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One or more keywords matched the following properties of Ogino, Shuji
PropertyValue
keywords Epidemiology, Molecular
keywords Molecular Pathological Epidemiology
keywords Nutritional Epidemiology
keywords Immuno-MPE (Molecular Pathological Epidemiology)
keywords Pharmaco-MPE (Molecular Pathological Epidemiology)
keywords Nutritional MPE (Molecular Pathological Epidemiology)
keywords Molecular Pathologic Epidemiology
keywords Causal Inference-MPE (Molecular Pathological Epidemiology)
overview Dr. Ogino is Chief, Program in MPE Molecular Pathological Epidemiology of Department of Pathology, Brigham and Women's Hospital, developing the integrative interdisciplinary science of "Molecular Pathological Epidemiology (MPE)". He is an associate member of Broad Institute of MIT and Harvard. He has been serving as Chairperson for The International MPE Meeting Series since 2013. The 4th International Molecular Pathological Epidemiology (MPE) Meeting is planned to be held on May 31 to June 1, 2018 in Boston, MA, USA. Dr. Ogino's research has a broad theme: Integration of Molecular Pathology, Omics (Genomics), ?Epidemiology, Bioinformatics, and Population Health Science. Dr. Ogino's focus is to develop new scientific disciplines, and develop new data analysis framework and methodologies. The Ogino Lab uses gastrointestinal cancers as model human diseases (including colorectal carcinoma, colorectal polyp, colorectal adenoma, pancreatic adenocarcinoma, neuroendocrine tumor, pancreatic endocrine tumor, carcinoid tumour). We have been analyzing germline and somatic genomics, transcriptomics, epigenomics, and immunomics in human tumors. Using massively parallel sequencing (next generation sequencing) technologies, the Ogino Lab has sequenced whole exome of over 1,000 colorectal carcinomas with high dimensional annotations, and calculated tumor neoantigen load. In addition, the Ogino Lab has obtained data on transcriptome of over 250 colorectal carcinomas (by RNA sequencing). Dr. Ogino has created a number of new research frameworks, concepts, paradigms, and models, including molecular pathological epidemiology (MPE), the GWAS-MPE approach, the colorectal continuum model, the etiologic field effect model, the causal inference-MPE integration, lifecourse-MPE approach, social MPE, immuno-MPE (immunology-MPE integration), pharmaco-MPE, microbiology-MPE integration, MPE-comparative effectiveness research integration, and nutritional MPE.
overview Dr. Ogino is Chief, Program in MPE Molecular Pathological Epidemiology of Department of Pathology, Brigham and Women's Hospital, developing the integrative interdisciplinary science of "Molecular Pathological Epidemiology (MPE)". He is an associate member of Broad Institute of MIT and Harvard. He has been serving as the Chair or Co-Chair for The International MPE Meeting Series since 2013. The 5th International Molecular Pathological Epidemiology (MPE) Meeting is planned to be held virtually on May 24 to 25, 2021.
overview Dr. Ogino's research has a broad theme: Integration of Molecular Pathology, Omics (Genomics), Epidemiology, Bioinformatics, and Population Health Science. Dr. Ogino's focus is to develop new scientific disciplines, and develop new data analysis framework and methodologies. The Ogino Lab uses gastrointestinal cancers as model human diseases (including colorectal carcinoma, colorectal polyp, colorectal adenoma, pancreatic adenocarcinoma, neuroendocrine tumor, pancreatic endocrine tumor, carcinoid tumour). We have been analyzing germline and somatic genomics, transcriptomics, epigenomics, and immunomics in human tumors. Using massively parallel sequencing (next generation sequencing) technologies, the Ogino Lab has sequenced whole exome of over 1,000 colorectal carcinomas with high dimensional annotations, and calculated tumor neoantigen load. In addition, the Ogino Lab has obtained data on transcriptome of over 600 colorectal carcinomas (by RNA sequencing).
overview Dr. Ogino has created a number of new research frameworks, concepts, paradigms, and models, including molecular pathological epidemiology (MPE) (Ogino and Stampfer. J Natl Cancer Inst 2010; Ogino et al. Annu Rev Pathol 2019), the GWAS-MPE approach (Ogino et al. Gut 2011), the colorectal continuum model (Yamauchi et al. Gut 2012), the unique disease principle (Ogino et al. Mod Pathol 2013), the etiologic field effect model (Lochhead et al. Mod Pathol 2015), the causal inference-MPE integration (Nishihara et al. Eur J Epidemiol 2015; Liu et al. Eur J Epidemiol 2018), lifecourse-MPE approach (Nishi et al. Am J Prev Med 2015), social MPE (Nishi et al. Expert Rev Mol Diagn 2016), immuno-MPE (immunology-MPE integration) (Ogino et al. Gut 2018), pharmaco-MPE (Ogino et al. npj Precis Oncol 2017), microbiology-MPE integration, MPE-comparative effectiveness research integration, and nutritional MPE. In particular, Dr. Ogino is currently integrating analyses of exposome, germline genetics, tissue microbiota (microbiome), tumor immunity (including immune response to tumor antigens), cancer incidence, and clinical outcomes in large human populations. The lifecourse-MPE approach has substantial potential in research on early-onset cancers including early-onset colorectal cancer (Akimoto et al. Nat Rev Clin Oncol 2021).
One or more keywords matched the following items that are connected to Ogino, Shuji
Item TypeName
Academic Article Commentary: Lifestyle factors and colorectal cancer microsatellite instability--molecular pathological epidemiology science, based on unique tumour principle.
Academic Article Interdisciplinary education to integrate pathology and epidemiology: towards molecular and population-level health science.
Academic Article Ogino et Al. Respond to "the 21st century epidemiologist".
Academic Article Lifestyle factors and microsatellite instability in colorectal cancer: the evolving field of molecular pathological epidemiology.
Academic Article Molecular pathological epidemiology of colorectal neoplasia: an emerging transdisciplinary and interdisciplinary field.
Academic Article Predictors of lymph node count in colorectal cancer resections: data from US nationwide prospective cohort studies.
Academic Article Molecular pathological epidemiology of epigenetics: emerging integrative science to analyze environment, host, and disease.
Concept Epidemiology
Concept Molecular Epidemiology
Academic Article The role of epidemiology in the era of molecular epidemiology and genomics: Summary of the 2013 AJE-sponsored Society of Epidemiologic Research Symposium.
Academic Article Discovery of colorectal cancer PIK3CA mutation as potential predictive biomarker: power and promise of molecular pathological epidemiology.
Academic Article Progress and opportunities in molecular pathological epidemiology of colorectal premalignant lesions.
Academic Article Challenges and opportunities in international molecular cancer prevention research: An ASPO Molecular Epidemiology and the Environment and International Cancer Prevention Interest Groups Report.
Academic Article Proceedings of the second international molecular pathological epidemiology (MPE) meeting.
Academic Article Lifecourse epidemiology and molecular pathological epidemiology.
Academic Article Molecular pathological epidemiology gives clues to paradoxical findings.
Academic Article Integration of molecular pathology, epidemiology and social science for global precision medicine.
Academic Article Review Article: The Role of Molecular Pathological Epidemiology in the Study of Neoplastic and Non-neoplastic Diseases in the Era of Precision Medicine.
Grant Cancer Epidemiology Cohort in Male Health Professionals
Grant The Third International Molecular Pathological Epidemiology (MPE) Meeting
Grant Epigenetic Events and Colorectal Cancer Epidemiology
Grant Molecular Epidemiology of Colorectal Cancer
Grant PROSPECTIVE STUDY OF PANCREATIC CANCER PATHOGENESIS
Grant Prospective Cohort Collaborative in Pancreatic Cancer Epidemiology &Pathogenesis
Academic Article Molecular pathological epidemiology: new developing frontiers of big data science to study etiologies and pathogenesis.
Grant Molecular pathological epidemiology of colorectal cancer
Academic Article Proceedings of the third international molecular pathological epidemiology (MPE) meeting.
Academic Article Dietary Patterns and Risk of Colorectal Cancer: Analysis by Tumor Location and Molecular Subtypes.
Academic Article Post-colonoscopy colorectal cancer: the key role of molecular pathological epidemiology.
Academic Article Body mass index and risk of colorectal carcinoma subtypes classified by tumor differentiation status.
Academic Article Association Between Inflammatory Diet Pattern and Risk of Colorectal Carcinoma Subtypes Classified by Immune Responses to Tumor.
Academic Article Utility of inverse probability weighting in molecular pathological epidemiology.
Academic Article Insights into Pathogenic Interactions Among Environment, Host, and Tumor at the Crossroads of Molecular Pathology and Epidemiology.
Academic Article Dysbiosis of the gut microbiota and colorectal cancer: the key target of molecular pathological epidemiology.
Academic Article Integration of microbiology, molecular pathology, and epidemiology: a new paradigm to explore the pathogenesis of microbiome-driven neoplasms.
Academic Article Proceedings of the fourth international molecular pathological epidemiology (MPE) meeting.
Academic Article Night-Shift Work Duration and Risk of Colorectal Cancer According to IRS1 and IRS2 Expression.
Grant Accelerating Transdisciplinary Epidemiology of Colorectal Cancer
Grant Interdisciplinary Epidemiologic Consortium to Investigate T-cell Response in Colorectal Cancer
Academic Article The microbiome, genetics, and gastrointestinal neoplasms: the evolving field of molecular pathological epidemiology to analyze the tumor-immune-microbiome interaction.
Academic Article Revisiting social MPE: an integration of molecular pathological epidemiology and social science in the new era of precision medicine.
Search Criteria
  • Epidemiology
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.