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One or more keywords matched the following items that are connected to Sayegh, Mohamed
Item TypeName
Academic Article Role of indirect allorecognition in allograft rejection.
Academic Article New TCR transgenic model for tracking allospecific CD4 T-cell activation and tolerance in vivo.
Academic Article Cytokine analysis of human renal allograft aspiration biopsy cultures supernatants predicts acute rejection.
Academic Article Defining Th1 and Th2 immune responses in a reciprocal cytokine environment in vivo.
Academic Article Quantifying the frequency of alloreactive T cells in vivo: new answers to an old question.
Academic Article Differential role of CCR2 in islet and heart allograft rejection: tissue specificity of chemokine/chemokine receptor function in vivo.
Academic Article Neural stem/progenitor cells express costimulatory molecules that are differentially regulated by inflammatory and apoptotic stimuli.
Academic Article Differential role of programmed death-ligand 1 [corrected] and programmed death-ligand 2 [corrected] in regulating the susceptibility and chronic progression of experimental autoimmune encephalomyelitis.
Academic Article Both CD80 and CD86 co-stimulatory molecules regulate allergic pulmonary inflammation.
Academic Article Blocking of mononuclear cell accumulation, cytokine production, and endothelial activation within rat cardiac allografts by CD4 monoclonal antibody therapy.
Academic Article IL-21 is an antitolerogenic cytokine of the late-phase alloimmune response.
Academic Article Physiological mechanisms of regulating alloimmunity: cytokines, CTLA-4, CD25+ cells, and the alloreactive T cell clone size.
Academic Article Mechanisms of tolerance induced by donor-specific transfusion and ICOS-B7h blockade in a model of CD4+ T-cell-mediated allograft rejection.
Academic Article Costimulatory function and expression of CD40 ligand, CD80, and CD86 in vascularized murine cardiac allograft rejection.
Academic Article Type 2 helper T cell-type cytokines and the development of "infectious" tolerance in rat cardiac allograft recipients.
Academic Article Kinetics of expression of costimulatory molecules and their ligands in murine relapsing experimental autoimmune encephalomyelitis in vivo.
Academic Article Assessment by flow cytometry of intracellular cytokine production in the peripheral blood cells of renal transplant recipients.
Academic Article Beta 3 integrins regulate lymphocyte migration and cytokine responses in heart transplant rejection.
Academic Article Targeting signal 1 through CD45RB synergizes with CD40 ligand blockade and promotes long term engraftment and tolerance in stringent transplant models.
Academic Article A novel CD154 monoclonal antibody in acute and chronic rat vascularized cardiac allograft rejection.
Academic Article Congenic mesenchymal stem cell therapy reverses hyperglycemia in experimental type 1 diabetes.
Academic Article CD28-B7 blockade after alloantigenic challenge in vivo inhibits Th1 cytokines but spares Th2.
Academic Article Blocking cell microtubule assembly inhibits the alloimmune response in vitro and prolongs renal allograft survival by inhibition of Th1 and sparing of Th2 cell function in vivo.
Academic Article Upregulation of cytokines associated with macrophage activation in the Lewis-to-F344 rat transplantation model of chronic cardiac rejection.
Academic Article A novel clinically relevant strategy to abrogate autoimmunity and regulate alloimmunity in NOD mice.
Academic Article Differential effects of oral versus intrathymic administration of polymorphic major histocompatibility complex class II peptides on mononuclear and endothelial cell activation and cytokine expression during a delayed-type hypersensitivity response.
Academic Article Distinct tolerance pathways in sensitized allograft recipients after selective blockade of activation signal 1 or signal 2.
Academic Article The role of CC chemokine receptor 5 (CCR5) in islet allograft rejection.
Academic Article Comparative studies of specific acquired systemic tolerance induced by intrathymic inoculation of a single synthetic Wistar-Furth (RT1U) allo-MHC class I (RT1.AU) peptide or WAG (RT1U)-derived class I peptide.
Academic Article The role of the ICOS-B7h T cell costimulatory pathway in transplantation immunity.
Academic Article Tissue expression of PD-L1 mediates peripheral T cell tolerance.
Academic Article In vivo evidence for the Th1/Th2 paradigm: oral alloantigen-induced modulation of accelerated allograft rejection is associated with dense intragraft IL-4.
Academic Article Effects of explosive brain death on cytokine activation of peripheral organs in the rat.
Academic Article Distinct tolerance pathways in sensitized rat recipients after blockade of activation signal 1 and signal 2.
Academic Article Th1 cytokines, programmed cell death, and alloreactive T cell clone size in transplant tolerance.
Academic Article Novel insights into the mechanism of action of FTY720 in a transgenic model of allograft rejection: implications for therapy of chronic rejection.
Academic Article Mechanisms of acquired thymic tolerance in vivo: intrathymic injection of antigen induces apoptosis of thymocytes and peripheral T cell anergy.
Academic Article Prolongation of survival and preservation of allograft structure and function by a signaling CD28 mAB in a rat model of chronic kidney rejection.
Academic Article Th2-type cytokines in the "infectious" tolerance pathway.
Academic Article In vitro and in vivo immunomodulatory effects of RDP1258, a novel synthetic peptide.
Academic Article The role of CD154-CD40 versus CD28-B7 costimulatory pathways in regulating allogeneic Th1 and Th2 responses in vivo.
Academic Article Endothelin in organ transplantation.
Academic Article The in vivo mechanism of action of CTLA4Ig.
Academic Article Oral, but not intravenous, alloantigen prevents accelerated allograft rejection by selective intragraft Th2 cell activation.
Academic Article Inhibition of CD28-B7 T-cell costimulatory activation pathway affects intragraft cytokine and growth factor expression in chronic renal allograft rejection.
Academic Article CD28-B7 costimulatory blockade by CTLA4Ig prevents actively induced experimental autoimmune encephalomyelitis and inhibits Th1 but spares Th2 cytokines in the central nervous system.
Academic Article A novel role of CD4 Th17 cells in mediating cardiac allograft rejection and vasculopathy.
Academic Article Regulatory B cells are identified by expression of TIM-1 and can be induced through TIM-1 ligation to promote tolerance in mice.
Academic Article CD4+ mononuclear cells induce cytokine expression, vascular smooth muscle cell proliferation, and arterial occlusion after endothelial injury.
Academic Article Chronic rejection in experimental cardiac transplantation in a rat model.
Academic Article The effects of nondepleting CD4 targeted therapy in presensitized rat recipients of cardiac allografts.
Academic Article Effect of targeted disruption of STAT4 and STAT6 on the induction of experimental autoimmune encephalomyelitis.
Academic Article A novel mechanism of action for anti-thymocyte globulin: induction of CD4+CD25+Foxp3+ regulatory T cells.
Academic Article Physiologic regulation of alloimmune responses in vivo: the role of CTLA4 and TH1/TH2 cytokines.
Academic Article The emerging role of T cell Ig mucin 1 in alloimmune responses in an experimental mouse transplant model.
Concept Cytokines
Academic Article CD160Ig fusion protein targets a novel costimulatory pathway and prolongs allograft survival.
Academic Article TIM4 Regulates the Anti-Islet Th2 Alloimmune Response.
Grant Costimulation and Cytokines in Tolerance
Search Criteria
  • Cytokines
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.