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One or more keywords matched the following items that are connected to Sodroski, Joseph
Item TypeName
Academic Article A chimeric simian/human immunodeficiency virus expressing a primary patient human immunodeficiency virus type 1 isolate env causes an AIDS-like disease after in vivo passage in rhesus monkeys.
Academic Article Changes in human immunodeficiency virus type 1 envelope glycoproteins responsible for the pathogenicity of a multiply passaged simian-human immunodeficiency virus (SHIV-HXBc2).
Academic Article Stimulation of enveloped virus infection by beta-amyloid fibrils.
Academic Article Conformational changes of gp120 in epitopes near the CCR5 binding site are induced by CD4 and a CD4 miniprotein mimetic.
Academic Article Fine definition of a conserved CCR5-binding region on the human immunodeficiency virus type 1 glycoprotein 120.
Academic Article Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120.
Academic Article Tyrosine-sulfated peptides functionally reconstitute a CCR5 variant lacking a critical amino-terminal region.
Academic Article Contribution of charged amino acids in the CDR2 region of CD4 to HIV-1 gp120 binding.
Academic Article SMM-chemokines: a class of unnatural synthetic molecules as chemical probes of chemokine receptor biology and leads for therapeutic development.
Academic Article Analysis of the interaction of antibodies with a conserved enzymatically deglycosylated core of the HIV type 1 envelope glycoprotein 120.
Academic Article Modifications that stabilize human immunodeficiency virus envelope glycoprotein trimers in solution.
Academic Article Identification of a protein encoded by the vpu gene of HIV-1.
Academic Article Modulation of retroviral restriction and proteasome inhibitor-resistant turnover by changes in the TRIM5alpha B-box 2 domain.
Academic Article Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody.
Academic Article The orphan seven-transmembrane receptor apj supports the entry of primary T-cell-line-tropic and dualtropic human immunodeficiency virus type 1.
Academic Article Characterization of stable, soluble trimers containing complete ectodomains of human immunodeficiency virus type 1 envelope glycoproteins.
Academic Article Target cell-specific determinants of membrane fusion within the human immunodeficiency virus type 1 gp120 third variable region and gp41 amino terminus.
Academic Article Rapid CD4+ T-lymphocyte depletion in rhesus monkeys infected with a simian-human immunodeficiency virus expressing the envelope glycoproteins of a primary dual-tropic Ethiopian Clade C HIV type 1 isolate.
Academic Article CD4-induced T-20 binding to human immunodeficiency virus type 1 gp120 blocks interaction with the CXCR4 coreceptor.
Academic Article Characterization of the outer domain of the gp120 glycoprotein from human immunodeficiency virus type 1.
Academic Article CD4-independent binding of SIV gp120 to rhesus CCR5.
Academic Article Characterization of a discontinuous human immunodeficiency virus type 1 gp120 epitope recognized by a broadly reactive neutralizing human monoclonal antibody.
Academic Article Retrovirus restriction by TRIM5alpha variants from Old World and New World primates.
Academic Article Functional regions of the envelope glycoprotein of human immunodeficiency virus type 1.
Academic Article Structures of the CCR5 N terminus and of a tyrosine-sulfated antibody with HIV-1 gp120 and CD4.
Academic Article The T open reading frame of human immunodeficiency virus type 1.
Academic Article Human anti-V2 monoclonal antibody that neutralizes primary but not laboratory isolates of human immunodeficiency virus type 1.
Academic Article Immunological evidence for interactions between the first, second, and fifth conserved domains of the gp120 surface glycoprotein of human immunodeficiency virus type 1.
Academic Article Effect of amino acid changes in the V1/V2 region of the human immunodeficiency virus type 1 gp120 glycoprotein on subunit association, syncytium formation, and recognition by a neutralizing antibody.
Academic Article Oligomer-specific conformations of the human immunodeficiency virus (HIV-1) gp41 envelope glycoprotein ectodomain recognized by human monoclonal antibodies.
Academic Article Enhanced autointegration in hyperstable simian immunodeficiency virus capsid mutants blocked after reverse transcription.
Academic Article Monoclonal antibodies to HIV-1 gp120: a request.
Academic Article Enhanced expression, native purification, and characterization of CCR5, a principal HIV-1 coreceptor.
Academic Article Characterization of primary isolate-like variants of simian-human immunodeficiency virus.
Academic Article Human immunodeficiency virus type 1 gp120 envelope glycoprotein regions important for association with the gp41 transmembrane glycoprotein.
Academic Article Structure of a V3-containing HIV-1 gp120 core.
Academic Article Blockade of HIV-1 infection of New World monkey cells occurs primarily at the stage of virus entry.
Academic Article Effects of changes in gp120-CD4 binding affinity on human immunodeficiency virus type 1 envelope glycoprotein function and soluble CD4 sensitivity.
Academic Article Analysis of the neutralizing antibody response elicited in rabbits by repeated inoculation with trimeric HIV-1 envelope glycoproteins.
Academic Article Structural basis of immune evasion at the site of CD4 attachment on HIV-1 gp120.
Academic Article Structure of HIV-1 gp120 with gp41-interactive region reveals layered envelope architecture and basis of conformational mobility.
Academic Article TRIM5alpha Modulates Immunodeficiency Virus Control in Rhesus Monkeys.
Academic Article Increased neutralization sensitivity of CD4-independent human immunodeficiency virus variants.
Academic Article Exploring the stereochemistry of CXCR4-peptide recognition and inhibiting HIV-1 entry with D-peptides derived from chemokines.
Academic Article Two surface-exposed elements of the B30.2/SPRY domain as potency determinants of N-tropic murine leukemia virus restriction by human TRIM5alpha.
Academic Article The 3' region of bovine leukemia virus genome encodes a trans-activator protein.
Academic Article Characterization of conserved human immunodeficiency virus type 1 gp120 neutralization epitopes exposed upon gp120-CD4 binding.
Academic Article gp120-independent fusion mediated by the human immunodeficiency virus type 1 gp41 envelope glycoprotein: a reassessment.
Academic Article The ability of multimerized cyclophilin A to restrict retrovirus infection.
Academic Article The HIV-1 gp120 major variable regions modulate cold inactivation.
Academic Article Antigens encoded by the 3'-terminal region of human T-cell leukemia virus: evidence for a functional gene.
Academic Article High degree of sensitivity of the simian immunodeficiency virus (SIVmac) envelope glycoprotein subunit association to amino acid changes in the glycoprotein 41 ectodomain.
Academic Article Two orphan seven-transmembrane segment receptors which are expressed in CD4-positive cells support simian immunodeficiency virus infection.
Academic Article Structures of HIV-1 gp120 envelope glycoproteins from laboratory-adapted and primary isolates.
Academic Article Sialylated O-glycans and sulfated tyrosines in the NH2-terminal domain of CC chemokine receptor 5 contribute to high affinity binding of chemokines.
Academic Article Fitness costs limit viral escape from cytotoxic T lymphocytes at a structurally constrained epitope.
Academic Article An unrelated monoclonal antibody neutralizes human immunodeficiency virus type 1 by binding to an artificial epitope engineered in a functionally neutral region of the viral envelope glycoproteins.
Academic Article Characterization of the cDNA of a broadly reactive neutralizing human anti-gp120 monoclonal antibody.
Academic Article A tyrosine-sulfated peptide based on the N terminus of CCR5 interacts with a CD4-enhanced epitope of the HIV-1 gp120 envelope glycoprotein and inhibits HIV-1 entry.
Academic Article Attenuation of human immunodeficiency virus type 1 cytopathic effect by a mutation affecting the transmembrane envelope glycoprotein.
Academic Article Induction of antibodies in guinea pigs and rhesus monkeys against the human immunodeficiency virus type 1 envelope: neutralization of nonpathogenic and pathogenic primary isolate simian/human immunodeficiency virus strains.
Academic Article The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys.
Academic Article Binding and susceptibility to postentry restriction factors in monkey cells are specified by distinct regions of the human immunodeficiency virus type 1 capsid.
Academic Article Identification and characterization of monoclonal antibodies specific for polymorphic antigenic determinants within the V2 region of the human immunodeficiency virus type 1 envelope glycoprotein.
Academic Article Role of vif in replication of human immunodeficiency virus type 1 in CD4+ T lymphocytes.
Academic Article Stabilization of human immunodeficiency virus type 1 envelope glycoprotein trimers by disulfide bonds introduced into the gp41 glycoprotein ectodomain.
Academic Article Tyrosine sulfation of the amino terminus of CCR5 facilitates HIV-1 entry.
Academic Article Tyrosine sulfation of human antibodies contributes to recognition of the CCR5 binding region of HIV-1 gp120.
Academic Article Flexible use of nuclear import pathways by HIV-1.
Academic Article Antibodies to CD4 in individuals infected with human immunodeficiency virus type 1.
Academic Article A V3 loop-dependent gp120 element disrupted by CD4 binding stabilizes the human immunodeficiency virus envelope glycoprotein trimer.
Academic Article T cell receptor V beta repertoire in an acute infection of rhesus monkeys with simian immunodeficiency viruses and a chimeric simian-human immunodeficiency virus.
Academic Article Phenotypic knockout of the high-affinity human interleukin 2 receptor by intracellular single-chain antibodies against the alpha subunit of the receptor.
Academic Article Structural characterization of broadly neutralizing human monoclonal antibodies against the CD4 binding site of HIV-1 gp120.
Academic Article Species-specific variation in the B30.2(SPRY) domain of TRIM5alpha determines the potency of human immunodeficiency virus restriction.
Academic Article Expression of the art gene protein of human T-lymphotropic virus type III (HTLV-III/LAV) in bacteria.
Academic Article Functional mimicry of a human immunodeficiency virus type 1 coreceptor by a neutralizing monoclonal antibody.
Academic Article The B30.2(SPRY) domain of the retroviral restriction factor TRIM5alpha exhibits lineage-specific length and sequence variation in primates.
Academic Article Different stereochemical requirements for CXCR4 binding and signaling functions as revealed by an anti-HIV, D-amino acid-containing SMM-chemokine ligand.
Academic Article Changes in the transmembrane region of the human immunodeficiency virus type 1 gp41 envelope glycoprotein affect membrane fusion.
Academic Article Probing the structure of the human immunodeficiency virus surface glycoprotein gp120 with a panel of monoclonal antibodies.
Academic Article Structural basis for broad and potent neutralization of HIV-1 by antibody VRC01.
Academic Article Serological cross-reactivity between envelope gene products of type I and type II human T-cell leukemia virus.
Academic Article Sequence of the envelope glycoprotein gene of type II human T lymphotropic virus.
Academic Article Amino acid sequence requirements for the incorporation of the Vpx protein of simian immunodeficiency virus into virion particles.
Academic Article Lineage-specific differences between human and simian immunodeficiency virus regulation of gp120 trimer association and CD4 binding.
Academic Article Major glycoprotein antigens that induce antibodies in AIDS patients are encoded by HTLV-III.
Academic Article Involvement of the V1/V2 variable loop structure in the exposure of human immunodeficiency virus type 1 gp120 epitopes induced by receptor binding.
Academic Article Human monoclonal antibody 2G12 defines a distinctive neutralization epitope on the gp120 glycoprotein of human immunodeficiency virus type 1.
Academic Article Molecular cloning and analysis of functional envelope genes from human immunodeficiency virus type 1 sequence subtypes A through G. The WHO and NIAID Networks for HIV Isolation and Characterization.
Academic Article Neutralization sensitivity of a simian-human immunodeficiency virus (SHIV-HXBc2P 3.2N) isolated from an infected rhesus macaque with neurological disease.
Academic Article Structural interactions between chemokine receptors, gp120 Env and CD4.
Academic Article Adaptation of human immunodeficiency virus type 1 to cells expressing a binding-deficient CD4 mutant (lysine 46 to aspartic acid).
Academic Article Towards a structure of the HIV-1 envelope glycoprotein gp120: an immunochemical approach.
Academic Article Complex determinants within the Moloney murine leukemia virus capsid modulate susceptibility of the virus to Fv1 and Ref1-mediated restriction.
Academic Article Antigenic variation in gp120s from molecular clones of HIV-1 LAI.
Academic Article Human antibody responses to HIV type 1 glycoprotein 41 cloned in phage display libraries suggest three major epitopes are recognized and give evidence for conserved antibody motifs in antigen binding.
Academic Article Apelin, the natural ligand of the orphan seven-transmembrane receptor APJ, inhibits human immunodeficiency virus type 1 entry.
Academic Article Identification of membrane anchorage domains of the HIV-1 gp160 envelope glycoprotein precursor.
Academic Article Identification of individual human immunodeficiency virus type 1 gp120 amino acids important for CD4 receptor binding.
Academic Article Persistent infection of macaques with simian-human immunodeficiency viruses.
Academic Article Neutralizing recombinant human antibodies to a conformational V2- and CD4-binding site-sensitive epitope of HIV-1 gp120 isolated by using an epitope-masking procedure.
Concept Amino Acid Sequence
Academic Article A twin-cysteine motif in the V2 region of gp120 is associated with SIV envelope trimer stabilization.
Academic Article Contribution of glutamine residues in the helix 4-5 loop to capsid-capsid interactions in simian immunodeficiency virus of macaques.
Academic Article Comparative Analysis of the Glycosylation Profiles of Membrane-Anchored HIV-1 Envelope Glycoprotein Trimers and Soluble gp140.
Academic Article Amino Acid Changes in the HIV-1 gp41 Membrane Proximal Region Control Virus Neutralization Sensitivity.
Academic Article Co-receptor Binding Site Antibodies Enable CD4-Mimetics to Expose Conserved Anti-cluster A ADCC Epitopes on HIV-1 Envelope Glycoproteins.
Academic Article Influence of the Envelope gp120 Phe 43 Cavity on HIV-1 Sensitivity to Antibody-Dependent Cell-Mediated Cytotoxicity Responses.
Academic Article Glycosylation Benchmark Profile for HIV-1 Envelope Glycoprotein Production Based on Eleven Env Trimers.
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  • Amino Acid Sequence
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.