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One or more keywords matched the following items that are connected to Orkin, Stuart
Item TypeName
Academic Article Analysis of hemoglobin F production in Saudi Arabian families with sickle cell anemia.
Academic Article Medicine. Sickle cell disease at 100 years.
Academic Article DNA polymorphisms at the BCL11A, HBS1L-MYB, and beta-globin loci associate with fetal hemoglobin levels and pain crises in sickle cell disease.
Academic Article Saudi Arabian sickle cell anemia. A molecular approach.
Academic Article Fine-mapping at three loci known to affect fetal hemoglobin levels explains additional genetic variation.
Academic Article Hydroxyurea enhances fetal hemoglobin production in sickle cell anemia.
Academic Article Prenatal diagnosis of hemoglobinopathies.
Academic Article The switch from fetal to adult hemoglobin.
Academic Article Molecular analysis of the high-hemoglobin-F phenotype in Saudi Arabian sickle cell anemia.
Academic Article Improved detection of the sickle mutation by DNA analysis: application to prenatal diagnosis.
Academic Article Hydroxyurea increases fetal hemoglobin production in sickle cell anemia.
Academic Article Analysis of high fetal hemoglobin production in sickle cell anemia patients from the Eastern Province of Saudi Arabia.
Academic Article Correction of sickle cell disease in adult mice by interference with fetal hemoglobin silencing.
Academic Article Prenatal diagnosis of hemoglobin disorders by DNA analysis.
Academic Article High fetal hemoglobin production in sickle cell anemia in the eastern province of Saudi Arabia is genetically determined.
Academic Article Controlling the fetal globin switch in man.
Concept Anemia, Sickle Cell
Academic Article 2014 William Allan Award: A hematologist's pursuit of hemoglobin genetics.
Academic Article EHMT1 and EHMT2 inhibition induces fetal hemoglobin expression.
Academic Article Hemoglobin switching's surprise: the versatile transcription factor BCL11A is a master repressor of fetal hemoglobin.
Academic Article Transcription factors LRF and BCL11A independently repress expression of fetal hemoglobin.
Academic Article Genetic treatment of a molecular disorder: gene therapy approaches to sickle cell disease.
Academic Article MEDICINE. Paying for future success in gene therapy.
Academic Article Mathematical modeling of erythrocyte chimerism informs genetic intervention strategies for sickle cell disease.
Grant Extending GWAS at the BCL11A locus to novel therapeutics for HbF induction
Grant DEVELOPMENTAL BIOLOGY OF HUMAN ERYTHROPOIESIS
Grant CENTER FOR MOLECULAR DEVELOPMENT HEMATOPOIESIS
Grant Molecular Analysis of Normal and Thalassemic DNA
Academic Article Lineage-specific BCL11A knockdown circumvents toxicities and reverses sickle phenotype.
Academic Article Emerging Genetic Therapy for Sickle Cell Disease.
Search Criteria
  • Anemia Sickle Cell
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.