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A transglutaminase homologue as a condensation catalyst in antibiotic assembly lines.
A ketoreductase domain in the PksJ protein of the bacillaene assembly line carries out both alpha- and beta-ketone reduction during chain growth.
Directed evolution can rapidly improve the activity of chimeric assembly-line enzymes.
Andrimid producers encode an acetyl-CoA carboxyltransferase subunit resistant to the action of the antibiotic.
Gatekeeping versus promiscuity in the early stages of the andrimid biosynthetic assembly line.
The identification of bacillaene, the product of the PksX megacomplex in Bacillus subtilis.