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One or more keywords matched the following items that are connected to Collier, R. John
Item TypeName
Academic Article Anthrax toxin-mediated delivery of a cytotoxic T-cell epitope in vivo.
Academic Article Role of macrophage oxidative burst in the action of anthrax lethal toxin.
Academic Article Characterization of membrane translocation by anthrax protective antigen.
Academic Article Mutations affecting the activity of the Shiga-like toxin I A-chain.
Academic Article Anthrax toxin entry into polarized epithelial cells.
Academic Article A quantitative study of the interactions of Bacillus anthracis edema factor and lethal factor with activated protective antigen.
Academic Article Point mutations in anthrax protective antigen that block translocation.
Academic Article Functions of phenylalanine residues within the beta-barrel stem of the anthrax toxin pore.
Academic Article 2001: a year of major advances in anthrax toxin research.
Academic Article Anthrax toxin protective antigen: low-pH-induced hydrophobicity and channel formation in liposomes.
Academic Article Combining anthrax vaccine and therapy: a dominant-negative inhibitor of anthrax toxin is also a potent and safe immunogen for vaccines.
Academic Article A soluble receptor decoy protects rats against anthrax lethal toxin challenge.
Academic Article Use of anthrax toxin fusions to stimulate immune responses.
Academic Article Exchange characteristics of calcium ions bound to anthrax protective antigen.
Academic Article Anthrax toxin: receptor binding, internalization, pore formation, and translocation.
Academic Article Inhibition of axotomy-induced neuronal apoptosis by extracellular delivery of a Bcl-XL fusion protein.
Academic Article Mapping dominant-negative mutations of anthrax protective antigen by scanning mutagenesis.
Academic Article Cytotoxic T-lymphocyte epitopes fused to anthrax toxin induce protective antiviral immunity.
Academic Article Involvement of domain 3 in oligomerization by the protective antigen moiety of anthrax toxin.
Academic Article Crystal structure of the anthrax toxin protective antigen.
Academic Article GroEL as a molecular scaffold for structural analysis of the anthrax toxin pore.
Academic Article Mapping the lethal factor and edema factor binding sites on oligomeric anthrax protective antigen.
Academic Article Exotoxin A of Pseudomonas aeruginosa: evidence that domain I functions in receptor binding.
Academic Article Whole-cell voltage clamp measurements of anthrax toxin pore current.
Academic Article Biochemical and physiological changes induced by anthrax lethal toxin in J774 macrophage-like cells.
Academic Article Use of phage display and polyvalency to design inhibitors of protein-protein interactions.
Academic Article Protein translocation through anthrax toxin channels formed in planar lipid bilayers.
Academic Article Conformational integrity of a recombinant toxoid of Pseudomonas aeruginosa exotoxin A containing a deletion of glutamic acid-553.
Academic Article Identification of residues lining the anthrax protective antigen channel.
Academic Article Characterization of dominant-negative forms of anthrax protective antigen.
Academic Article Fluorescence resonance energy transfer studies on anthrax lethal toxin.
Academic Article The structural basis for substrate and inhibitor selectivity of the anthrax lethal factor.
Academic Article Anthrax protective antigen interacts with a specific receptor on the surface of CHO-K1 cells.
Academic Article A model of anthrax toxin lethal factor bound to protective antigen.
Academic Article A loop network within the anthrax toxin pore positions the phenylalanine clamp in an active conformation.
Academic Article Mutant anthrax toxin B moiety (protective antigen) inhibits angiogenesis and tumor growth.
Academic Article Toxoid of Pseudomonas aeruginosa exotoxin A generated by deletion of an active-site residue.
Academic Article Three-dimensional structure of the anthrax toxin pore inserted into lipid nanodiscs and lipid vesicles.
Academic Article Role of CypA and Hsp90 in membrane translocation mediated by anthrax protective antigen.
Academic Article Pseudomonas aeruginosa exotoxin A: effects of mutating tyrosine-470 and tyrosine-481 to phenylalanine.
Academic Article Exotoxin A of Pseudomonas aeruginosa: substitution of glutamic acid 553 with aspartic acid drastically reduces toxicity and enzymatic activity.
Academic Article Restoration of enzymic activity and cytotoxicity of mutant, E553C, Pseudomonas aeruginosa exotoxin A by reaction with iodoacetic acid.
Academic Article Receptor-specific requirements for anthrax toxin delivery into cells.
Academic Article Structure of heptameric protective antigen bound to an anthrax toxin receptor: a role for receptor in pH-dependent pore formation.
Academic Article Phenylalanine-427 of anthrax protective antigen functions in both pore formation and protein translocation.
Academic Article Anthrax toxin: channel-forming activity of protective antigen in planar phospholipid bilayers.
Academic Article Disulfide bonds in the ectodomain of anthrax toxin receptor 2 are required for the receptor-bound protective-antigen pore to function.
Academic Article Amino acid sequence homology between the enzymic domains of diphtheria toxin and Pseudomonas aeruginosa exotoxin A.
Academic Article pH-dependent permeabilization of the plasma membrane of mammalian cells by anthrax protective antigen.
Academic Article Crystal structure of the anthrax lethal factor.
Academic Article Refined crystallographic structure of Pseudomonas aeruginosa exotoxin A and its implications for the molecular mechanism of toxicity.
Academic Article PA63 channel of anthrax toxin: an extended beta-barrel.
Academic Article Mapping the anthrax protective antigen binding site on the lethal and edema factors.
Academic Article Anthrax toxin.
Academic Article Acid-induced unfolding of the amino-terminal domains of the lethal and edema factors of anthrax toxin.
Academic Article A phenylalanine clamp catalyzes protein translocation through the anthrax toxin pore.
Academic Article Effect of 2-fluorohistidine labeling of the anthrax protective antigen on stability, pore formation, and translocation.
Academic Article Assembly of anthrax toxin pore: lethal-factor complexes into lipid nanodiscs.
Academic Article Evidence that translocation of anthrax toxin's lethal factor is initiated by entry of its N terminus into the protective antigen channel.
Academic Article Structural determinants for the binding of anthrax lethal factor to oligomeric protective antigen.
Academic Article A monoclonal antibody to Bacillus anthracis protective antigen defines a neutralizing epitope in domain 1.
Academic Article Insertion of anthrax protective antigen into liposomal membranes: effects of a receptor.
Academic Article Protective antigen-binding domain of anthrax lethal factor mediates translocation of a heterologous protein fused to its amino- or carboxy-terminus.
Academic Article Designing a polyvalent inhibitor of anthrax toxin.
Academic Article Understanding the mode of action of diphtheria toxin: a perspective on progress during the 20th century.
Academic Article The lethal and edema factors of anthrax toxin bind only to oligomeric forms of the protective antigen.
Academic Article Anthrax delivers a lethal blow to host immunity.
Academic Article Structure-activity relationships in diphtheria toxin and Pseudomonas aeruginosa exotoxin A.
Academic Article Protein translocation through the anthrax toxin transmembrane pore is driven by a proton gradient.
Academic Article Crystallization of exotoxin A from pseudomonas aeruginosa.
Academic Article The eukaryotic host factor that activates exoenzyme S of Pseudomonas aeruginosa is a member of the 14-3-3 protein family.
Academic Article Anthrax lethal toxin induces cell death-independent permeability in zebrafish vasculature.
Academic Article Cys-Cys cross-linking shows contact between the N-terminus of lethal factor and Phe427 of the anthrax toxin pore.
Academic Article Photoaffinity labeling of diphtheria toxin fragment A with NAD: structure of the photoproduct at position 148.
Academic Article Imaging the cell entry of the anthrax oedema and lethal toxins with fluorescent protein chimeras.
Academic Article Active site of Pseudomonas aeruginosa exotoxin A. Glutamic acid 553 is photolabeled by NAD and shows functional homology with glutamic acid 148 of diphtheria toxin.
Academic Article Effects of introducing a single charged residue into the phenylalanine clamp of multimeric anthrax protective antigen.
Academic Article pH-dependent perforation of macrophage phagosomes by listeriolysin O from Listeria monocytogenes.
Academic Article Exotoxin A of Pseudomonas aeruginosa: active, cloned toxin is secreted into the periplasmic space of Escherichia coli.
Academic Article Identification of the cellular receptor for anthrax toxin.
Academic Article Stoichiometry of anthrax toxin complexes.
Academic Article A dually active anthrax vaccine that confers protection against both bacilli and toxins.
Academic Article Proteolytic activation of receptor-bound anthrax protective antigen on macrophages promotes its internalization.
Academic Article Dominant-negative mutants of a toxin subunit: an approach to therapy of anthrax.
Academic Article Anthrax toxin complexes: heptameric protective antigen can bind lethal factor and edema factor simultaneously.
Academic Article Assembly and disassembly kinetics of anthrax toxin complexes.
Academic Article Anthrax toxin as a molecular tool for stimulation of cytotoxic T lymphocytes: disulfide-linked epitopes, multiple injections, and role of CD4(+) cells.
Academic Article The crystal structure of diphtheria toxin.
Academic Article Effects of eliminating a disulfide bridge within domain II of Pseudomonas aeruginosa exotoxin A.
Academic Article Antiinflammatory cAMP signaling and cell migration genes co-opted by the anthrax bacillus.
Academic Article Evidence for a proton-protein symport mechanism in the anthrax toxin channel.
Academic Article A semisynthesis platform for investigating structure-function relationships in the N-terminal domain of the anthrax Lethal Factor.
Academic Article Changing the receptor specificity of anthrax toxin.
Academic Article Structure and function of anthrax toxin.
Academic Article Chemical dissection of protein translocation through the anthrax toxin pore.
Academic Article Effects of dynamin inactivation on pathways of anthrax toxin uptake.
Academic Article Anthrax protective antigen: prepore-to-pore conversion.
Academic Article Diphtheria toxin and Pseudomonas aeruginosa exotoxin A: active-site structure and enzymic mechanism.
Academic Article Anthrax toxin receptor 2-dependent lethal toxin killing in vivo.
Academic Article Circular dichroism of diphtheria toxin, Pseudomonas aeruginosa exotoxin A, and various derivatives.
Academic Article Ultrasensitive detection of protein translocated through toxin pores in droplet-interface bilayers.
Academic Article An approach to characterizing single-subunit mutations in multimeric prepores and pores of anthrax protective antigen.
Academic Article Interactions of anthrax lethal factor with protective antigen defined by site-directed spin labeling.
Academic Article Structure of exotoxin A of Pseudomonas aeruginosa at 3.0-Angstrom resolution.
Academic Article Evidence that glutamic acid 167 is an active-site residue of Shiga-like toxin I.
Academic Article Fused polycationic peptide mediates delivery of diphtheria toxin A chain to the cytosol in the presence of anthrax protective antigen.
Academic Article Anthrax protective antigen: efficiency of translocation is independent of the number of ligands bound to the prepore.
Academic Article Anthrax toxin-mediated delivery in vivo and in vitro of a cytotoxic T-lymphocyte epitope from ovalbumin.
Academic Article Anthrax protective antigen forms oligomers during intoxication of mammalian cells.
Academic Article Effect of anthrax toxin's lethal factor on ion channels formed by the protective antigen.
Academic Article Photoaffinity labeling of active site residues in ADP-ribosylating toxins.
Academic Article On the role of macrophages in anthrax.
Academic Article Solubilization and characterization of the anthrax toxin pore in detergent micelles.
Academic Article Pseudomonas aeruginosa exotoxin A: alterations of biological and biochemical properties resulting from mutation of glutamic acid 553 to aspartic acid.
Academic Article Membrane insertion by anthrax protective antigen in cultured cells.
Academic Article Cross-linked forms of the isolated N-terminal domain of the lethal factor are potent inhibitors of anthrax toxin.
Academic Article Membrane translocation by anthrax toxin.
Concept Bacterial Toxins
Academic Article Identification of novel host-targeted compounds that protect from anthrax lethal toxin-induced cell death.
Academic Article Targeting HER2-positive cancer cells with receptor-redirected anthrax protective antigen.
Academic Article Receptor-directed chimeric toxins created by sortase-mediated protein fusion.
Academic Article Monitoring the kinetics of the pH-driven transition of the anthrax toxin prepore to the pore by biolayer interferometry and surface plasmon resonance.
Academic Article Three dimensional structure of the anthrax toxin translocon-lethal factor complex by cryo-electron microscopy.
Academic Article Polylysine-mediated translocation of the diphtheria toxin catalytic domain through the anthrax protective antigen pore.
Academic Article Atomic structure of anthrax protective antigen pore elucidates toxin translocation.
Search Criteria
  • Bacterial Toxins
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.