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One or more keywords matched the following properties of Carman, Christopher
PropertyValue
keywords human immunology
keywords systems Immunology
overview Major Research Interests: Adaptive & Innate Immune Cell Regulation and Trafficking Specialties: Immunology, Inflammation, Vascular Biology, Immunomodulation, Bioengineering, Targeted Therapies Our laboratory investigates the basic molecular and cell biological underpinnings of vascular inflammation and peripheral regulation of immune responses with special emphasis on leukocyte-endothelial interactions. Our studies also implement extensive molecular and cellular engineering approaches toward development of new immuno-modulation strategies for use in inflammatory, autoimmune, allogeneic and cancerous diseases. Recently our studies have further focused on micro-environmental regulation of immunity and development of bioengineering approaches (e.g., in vitro chip, organoid and hypoxia technologies) as innovative platforms for studying tumor biology/immunology and for facilitating drug development. Specific Topics we are currently investigating include: The regulation of immune cell activation and migration Peripheral regulation of adaptive and innate immune responses Immuno-modulation of transplantation, autoimmunity and cancer The cytoskeletal and biomechanical regulation of vascular integrity
Search Criteria
  • Immunology
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.