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One or more keywords matched the following items that are connected to Kahn, C.
Item TypeName
Academic Article Divergent regulation of the Glut 1 and Glut 4 glucose transporters in isolated adipocytes from Zucker rats.
Academic Article Association of insulin receptor substrate 1 (IRS-1) y895 with Grb-2 mediates the insulin signaling involved in IRS-1-deficient brown adipocyte mitogenesis.
Academic Article Insulin induces the phosphorylation of DNA-binding nuclear proteins including lamins in 3T3-F442A.
Academic Article Tissue-specific insulin resistance in mice with mutations in the insulin receptor, IRS-1, and IRS-2.
Academic Article Atypical beta-adrenergic effects on insulin signaling and action in beta(3)-adrenoceptor-deficient brown adipocytes.
Academic Article Insulin and the beta3-adrenoceptor differentially regulate uncoupling protein-1 expression.
Academic Article Role of brain insulin receptor in control of body weight and reproduction.
Academic Article Glucose toxicity and the development of diabetes in mice with muscle-specific inactivation of GLUT4.
Academic Article Differential roles of the insulin and insulin-like growth factor-I (IGF-I) receptors in response to insulin and IGF-I.
Academic Article Increased insulin sensitivity in IGF-I receptor--deficient brown adipocytes.
Academic Article High fat feeding causes insulin resistance and a marked decrease in the expression of glucose transporters (Glut 4) in fat cells of rats.
Academic Article Insulin-induced up-regulated uncoupling protein-1 expression is mediated by insulin receptor substrate 1 through the phosphatidylinositol 3-kinase/Akt signaling pathway in fetal brown adipocytes.
Academic Article Insulin substrates 1 and 2 are corequired for activation of atypical protein kinase C and Cbl-dependent phosphatidylinositol 3-kinase during insulin action in immortalized brown adipocytes.
Academic Article Beneficial effects of subcutaneous fat transplantation on metabolism.
Academic Article New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure.
Academic Article Bi-directional regulation of brown fat adipogenesis by the insulin receptor.
Academic Article Tissue-specific ablation of the GLUT4 glucose transporter or the insulin receptor challenges assumptions about insulin action and glucose homeostasis.
Academic Article Ectopic brown adipose tissue in muscle provides a mechanism for differences in risk of metabolic syndrome in mice.
Academic Article Mitochondrial gene expression and increased oxidative metabolism: role in increased lifespan of fat-specific insulin receptor knock-out mice.
Academic Article Cold but not sympathomimetics activates human brown adipose tissue in vivo.
Academic Article SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation.
Academic Article Novel adipocyte lines from brown fat: a model system for the study of differentiation, energy metabolism, and insulin action.
Academic Article Extended longevity in mice lacking the insulin receptor in adipose tissue.
Academic Article The Gordon Wilson Lecture. Lessons about the control of glucose homeostasis and the pathogenesis of diabetes from knockout mice.
Academic Article Essential role of insulin receptor substrate-2 in insulin stimulation of Glut4 translocation and glucose uptake in brown adipocytes.
Academic Article Characterization of the Met326Ile variant of phosphatidylinositol 3-kinase p85alpha.
Academic Article Adipose tissue selective insulin receptor knockout protects against obesity and obesity-related glucose intolerance.
Academic Article Mitochondrial proton leak in obesity-resistant and obesity-prone mice.
Academic Article Central insulin action regulates peripheral glucose and fat metabolism in mice.
Academic Article Impaired thermogenesis and adipose tissue development in mice with fat-specific disruption of insulin and IGF-1 signalling.
Academic Article IRS-1 transgenic mice show increased epididymal fat mass and insulin resistance.
Academic Article Adipose depots possess unique developmental gene signatures.
Academic Article Cellular and molecular mechanisms of adipose tissue plasticity in muscle insulin receptor knockout mice.
Academic Article Anatomical and functional assessment of brown adipose tissue by magnetic resonance imaging.
Academic Article Retinaldehyde dehydrogenase 1 regulates a thermogenic program in white adipose tissue.
Academic Article Identification and importance of brown adipose tissue in adult humans.
Academic Article Mir193b-365 is essential for brown fat differentiation.
Academic Article Brown fat as a therapy for obesity and diabetes.
Academic Article Adipose-specific deletion of TFAM increases mitochondrial oxidation and protects mice against obesity and insulin resistance.
Academic Article Insulin signalling and the regulation of glucose and lipid metabolism.
Academic Article Insulin signaling in insulin receptor substrate (IRS)-1-deficient brown adipocytes: requirement of IRS-1 for lipid synthesis.
Academic Article Redistribution of substrates to adipose tissue promotes obesity in mice with selective insulin resistance in muscle.
Academic Article Hypoglycaemia, liver necrosis and perinatal death in mice lacking all isoforms of phosphoinositide 3-kinase p85 alpha.
Academic Article Developmental and hormonal signals dramatically alter the localization and abundance of insulin receptor substrate proteins in the mammary gland.
Academic Article Glucose homeostasis and tissue transcript content of insulin signaling intermediates in four inbred strains of mice: C57BL/6, C57BLKS/6, DBA/2, and 129X1.
Academic Article Essential role of insulin receptor substrate 1 in differentiation of brown adipocytes.
Academic Article Prediction of preadipocyte differentiation by gene expression reveals role of insulin receptor substrates and necdin.
Academic Article Transplantation of adipose tissue and stem cells: role in metabolism and disease.
Academic Article Lessons on conditional gene targeting in mouse adipose tissue.
Academic Article p50alpha/p55alpha phosphoinositide 3-kinase knockout mice exhibit enhanced insulin sensitivity.
Academic Article Insulin inhibits pertussis toxin-catalyzed ADP-ribosylation of G-proteins. Evidence for a novel interaction between insulin receptors and G-proteins.
Academic Article Brown adipose tissue-specific insulin receptor knockout shows diabetic phenotype without insulin resistance.
Academic Article GLUT4, AMP kinase, but not the insulin receptor, are required for hepatoportal glucose sensor-stimulated muscle glucose utilization.
Academic Article Cellular bioenergetics as a target for obesity therapy.
Academic Article Mitochondria, obesity and aging.
Academic Article Differential roles of insulin receptor substrates in brown adipocyte differentiation.
Academic Article Divergent regulation of hepatic glucose and lipid metabolism by phosphoinositide 3-kinase via Akt and PKClambda/zeta.
Academic Article Developmental origin of fat: tracking obesity to its source.
Academic Article Medicine. Can we nip obesity in its vascular bud?
Academic Article Sex and depot differences in adipocyte insulin sensitivity and glucose metabolism.
Academic Article Intrinsic heterogeneity in adipose tissue of fat-specific insulin receptor knock-out mice is associated with differences in patterns of gene expression.
Academic Article Knockout models are useful tools to dissect the pathophysiology and genetics of insulin resistance.
Academic Article Lipoatrophic diabetes in Irs1(-/-)/Irs3(-/-) double knockout mice.
Academic Article Mosaic analysis of insulin receptor function.
Academic Article Reduced expression of the NADPH oxidase NOX4 is a hallmark of adipocyte differentiation.
Academic Article The role and importance of brown adipose tissue in energy homeostasis.
Academic Article Role of microRNA processing in adipose tissue in stress defense and longevity.
Academic Article Calorie restriction increases insulin-stimulated glucose transport in skeletal muscle from IRS-1 knockout mice.
Academic Article Muscle-specific PPARgamma-deficient mice develop increased adiposity and insulin resistance but respond to thiazolidinediones.
Academic Article Brain glucagon-like peptide-1 increases insulin secretion and muscle insulin resistance to favor hepatic glycogen storage.
Academic Article Evidence for a role of developmental genes in the origin of obesity and body fat distribution.
Academic Article Alterations in insulin receptor autophosphorylation in insulin resistance: correlation with altered sensitivity to glucose transport and antilipolysis to insulin.
Academic Article Dietary leucine--an environmental modifier of insulin resistance acting on multiple levels of metabolism.
Concept Adipose Tissue, Brown
Concept Body Fat Distribution
Concept Adipose Tissue, White
Concept Adipose Tissue
Academic Article Vascular endothelial growth factor is important for brown adipose tissue development and maintenance.
Academic Article Measurement of human brown adipose tissue volume and activity using anatomic MR imaging and functional MR imaging.
Academic Article Thioesterase superfamily member 2/Acyl-CoA thioesterase 13 (Them2/Acot13) regulates adaptive thermogenesis in mice.
Academic Article Insulin receptor signaling in normal and insulin-resistant states.
Academic Article Interplay between FGF21 and insulin action in the liver regulates metabolism.
Academic Article Adipose tissue mitochondrial dysfunction triggers a lipodystrophic syndrome with insulin resistance, hepatosteatosis, and cardiovascular complications.
Academic Article Insulin and insulin-like growth factor 1 receptors are required for normal expression of imprinted genes.
Academic Article CDK4 is an essential insulin effector in adipocytes.
Academic Article Dysfunctional Subcutaneous Fat With Reduced Dicer and Brown Adipose Tissue Gene Expression in HIV-Infected Patients.
Academic Article Essential Role of IGFIR in the Onset of Male Brown Fat Thermogenic Function: Regulation of Glucose Homeostasis by Differential Organ-Specific Insulin Sensitivity.
Academic Article Fat-specific Dicer deficiency accelerates aging and mitigates several effects of dietary restriction in mice.
Academic Article Differential Roles of Insulin and IGF-1 Receptors in Adipose Tissue Development and Function.
Academic Article Lipodystrophy Due to Adipose Tissue-Specific Insulin Receptor Knockout Results in Progressive NAFLD.
Academic Article Adipocyte Dynamics and Reversible Metabolic Syndrome in Mice with an Inducible Adipocyte-Specific Deletion of the Insulin Receptor.
Academic Article Adipose-derived circulating miRNAs regulate gene expression in other tissues.
Academic Article Impairment of insulin signalling in peripheral tissue fails to extend murine lifespan.
Academic Article Pyruvate induces torpor in obese mice.
Academic Article Distinct signalling properties of insulin receptor substrate (IRS)-1 and IRS-2 in mediating insulin/IGF-1 action.
Academic Article Developmental and functional heterogeneity of white adipocytes within a single fat depot.
Academic Article Brown adipose tissue-specific insulin receptor knockout shows diabetic phenotype without insulin resistance.
Academic Article Insulin signaling in the hippocampus and amygdala regulates metabolism and neurobehavior.
Academic Article Membrane metallo-endopeptidase (Neprilysin) regulates inflammatory response and insulin signaling in white preadipocytes.
Academic Article Regulation of UCP1 and Mitochondrial Metabolism in Brown Adipose Tissue by Reversible Succinylation.
Academic Article Extracellular miRNAs: From Biomarkers to Mediators of Physiology and Disease.
Academic Article Altered adipose tissue and adipocyte function in the pathogenesis of metabolic syndrome.
Academic Article FGF6 and FGF9 regulate UCP1 expression independent of brown adipogenesis.
Academic Article Dynamic changes in DICER levels in adipose tissue control metabolic adaptations to exercise.
Search Criteria
  • Adipose Tissue
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.