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One or more keywords matched the following items that are connected to Sinclair, David
Item TypeName
Academic Article The lifespan extension effects of resveratrol are conserved in the honey bee and may be driven by a mechanism related to caloric restriction.
Academic Article Yeast life-span extension by calorie restriction is independent of NAD fluctuation.
Academic Article Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase.
Academic Article Sirtuins: a conserved key unlocking AceCS activity.
Academic Article Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span.
Academic Article Nampt/PBEF/Visfatin: a regulator of mammalian health and longevity?
Academic Article Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes.
Academic Article Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan.
Academic Article Aging: past, present and future.
Academic Article Dietary restriction: standing up for sirtuins.
Academic Article Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae.
Academic Article Toward a unified theory of caloric restriction and longevity regulation.
Academic Article HST2 mediates SIR2-independent life-span extension by calorie restriction.
Academic Article Impact papers on aging in 2009.
Academic Article A blueprint for developing therapeutic approaches that increase healthspan and delay death.
Academic Article Small molecules that regulate lifespan: evidence for xenohormesis.
Academic Article Caloric restriction and life span determination of yeast cells.
Academic Article MSN2 and MSN4 link calorie restriction and TOR to sirtuin-mediated lifespan extension in Saccharomyces cerevisiae.
Academic Article Sirtuin activators mimic caloric restriction and delay ageing in metazoans.
Academic Article Life-span extension in yeast.
Concept Caloric Restriction
Academic Article Metformin improves healthspan and lifespan in mice.
Academic Article Germline energetics, aging, and female infertility.
Academic Article Studying the replicative life span of yeast cells.
Academic Article Dietary restriction involves NAD? -dependent mechanisms and a shift toward oxidative metabolism.
Academic Article Interventions to Slow Aging in Humans: Are We Ready?
Academic Article Effects of Sex, Strain, and Energy Intake on Hallmarks of Aging in Mice.
Grant Yeast screens for genetic &chemical mimetics of CR
Grant SIRT as a regulator of health and lifespan of mammals
Academic Article Comparing the Effects of Low-Protein and High-Carbohydrate Diets and Caloric Restriction on Brain Aging in Mice.
Academic Article Gut Microbiota Predicts Healthy Late-Life Aging in Male Mice.
Search Criteria
  • Caloric Restriction
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.