Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Search Result Details

This page shows the details of why an item matched the keywords from your search.
One or more keywords matched the following items that are connected to Kahn, C.
Item TypeName
Academic Article Association of insulin receptor substrate 1 (IRS-1) y895 with Grb-2 mediates the insulin signaling involved in IRS-1-deficient brown adipocyte mitogenesis.
Academic Article Insulin receptor substrate 3 (IRS-3) and IRS-4 impair IRS-1- and IRS-2-mediated signaling.
Academic Article Postnatal growth responses to insulin-like growth factor I in insulin receptor substrate-1-deficient mice.
Academic Article Deletion of Shp2 tyrosine phosphatase in muscle leads to dilated cardiomyopathy, insulin resistance, and premature death.
Academic Article Central insulin action regulates peripheral glucose and fat metabolism in mice.
Academic Article Impaired sodium excretion and increased blood pressure in mice with targeted deletion of renal epithelial insulin receptor.
Academic Article Altered signaling and cell cycle regulation in embryonal stem cells with a disruption of the gene for phosphoinositide 3-kinase regulatory subunit p85alpha.
Academic Article Loss of skeletal muscle HIF-1alpha results in altered exercise endurance.
Academic Article Identification of interactive loci linked to insulin and leptin in mice with genetic insulin resistance.
Academic Article Targeted deletion of AIF decreases mitochondrial oxidative phosphorylation and protects from obesity and diabetes.
Concept Gene Deletion
Academic Article Loss of Akt1 in mice increases energy expenditure and protects against diet-induced obesity.
Academic Article Reduction of the cholesterol sensor SCAP in the brains of mice causes impaired synaptic transmission and altered cognitive function.
Academic Article Sirt3 regulates metabolic flexibility of skeletal muscle through reversible enzymatic deacetylation.
Academic Article Insulin and IGF-1 receptors regulate FoxO-mediated signaling in muscle proteostasis.
Academic Article Adipocyte Dynamics and Reversible Metabolic Syndrome in Mice with an Inducible Adipocyte-Specific Deletion of the Insulin Receptor.
Search Criteria
  • Gene Deletion
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.