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Coumarin formation in novobiocin biosynthesis: beta-hydroxylation of the aminoacyl enzyme tyrosyl-S-NovH by a cytochrome P450 NovI.
Antibiotic glycosyltransferases: antibiotic maturation and prospects for reprogramming.
The antibiotic microcin B17 is a DNA gyrase poison: characterisation of the mode of inhibition.
Characterization of the formation of the pyrrole moiety during clorobiocin and coumermycin A1 biosynthesis.
Assembly of dimeric variants of coumermycins by tandem action of the four biosynthetic enzymes CouL, CouM, CouP, and NovN.
Characterization of the aminocoumarin ligase SimL from the simocyclinone pathway and tandem incubation with NovM,P,N from the novobiocin pathway.
CloQ, a prenyltransferase involved in clorobiocin biosynthesis.
Synthesis of proposed oxidation-cyclization-methylation intermediates of the coumarin antibiotic biosynthetic pathway.