Harvard Catalyst Profiles

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One or more keywords matched the following items that are connected to Hung, Deborah
Item TypeName
Academic Article Resuscitation-promoting factors are required for ß-lactam tolerance and the permeability barrier in Mycobacterium tuberculosis.
Academic Article Eradication of bacterial persisters with antibiotic-generated hydroxyl radicals.
Academic Article Independent large scale duplications in multiple M. tuberculosis lineages overlapping the same genomic region.
Academic Article MetaMerge: scaling up genome-scale metabolic reconstructions with application to Mycobacterium tuberculosis.
Academic Article Identification of novel inhibitors of M. tuberculosis growth using whole cell based high-throughput screening.
Academic Article The first synthesis of an epidiselenodiketopiperazine.
Concept Mycobacterium
Concept Mycobacterium smegmatis
Concept Mycobacterium tuberculosis
Academic Article Diarylcoumarins inhibit mycolic acid biosynthesis and kill Mycobacterium tuberculosis by targeting FadD32.
Academic Article Synthesis and structure-activity relationships of phenyl-substituted coumarins with anti-tubercular activity that target FadD32.
Academic Article Identification of novel inhibitors of nonreplicating Mycobacterium tuberculosis using a carbon starvation model.
Academic Article Identification of host-targeted small molecules that restrict intracellular Mycobacterium tuberculosis growth.
Academic Article Mechanisms of ß-lactam killing and resistance in the context of Mycobacterium tuberculosis.
Academic Article Baeyer-Villiger Monooxygenases EthA and MymA Are Required for Activation of Replicating and Non-replicating Mycobacterium tuberculosis Inhibitors.
Grant Elucidation of physiology of non-replicating, drug-tolerant Mycobacterium tubercu
Academic Article Loss of a Class A Penicillin-Binding Protein Alters ß-Lactam Susceptibilities in Mycobacterium tuberculosis.
Academic Article Genomic Analysis of the Evolution of Fluoroquinolone Resistance in Mycobacterium tuberculosis Prior to Tuberculosis Diagnosis.
Academic Article Ribosomal mutations promote the evolution of antibiotic resistance in a multidrug environment.
Academic Article Systematic, multiparametric analysis of Mycobacterium tuberculosis intracellular infection offers insight into coordinated virulence.
Academic Article A small-molecule allosteric inhibitor of Mycobacterium tuberculosis tryptophan synthase.
Grant New targets against tuberculosis
Academic Article Continuous and High-Throughput Electromechanical Lysis of Bacterial Pathogens Using Ion Concentration Polarization.
Academic Article The Expanding Diversity of Mycobacterium tuberculosis Drug Targets.
Academic Article Discovery of heterocyclic replacements for the coumarin core of anti-tubercular FadD32 inhibitors.
Academic Article Rapid identification and phylogenetic classification of diverse bacterial pathogens in a multiplexed hybridization assay targeting ribosomal RNA.
Academic Article Large-scale chemical-genetics yields new M. tuberculosis inhibitor classes.
Academic Article Large-Scale Chemical-Genetic Strategy Enables the Design of Antimicrobial Combination Chemotherapy in Mycobacteria.
Academic Article Hybridization-based capture of pathogen mRNA enables paired host-pathogen transcriptional analysis.
Academic Article Using Proteolytic Hypomorphs to Detect Small Molecule Mechanism of Action.
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  • Mycobacterium
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.