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One or more keywords matched the following properties of Ogino, Shuji
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overview Dr. Ogino is Chief, Program in MPE Molecular Pathological Epidemiology of Department of Pathology, Brigham and Women's Hospital, developing the integrative interdisciplinary science of "Molecular Pathological Epidemiology (MPE)". He is an associate member of Broad Institute of MIT and Harvard. He has been serving as Chairperson for The International MPE Meeting Series since 2013. The 4th International Molecular Pathological Epidemiology (MPE) Meeting is planned to be held on May 31 to June 1, 2018 in Boston, MA, USA. Dr. Ogino's research has a broad theme: Integration of Molecular Pathology, Omics (Genomics), ?Epidemiology, Bioinformatics, and Population Health Science. Dr. Ogino's focus is to develop new scientific disciplines, and develop new data analysis framework and methodologies. The Ogino Lab uses gastrointestinal cancers as model human diseases (including colorectal carcinoma, colorectal polyp, colorectal adenoma, pancreatic adenocarcinoma, neuroendocrine tumor, pancreatic endocrine tumor, carcinoid tumour). We have been analyzing germline and somatic genomics, transcriptomics, epigenomics, and immunomics in human tumors. Using massively parallel sequencing (next generation sequencing) technologies, the Ogino Lab has sequenced whole exome of over 1,000 colorectal carcinomas with high dimensional annotations, and calculated tumor neoantigen load. In addition, the Ogino Lab has obtained data on transcriptome of over 250 colorectal carcinomas (by RNA sequencing). Dr. Ogino has created a number of new research frameworks, concepts, paradigms, and models, including molecular pathological epidemiology (MPE), the GWAS-MPE approach, the colorectal continuum model, the etiologic field effect model, the causal inference-MPE integration, lifecourse-MPE approach, social MPE, immuno-MPE (immunology-MPE integration), pharmaco-MPE, microbiology-MPE integration, MPE-comparative effectiveness research integration, and nutritional MPE.
overview Dr. Ogino's research has a broad theme: Integration of Molecular Pathology, Omics (Genomics), Epidemiology, Bioinformatics, and Population Health Science. Dr. Ogino's focus is to develop new scientific disciplines, and develop new data analysis framework and methodologies. The Ogino Lab uses gastrointestinal cancers as model human diseases (including colorectal carcinoma, colorectal polyp, colorectal adenoma, pancreatic adenocarcinoma, neuroendocrine tumor, pancreatic endocrine tumor, carcinoid tumour). We have been analyzing germline and somatic genomics, transcriptomics, epigenomics, and immunomics in human tumors. Using massively parallel sequencing (next generation sequencing) technologies, the Ogino Lab has sequenced whole exome of over 1,000 colorectal carcinomas with high dimensional annotations, and calculated tumor neoantigen load. In addition, the Ogino Lab has obtained data on transcriptome of over 250 colorectal carcinomas (by RNA sequencing).
One or more keywords matched the following items that are connected to Ogino, Shuji
Item TypeName
Academic Article Epigenetic profiling of synchronous colorectal neoplasias by quantitative DNA methylation analysis.
Academic Article A prospective cohort study shows unique epigenetic, genetic, and prognostic features of synchronous colorectal cancers.
Academic Article PIK3CA mutation in colorectal cancer: relationship with genetic and epigenetic alterations.
Academic Article Epigenomic diversity of colorectal cancer indicated by LINE-1 methylation in a database of 869 tumors.
Academic Article A human, double-blind, placebo-controlled, crossover trial of prebiotic, probiotic, and synbiotic supplementation: effects on luminal, inflammatory, epigenetic, and epithelial biomarkers of colorectal cancer.
Academic Article Molecular pathological epidemiology of epigenetics: emerging integrative science to analyze environment, host, and disease.
Concept Epigenomics
Academic Article A prospective study of duration of smoking cessation and colorectal cancer risk by epigenetics-related tumor classification.
Academic Article Molecular pathological epidemiology gives clues to paradoxical findings.
Academic Article Integration of molecular pathology, epidemiology and social science for global precision medicine.
Academic Article Review Article: The Role of Molecular Pathological Epidemiology in the Study of Neoplastic and Non-neoplastic Diseases in the Era of Precision Medicine.
Grant Epigenetic Events and Colorectal Cancer Epidemiology
Grant Molecular Epidemiology of Colorectal Cancer
Academic Article Genetic Variants in Epigenetic Pathways and Risks of Multiple Cancers in the GAME-ON Consortium.
Academic Article Body mass index and risk of colorectal carcinoma subtypes classified by tumor differentiation status.
Academic Article Integrative Genome-Scale DNA Methylation Analysis of a Large and Unselected Cohort Reveals 5 Distinct Subtypes of Colorectal Adenocarcinomas.
Search Criteria
  • Epigenomics
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.