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One or more keywords matched the following items that are connected to Sayegh, Mohamed
Item TypeName
Academic Article Induction of "infectious" tolerance to MHC-incompatible cardiac allografts in CD4 monoclonal antibody-treated sensitized rat recipients.
Academic Article Mechanisms of indirect allorecognition in graft rejection: class II MHC allopeptide-specific T cell clones transfer delayed-type hypersensitivity responses in vivo.
Academic Article CD4-targeted therapy and CD28-B7 costimulatory blockage may independently induce tolerance in sensitized allograft recipients.
Academic Article CD4-targeted therapy induces "infectious" tolerance to cardiac allografts in sensitized rat recipients.
Academic Article Importance of the CD28/B7 costimulatory pathway in the development of chronic ductopenic rejection in a new model of orthotopic rat liver allotransplantation.
Academic Article Evidence that therapeutic strategies targeted at CD4+ cells modulate accelerated rejection of cardiac allografts in sensitized rats by different mechanisms.
Academic Article Blocking of mononuclear cell accumulation, cytokine production, and endothelial activation within rat cardiac allografts by CD4 monoclonal antibody therapy.
Academic Article Class II MHC allopeptide-specific T-cell clones transfer delayed type hypersensitivity responses in vivo.
Academic Article Therapeutic strategies targeted at CD4+ cells obviate accelerated rejection of cardiac allografts in sensitized rats.
Academic Article Type 2 helper T cell-type cytokines and the development of "infectious" tolerance in rat cardiac allograft recipients.
Academic Article CD28-B7 T cell costimulatory blockade by CTLA4Ig in sensitized rat recipients: induction of transplantation tolerance in association with depressed cell-mediated and humoral immune responses.
Academic Article CD28-B7 T-cell co-stimulatory blockade potentiates the effects of intrathymic immunomodulation in sensitized graft recipients.
Academic Article Effects of leflunomide and deoxyspergualin in the guinea pig-->rat cardiac model of delayed xenograft rejection: suppression of B cell and C-C chemokine responses but not induction of macrophage lectin.
Academic Article Agonistic and antagonistic interactions between CTLA4Ig and donor alloantigens in sensitized rat recipients of cardiac allografts.
Academic Article CD28-B7 blockade after alloantigenic challenge in vivo inhibits Th1 cytokines but spares Th2.
Academic Article Blocking cell microtubule assembly inhibits the alloimmune response in vitro and prolongs renal allograft survival by inhibition of Th1 and sparing of Th2 cell function in vivo.
Academic Article Rat intestinal epithelial cells present major histocompatibility complex allopeptides to primed T cells.
Academic Article CD28-B7 T cell costimulatory blockade by CTLA4Ig in the rat renal allograft model: inhibition of cell-mediated and humoral immune responses in vivo.
Academic Article Distinct tolerance pathways in sensitized allograft recipients after selective blockade of activation signal 1 or signal 2.
Academic Article Induction of immunity and oral tolerance with polymorphic class II major histocompatibility complex allopeptides in the rat.
Academic Article Anti-CD4 monoclonal antibody effects cellular hyporesponsiveness and prolongs renal allograft survival in the rat.
Academic Article Abrogation of accelerated allograft rejection by intrathymic injection of donor spleen cells is associated with upregulation of donor-reactive IgM, IgG1, and IgG2A, but depression of IgG2B in the circulation and at the graft site.
Academic Article Intrathymic injection of donor-specific X-irradiation-sensitive spleen cells abrogates accelerated rejection of cardiac allografts in sensitized rats.
Academic Article Induction of immunity and oral tolerance to alloantigen by polymorphic class II major histocompatibility complex allopeptides in the rat.
Academic Article Thymic recognition of class II major histocompatibility complex allopeptides induces donor-specific unresponsiveness to renal allografts.
Academic Article Mesenteric and intraepithelial lymphocytes are insufficient to cause rejection but able to mediate lethal graft-versus-host disease in small bowel transplants.
Academic Article CD4 mAb therapy modulates alloantibody production and intracardiac graft deposition in association with selective inhibition of Th1 lymphokines.
Academic Article Inhibition of CD26/dipeptidyl peptidase IV activity in vivo prolongs cardiac allograft survival in rat recipients.
Academic Article In vivo evidence for the Th1/Th2 paradigm: oral alloantigen-induced modulation of accelerated allograft rejection is associated with dense intragraft IL-4.
Academic Article Distinct tolerance pathways in sensitized rat recipients after blockade of activation signal 1 and signal 2.
Academic Article Th2-type cytokines in the "infectious" tolerance pathway.
Academic Article The alloantibody network following intrathymic immunomodulation of sensitized rat recipients of cardiac allografts.
Academic Article Inhibition of the alloimmune response with synthetic nonpolymorphic class II MHC peptides.
Academic Article Oral, but not intravenous, alloantigen prevents accelerated allograft rejection by selective intragraft Th2 cell activation.
Academic Article Intrathymic immunomodulation in sensitized rat recipients of cardiac allografts: requirements for allorecognition pathways.
Academic Article The effects of nondepleting CD4 targeted therapy in presensitized rat recipients of cardiac allografts.
Academic Article Intrathymic injection of allogeneic cells induces indefinite survival of cardiac but not small bowel grafts.
Concept Rats, Inbred BN
Search Criteria
  • Rats Inbred BN
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.