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One or more keywords matched the following items that are connected to Tanzi, Rudolph
Item TypeName
Academic Article Effects of RNA interference-mediated silencing of gamma-secretase complex components on cell sensitivity to caspase-3 activation.
Academic Article Generation of the beta-amyloid peptide and the amyloid precursor protein C-terminal fragment gamma are potentiated by FE65L1.
Academic Article BACE is degraded via the lysosomal pathway.
Academic Article Acyl-coenzyme A: cholesterol acyltransferase modulates the generation of the amyloid beta-peptide.
Academic Article The inhalation anesthetic isoflurane induces a vicious cycle of apoptosis and amyloid beta-protein accumulation.
Academic Article SUMO1 modulates Aß generation via BACE1 accumulation.
Academic Article Depletion of GGA3 stabilizes BACE and enhances beta-secretase activity.
Academic Article Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective.
Academic Article The synaptic Abeta hypothesis of Alzheimer disease.
Academic Article The inhalation anesthetic desflurane induces caspase activation and increases amyloid beta-protein levels under hypoxic conditions.
Academic Article Modulation of A beta adhesiveness and secretase site cleavage by zinc.
Academic Article Caspase activation increases beta-amyloid generation independently of caspase cleavage of the beta-amyloid precursor protein (APP).
Academic Article Inhibitors of beta-amyloid formation based on the beta-secretase cleavage site.
Concept Receptors, N-Methyl-D-Aspartate
Concept Aspartic Acid Endopeptidases
Concept Aspartic Acid
Academic Article Elucidation of the BACE1 regulating factor GGA3 in Alzheimer's disease.
Academic Article Synaptotagmins interact with APP and promote Aß generation.
Academic Article Relationship between ubiquilin-1 and BACE1 in human Alzheimer's disease and APdE9 transgenic mouse brain and cell-based models.
Academic Article Palmitoylated APP Forms Dimers, Cleaved by BACE1.
Academic Article Human Neurospheroid Arrays for In Vitro Studies of Alzheimer's Disease.
Academic Article BACE1 Regulates Proliferation and Neuronal Differentiation of Newborn Cells in the Adult Hippocampus in Mice.
Academic Article Gga3 deletion and a GGA3 rare variant associated with late onset Alzheimer's disease trigger BACE1 accumulation in axonal swellings.
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  • Aspartic Acid
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.