Harvard Catalyst Profiles

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One or more keywords matched the following items that are connected to Balk, Steven
Item TypeName
Academic Article Bicalutamide functions as an androgen receptor antagonist by assembly of a transcriptionally inactive receptor.
Academic Article The androgen receptor recruits nuclear receptor CoRepressor (N-CoR) in the presence of mifepristone via its N and C termini revealing a novel molecular mechanism for androgen receptor antagonists.
Academic Article AR, the cell cycle, and prostate cancer.
Academic Article Development of androgen receptor antagonists with promising activity in castration-resistant prostate cancer.
Academic Article Cyclin D1 binds the androgen receptor and regulates hormone-dependent signaling in a p300/CBP-associated factor (P/CAF)-dependent manner.
Academic Article Activation of beta-catenin signaling in prostate cancer by peptidyl-prolyl isomerase Pin1-mediated abrogation of the androgen receptor-beta-catenin interaction.
Academic Article Activity of androgen receptor antagonist bicalutamide in prostate cancer cells is independent of NCoR and SMRT corepressors.
Academic Article Increased PAK6 expression in prostate cancer and identification of PAK6 associated proteins.
Academic Article Androgen receptor mediates the expression of UDP-glucuronosyltransferase 2 B15 and B17 genes.
Academic Article In silico discovery of androgen receptor antagonists with activity in castration resistant prostate cancer.
Academic Article Structural basis for nuclear receptor corepressor recruitment by antagonist-liganded androgen receptor.
Concept Androgen Receptor Antagonists
Academic Article Androgen receptor functions in castration-resistant prostate cancer and mechanisms of resistance to new agents targeting the androgen axis.
Academic Article Targeted androgen pathway suppression in localized prostate cancer: a pilot study.
Academic Article Galeterone prevents androgen receptor binding to chromatin and enhances degradation of mutant androgen receptor.
Grant HTS for Androgen Receptor Antagonists that Recruit NCoR
Academic Article Positive feedback loop mediated by protein phosphatase 1a mobilization of P-TEFb and basal CDK1 drives androgen receptor in prostate cancer.
Academic Article Targeting the androgen receptor and overcoming resistance in prostate cancer.
Academic Article Chromatin binding of FOXA1 is promoted by LSD1-mediated demethylation in prostate cancer.
Search Criteria
  • Androgen Receptor Antagonists
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.