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One or more keywords matched the following properties of Garrett, Wendy
overview Wendy Garrett is the Irene Heinz Given Professor of Immunology and Infectious Diseases in the Departments of Immunology and Infectious Diseases and of Molecular Metabolism at the Harvard Chan School of Public Health, and also has a Professorship in the Departments of Medicine at Harvard Medical School. Dr. Garrett pursued an MD and PhD at Yale University. She completed a fellowship at the Dana-Farber Cancer Institute and postdoctoral training at Harvard University Medical School. Dr. Garrett investigates host-microbiota interactions in health and disease. Her research team studies the interplay between the gastrointestinal immune system and the gut microbiota in health, inflammatory bowel disease (IBD) and colorectal cancer (CRC). The Garrett lab focuses on how the gut microbiota influence both innate and adaptive populations and the contribution of these cells to immune homeostasis and disease. Dr. Garrett's team has identified specific species, pathways, and metabolites made by the microbiota that influence health and disease states. The lab also studies microbes and immune cells that are not only instrumental in potentiating carcinogenesis but are integral to intestinal homeostasis. The multi-faceted research approach includes meta'omics, microbiology, cellular immunology, biochemistry, cell biology, and cancer biology. The lab uses mouse models, human specimens, and primary and transformed mammalian cells and bacterial cells in their experiments in order to move facilely between large human data sets and in vivo and in vitro model systems with a core mission of determining basic biologic mechanism and applying the findings to precision medicine. The Garrett lab is highly collaborative and works with many laboratories at institutions in the greater Boston area, in Harvard-affiliated hospitals and institutes, and at national and international research centers.
One or more keywords matched the following items that are connected to Garrett, Wendy
Item TypeName
Academic Article Metagenomic biomarker discovery and explanation.
Academic Article A complex microworld in the gut: gut microbiota and cardiovascular disease connectivity.
Academic Article Host and gut microbiota symbiotic factors: lessons from inflammatory bowel disease and successful symbionts.
Academic Article Enterobacteriaceae act in concert with the gut microbiota to induce spontaneous and maternally transmitted colitis.
Academic Article The gut microbiota and mucosal T cells.
Academic Article Genomic analysis identifies association of Fusobacterium with colorectal carcinoma.
Academic Article Current concepts of the intestinal microbiota and the pathogenesis of infection.
Concept Metagenome
Academic Article Computational meta'omics for microbial community studies.
Academic Article The microbial metabolites, short-chain fatty acids, regulate colonic Treg cell homeostasis.
Academic Article Exploring host-microbiota interactions in animal models and humans.
Academic Article Kwashiorkor and the gut microbiota.
Academic Article Gut microbiome composition and function in experimental colitis during active disease and treatment-induced remission.
Academic Article Microbes and inflammation in colorectal cancer.
Academic Article Microbes, microbiota, and colon cancer.
Academic Article Relating the metatranscriptome and metagenome of the human gut.
Academic Article Functional profiling of the gut microbiome in disease-associated inflammation.
Academic Article Cancer and the microbiota.
Academic Article Nutrients, foods, and colorectal cancer prevention.
Academic Article Gut microbiota. Microbiota organization--a key to understanding CRC development.
Academic Article Host microbiota constantly control maturation and function of microglia in the CNS.
Academic Article From cell biology to the microbiome: An intentional infinite loop.
Academic Article Tuft cells, taste-chemosensory cells, orchestrate parasite type 2 immunity in the gut.
Academic Article The reproductive tracts of two malaria vectors are populated by a core microbiome and by gender- and swarm-enriched microbial biomarkers.
Academic Article Gut microbiota, metabolites and host immunity.
Academic Article Ecological robustness of the gut microbiota in response to ingestion of transient food-borne microbes.
Grant Dietary sulfur, the gut microbiome, and colorectal cancer
Grant Disease Initation and the role of DCs in the TRUC Model of ulcerative colitis
Grant The gut microbiota and ethanol
Grant Colorectal carcinogenesis and Fusobacterium nucleatum: oncomicrobe, oncometabolites, and oncoimmunology
Academic Article Gut Microbiota, Inflammation, and Colorectal Cancer.
Grant Designer Probiotics for the treatment of intestinal infection and inflammation
Academic Article Gut microbiota induce IGF-1 and promote bone formation and growth.
Academic Article QseC inhibition as an antivirulence approach for colitis-associated bacteria.
Academic Article Gut microbiota in 2016: A banner year for gut microbiota research.
Academic Article Association of Dietary Patterns With Risk of Colorectal Cancer Subtypes Classified by Fusobacterium nucleatum in Tumor Tissue.
Academic Article Fighting Fire with Fiber: Preventing T Cell Infiltration in Diabetes.
Academic Article The Unfolding Story of ATF6, Microbial Dysbiosis, and Colorectal Cancer.
Academic Article The Crohn's disease polymorphism, ATG16L1 T300A, alters the gut microbiota and enhances the local Th1/Th17 response.
Academic Article The human gut bacterial genotoxin colibactin alkylates DNA.
Academic Article The cancer microbiome.
Academic Article The gut microbiota and colon cancer.
Academic Article Metabolite-Sensing Receptor Ffar2 Regulates Colonic Group 3 Innate Lymphoid Cells and Gut Immunity.
Academic Article Immune recognition of microbial metabolites.
Academic Article Expression of Free Fatty Acid Receptor 2 by Dendritic Cells Prevents Their Expression of Interleukin 27 and Is Required for Maintenance of Mucosal Barrier and Immune Response Against Colorectal Tumors in Mice.
Academic Article Association Between Sulfur-Metabolizing Bacterial Communities in Stool and Risk of Distal Colorectal Cancer in Men.
Academic Article The Taste Receptor TAS1R3 Regulates Small Intestinal Tuft Cell Homeostasis.
Academic Article Enterococcus in Graft-versus-Host Disease.
Academic Article Structure of the Mucosal and Stool Microbiome in Lynch Syndrome.
Grant Prebiotic effect of eicosapentaenoic acid treatment for colorectal cancer
Academic Article Diet posttranslationally modifies the mouse gut microbial proteome to modulate renal function.
Academic Article Microbial Nourishment for Undernutrition.
Academic Article A framework for microbiome science in public health.
Academic Article Overview of the Microbiome Among Nurses study (Micro-N) as an example of prospective characterization of the microbiome within cohort studies.
Academic Article Publisher Correction: Overview of the Microbiome Among Nurses study (Micro-N) as an example of prospective characterization of the microbiome within cohort studies.
Academic Article Dietary fiber intake, the gut microbiome, and chronic systemic inflammation in a cohort of adult men.
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  • Microbiota
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.