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Local perivascular administration of basic fibroblast growth factor: drug delivery and toxicological evaluation.
Perlecan is required to inhibit thrombosis after deep vascular injury and contributes to endothelial cell-mediated inhibition of intimal hyperplasia.
Resonance energy transfer for assessing the molecular integrity of proteins for local delivery.
Angiogenic potential of perivascularly delivered aFGF in a porcine model of chronic myocardial ischemia.
Controlled and modulated release of basic fibroblast growth factor.
Cellular response to transforming growth factor-beta1 and basic fibroblast growth factor depends on release kinetics and extracellular matrix interactions.
Basic fibroblast growth factor enhances the coupling of intimal hyperplasia and proliferation of vasa vasorum in injured rat arteries.
Local perivascular delivery of basic fibroblast growth factor in patients undergoing coronary bypass surgery: results of a phase I randomized, double-blind, placebo-controlled trial.
Vascular cell-derived heparan sulfate shows coupled inhibition of basic fibroblast growth factor binding and mitogenesis in vascular smooth muscle cells.
Kinetics of basic fibroblast growth factor binding to its receptor and heparan sulfate proteoglycan: a mechanism for cooperactivity.
Transforming growth factor beta 1 stimulates the production of basic fibroblast growth factor binding proteoglycans in Balb/c3T3 cells.
Elevated fibroblast growth factor-2 increases tumor necrosis factor-alpha induced endothelial cell death in high glucose.
Syndecan-4 proteoliposomes enhance fibroblast growth factor-2 (FGF-2)-induced proliferation, migration, and neovascularization of ischemic muscle.
The biologic effects of growth factor-toxin conjugates in models of vascular injury depend on dose, mode of delivery, and animal species.
Therapeutic angiogenesis with basic fibroblast growth factor: technique and early results.
Basic fibroblast growth factor in a porcine model of chronic myocardial ischemia: a comparison of angiographic, echocardiographic and coronary flow parameters.
Glucose modulates basement membrane fibroblast growth factor-2 via alterations in endothelial cell permeability.
Perivascular and intravenous administration of basic fibroblast growth factor: vascular and solid organ deposition.
Basic FGF enhances endothelium-dependent relaxation of the collateral-perfused coronary microcirculation.
Basic fibroblast growth factor improves myocardial function in chronically ischemic porcine hearts.
Receptors, Fibroblast Growth Factor
Fibroblast Growth Factor 1
Fibroblast Growth Factor 2
Fibroblast Growth Factor 3