polymorphisms, type 2 diabetes, and the metabolic syndrome: case-control and quantitative trait studies.
Academic Article Interaction between an 11betaHSD1 gene variant and birth era modifies the risk of hypertension in Pima Indians.
Academic Article Replication of the association between variants in WFS1 and risk of type 2 diabetes in European populations.
Academic Article Detailed investigation of the role of common and low-frequency WFS1 variants in type 2 diabetes risk.
Academic Article Tea consumption and incidence of type 2 diabetes in Europe: the EPIC-InterAct case-cohort study.
Academic Article Invited commentary: Gene X lifestyle interactions and complex disease traits--inferring cause and effect from observational data, sine qua non.
Academic Article Evaluating the discriminative power of multi-trait genetic risk scores for type 2 diabetes in a northern Swedish population.
Academic Article Common genetic variants highlight the role of insulin resistance and body fat distribution in type 2 diabetes, independent of obesity.
Academic Article Lower educational level is a predictor of incident type 2 diabetes in European countries: the EPIC-InterAct study.
Academic Article Smoking and long-term risk of type 2 diabetes: the EPIC-InterAct study in European populations.
Academic Article Alcohol consumption and risk of type 2 diabetes in European men and women: influence of beverage type and body size The EPIC-InterAct study.
Academic Article The impact of lifestyle intervention on sedentary time in individuals at high risk of diabetes.
Academic Article In search of quality evidence for lifestyle management and glycemic control in children and adolescents with type 2 diabetes: A systematic review.
Academic Article Gene × environment interactions in type 2 diabetes.
Academic Article Non-invasive risk scores for prediction of type 2 diabetes (EPIC-InterAct): a validation of existing models.
Academic Article Age at menopause, reproductive life span, and type 2 diabetes risk: results from the EPIC-InterAct study.
Academic Article Physical activity energy expenditure may mediate the relationship between plasma leptin levels and worsening insulin resistance independently of adiposity.
Academic Article Previously associated type 2 diabetes variants may interact with physical activity to modify the risk of impaired glucose regulation and type 2 diabetes: a study of 16,003 Swedish adults.
Academic Article Genomic variants at the PINK1 locus are associated with transcript abundance and plasma nonesterified fatty acid concentrations in European whites.
Academic Article Design and cohort description of the InterAct Project: an examination of the interaction of genetic and lifestyle factors on the incidence of type 2 diabetes in the EPIC Study.
Academic Article Long-term risk of incident type 2 diabetes and measures of overall and regional obesity: the EPIC-InterAct case-cohort study.
Academic Article The link between family history and risk of type 2 diabetes is not explained by anthropometric, lifestyle or genetic risk factors: the EPIC-InterAct study.
Academic Article The association between dietary flavonoid and lignan intakes and incident type 2 diabetes in European populations: the EPIC-InterAct study.
Academic Article Dietary intakes of individual flavanols and flavonols are inversely associated with incident type 2 diabetes in European populations.
Academic Article Consumption of fatty foods and incident type 2 diabetes in populations from eight European countries.
Academic Article Association between dietary meat consumption and incident type 2 diabetes: the EPIC-InterAct study.
Academic Article The prospective association between total and type of fish intake and type 2 diabetes in 8 European countries: EPIC-InterAct Study.
Academic Article Dietary vitamin D intake and risk of type 2 diabetes in the European Prospective Investigation into Cancer and Nutrition: the EPIC-InterAct study.
Academic Article Dietary protein intake and incidence of type 2 diabetes in Europe: the EPIC-InterAct Case-Cohort Study.
Academic Article Telomere length in blood and skeletal muscle in relation to measures of glycaemia and insulinaemia.
Academic Article Consumption of sweet beverages and type 2 diabetes incidence in European adults: results from EPIC-InterAct.
Academic Article Physical activity reduces the risk of incident type 2 diabetes in general and in abdominally lean and obese men and women: the EPIC-InterAct Study.
Academic Article Gene-physical activity interactions and their impact on diabetes.
Academic Article Age at menarche and type 2 diabetes risk: the EPIC-InterAct study.
Academic Article Ethnicity is an independent risk indicator when estimating diabetes risk with FINDRISC scores: a cross sectional study comparing immigrants from the Middle East and native Swedes.
Academic Article Gene-lifestyle interaction and type 2 diabetes: the EPIC interact case-cohort study.
Academic Article Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility.
Academic Article Differences in the prospective association between individual plasma phospholipid saturated fatty acids and incident type 2 diabetes: the EPIC-InterAct case-cohort study.
Academic Article Ethnic differences in the contribution of insulin action and secretion to type 2 diabetes in immigrants from the Middle East compared to native Swedes.
Academic Article The association between dietary energy density and type 2 diabetes in Europe: results from the EPIC-InterAct Study.
Academic Article Expression of phosphofructokinase in skeletal muscle is influenced by genetic variation and associated with insulin sensitivity.
Academic Article The amount and type of dairy product intake and incident type 2 diabetes: results from the EPIC-InterAct Study.
Academic Article First-degree relatives of type 2 diabetic patients have reduced expression of genes involved in fatty acid metabolism in skeletal muscle.
Academic Article Fruit and vegetable intake and type 2 diabetes: EPIC-InterAct prospective study and meta-analysis.
Academic Article Genetic risk scores ascertained in early adulthood and the prediction of type 2 diabetes later in life.
Academic Article Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: rationale and design of the epidemiological studies within the IMI DIRECT Consortium.
Academic Article A family history of diabetes determines poorer glycaemic control and younger age of diabetes onset in immigrants from the Middle East compared with native Swedes.
Academic Article Exercise and diabetes-related cardiovascular disease: systematic review of published evidence from observational studies and clinical trials.
Academic Article A Mendelian Randomization Study of Circulating Uric Acid and Type 2 Diabetes.
Academic Article Association of subclinical inflammation with deterioration of glycaemia before the diagnosis of type 2 diabetes: the KORA S4/F4 study.
Academic Article Country of birth modifies the association of fatty liver index with insulin action in Middle Eastern immigrants to Sweden.
Academic Article Genetic Predisposition to Weight Loss and Regain With Lifestyle Intervention: Analyses From the Diabetes Prevention Program and the Look AHEAD Randomized Controlled Trials.
Academic Article Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci.
Academic Article Lifestyle and Metformin Ameliorate Insulin Sensitivity Independently of the Genetic Burden of Established Insulin Resistance Variants in Diabetes Prevention Program Participants.
Academic Article Innate biology versus lifestyle behaviour in the aetiology of obesity and type 2 diabetes: the GLACIER Study.
Academic Article Putting the Genome in Context: Gene-Environment Interactions in Type 2 Diabetes.
Academic Article Association of Multiple Biomarkers of Iron Metabolism and Type 2 Diabetes: The EPIC-InterAct Study.
Academic Article A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease.
Academic Article Association of Plasma Phospholipid n-3 and n-6 Polyunsaturated Fatty Acids with Type 2 Diabetes: The EPIC-InterAct Case-Cohort Study.
Academic Article The genetic architecture of type 2 diabetes.
Academic Article Association Between Low-Density Lipoprotein Cholesterol-Lowering Genetic Variants and Risk of Type 2 Diabetes: A Meta-analysis.
Academic Article Higher Prevalence of Type 2 Diabetes in Men Than in Women Is Associated With Differences in Visceral Fat Mass.
Academic Article Exposing the exposures responsible for type 2 diabetes and obesity.
Academic Article Sustained influence of metformin therapy on circulating glucagon-like peptide-1 levels in individuals with and without type 2 diabetes.
Academic Article Plasma Levels of Fatty Acid-Binding Protein 4, Retinol-Binding Protein 4, High-Molecular-Weight Adiponectin, and Cardiovascular Mortality Among Men With Type 2 Diabetes: A 22-Year Prospective Study.
Academic Article Bicycling to Work and Primordial Prevention of Cardiovascular Risk: A Cohort Study Among Swedish Men and Women.
Academic Article Activity and Sedentary Time 10 Years After a Successful Lifestyle Intervention: The Diabetes Prevention Program.
Academic Article Statistical power considerations in genotype-based recall randomized controlled trials.
Academic Article Lifestyle and precision diabetes medicine: will genomics help optimise the prediction, prevention and treatment of type 2 diabetes through lifestyle therapy?
Academic Article Predicting glycated hemoglobin levels in the non-diabetic general population: Development and validation of the DIRECT-DETECT prediction model - a DIRECT study.
Academic Article A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk.
Academic Article An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans.
Academic Article Variation in Maturity-Onset Diabetes of the Young Genes Influence Response to Interventions for Diabetes Prevention.
Academic Article Evidence-based prioritisation and enrichment of genes interacting with metformin in type 2 diabetes.
Academic Article Lifestyle precision medicine: the next generation in type 2 diabetes prevention?
Academic Article A combination of plasma phospholipid fatty acids and its association with incidence of type 2 diabetes: The EPIC-InterAct case-cohort study.
Academic Article Precision Medicine in Obesity and Type 2 Diabetes: The Relevance of Early-Life Exposures.
Academic Article Exome-wide association study of plasma lipids in >300,000 individuals.
Academic Article Interaction of Dietary and Genetic Factors Influencing Body Iron Status and Risk of Type 2 Diabetes Within the EPIC-InterAct Study.
Academic Article Rates of glycaemic deterioration in a real-world population with type 2 diabetes.
Academic Article Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.
Academic Article Family history of diabetes and its relationship with insulin secretion and insulin sensitivity in Iraqi immigrants and native Swedes: a population-based cohort study.
Academic Article Aberrant intestinal microbiota in individuals with prediabetes.
Academic Article Gene-lifestyle interplay in type 2 diabetes.
Academic Article Circulating Fetuin-A and Risk of Type 2 Diabetes: A Mendelian Randomization Analysis.
Academic Article Association of changes in inflammation with variation in glycaemia, insulin resistance and secretion based on the KORA study.
Academic Article Midlife development of type 2 diabetes and hypertension in women by history of hypertensive disorders of pregnancy.
Academic Article A Global Overview of Precision Medicine in Type 2 Diabetes.
Academic Article Genome-Wide and Abdominal MRI Data Provide Evidence That a Genetically Determined Favorable Adiposity Phenotype Is Characterized by Lower Ectopic Liver Fat and Lower Risk of Type 2 Diabetes, Heart Disease, and Hypertension.
Academic Article Postpregnancy BMI in the Progression From Hypertensive Disorders of Pregnancy to Type 2 Diabetes.
Academic Article Association of Plasma Vitamin D Metabolites With Incident Type 2 Diabetes: EPIC-InterAct Case-Cohort Study.
Academic Article Dairy Product Intake and Risk of Type 2 Diabetes in EPIC-InterAct: A Mendelian Randomization Study.
Academic Article Variation in the Plasma Membrane Monoamine Transporter (PMAT) (Encoded by SLC29A4) and Organic Cation Transporter 1 (OCT1) (Encoded by SLC22A1) and Gastrointestinal Intolerance to Metformin in Type 2 Diabetes: An IMI DIRECT Study.
Academic Article Long-Term Weight Loss With Metformin or Lifestyle Intervention in the Diabetes Prevention Program Outcomes Study.
Academic Article Generalizability of a Diabetes-Associated Country-Specific Exploratory Dietary Pattern Is Feasible Across European Populations.
Academic Article Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: descriptive characteristics of the epidemiological studies within the IMI DIRECT Consortium.
Academic Article Quality of dietary fat and genetic risk of type 2 diabetes: individual participant data meta-analysis.
Academic Article Estimated Substitution of Tea or Coffee for Sugar-Sweetened Beverages Was Associated with Lower Type 2 Diabetes Incidence in Case-Cohort Analysis across 8 European Countries in the EPIC-InterAct Study.
Academic Article Interaction Between Type 2 Diabetes Prevention Strategies and Genetic Determinants of Coronary Artery Disease on Cardiometabolic Risk Factors.
Academic Article The role of physical activity in metabolic homeostasis before and after the onset of type 2 diabetes: an IMI DIRECT study.
Academic Article Association of plasma biomarkers of fruit and vegetable intake with incident type 2 diabetes: EPIC-InterAct case-cohort study in eight European countries.
Academic Article Dietary metabolite profiling brings new insight into the relationship between nutrition and metabolic risk: An IMI DIRECT study.
Academic Article Replacement of Red and Processed Meat With Other Food Sources of Protein and the Risk of Type 2 Diabetes in European Populations: The EPIC-InterAct Study.
Academic Article An investigation of causal relationships between prediabetes and vascular complications.
Academic Article The association between circulating 25-hydroxyvitamin D metabolites and type 2 diabetes in European populations: A meta-analysis and Mendelian randomisation analysis.
Academic Article Genome-wide association analysis of type 2 diabetes in the EPIC-InterAct study.
Academic Article Post-load glucose subgroups and associated metabolic traits in individuals with type 2 diabetes: An IMI-DIRECT study.
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  • Diabetes Mellitus Type 2
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.