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One or more keywords matched the following items that are connected to Mitchison, Timothy
Item TypeName
Academic Article An inner centromere protein that stimulates the microtubule depolymerizing activity of a KinI kinesin.
Academic Article Evidence for kinesin-related proteins in the mitotic apparatus using peptide antibodies.
Academic Article Dissecting temporal and spatial control of cytokinesis with a myosin II Inhibitor.
Academic Article Poly(ADP-ribose) is required for spindle assembly and structure.
Academic Article Allele-specific activators and inhibitors for kinesin.
Academic Article Roles of polymerization dynamics, opposed motors, and a tensile element in governing the length of Xenopus extract meiotic spindles.
Academic Article A model for the proposed roles of different microtubule-based motor proteins in establishing spindle bipolarity.
Academic Article Evidence that monastrol is an allosteric inhibitor of the mitotic kinesin Eg5.
Academic Article The bipolar kinesin, KLP61F, cross-links microtubules within interpolar microtubule bundles of Drosophila embryonic mitotic spindles.
Academic Article Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen.
Academic Article XCTK2: a kinesin-related protein that promotes mitotic spindle assembly in Xenopus laevis egg extracts.
Academic Article Eg5 causes elongation of meiotic spindles when flux-associated microtubule depolymerization is blocked.
Academic Article Cell biology. Motoring in the spindle.
Academic Article Different axoplasmic proteins generate movement in opposite directions along microtubules in vitro.
Academic Article Purification of cytoskeletal proteins using peptide antibodies.
Academic Article Kin I kinesins are microtubule-destabilizing enzymes.
Academic Article Eg5 is static in bipolar spindles relative to tubulin: evidence for a static spindle matrix.
Academic Article Microtubule plus-end dynamics in Xenopus egg extract spindles.
Academic Article Nonredundant functions of Kinesin-13s during meiotic spindle assembly.
Academic Article A standardized kinesin nomenclature.
Academic Article Mechanism and function of poleward flux in Xenopus extract meiotic spindles.
Academic Article Slide-and-cluster models for spindle assembly.
Academic Article Prolonged mitotic arrest triggers partial activation of apoptosis, resulting in DNA damage and p53 induction.
Academic Article Kinesin-related proteins at mitotic spindle poles: function and regulation.
Academic Article Quantitative live imaging of cancer and normal cells treated with Kinesin-5 inhibitors indicates significant differences in phenotypic responses and cell fate.
Academic Article Mutations in the kinesin-like protein Eg5 disrupting localization to the mitotic spindle.
Academic Article Spindle fusion requires dynein-mediated sliding of oppositely oriented microtubules.
Academic Article The role of microtubule polarity in the movement of kinesin and kinetochores.
Academic Article The microtubule-destabilizing kinesin XKCM1 is required for chromosome positioning during spindle assembly.
Academic Article Probing spindle assembly mechanisms with monastrol, a small molecule inhibitor of the mitotic kinesin, Eg5.
Academic Article Evidence that mitotic exit is a better cancer therapeutic target than spindle assembly.
Academic Article A novel small-molecule inhibitor reveals a possible role of kinesin-5 in anastral spindle-pole assembly.
Academic Article Rapid induction of apoptosis during Kinesin-5 inhibitor-induced mitotic arrest in HL60 cells.
Academic Article The kinesin Eg5 drives poleward microtubule flux in Xenopus laevis egg extract spindles.
Academic Article Cell type variation in responses to antimitotic drugs that target microtubules and kinesin-5.
Academic Article XKCM1: a Xenopus kinesin-related protein that regulates microtubule dynamics during mitotic spindle assembly.
Academic Article Functional overlap of microtubule assembly factors in chromatin-promoted spindle assembly.
Academic Article Identification and partial characterization of mitotic centromere-associated kinesin, a kinesin-related protein that associates with centromeres during mitosis.
Academic Article An intermittent live cell imaging screen for siRNA enhancers and suppressors of a kinesin-5 inhibitor.
Academic Article KIF4 regulates midzone length during cytokinesis.
Academic Article Microtubule flux in mitosis is independent of chromosomes, centrosomes, and antiparallel microtubules.
Academic Article Differentiation of cytoplasmic and meiotic spindle assembly MCAK functions by Aurora B-dependent phosphorylation.
Concept Kinesin
Academic Article Cell motility: good things from slime.
Academic Article Midbody assembly and its regulation during cytokinesis.
Academic Article FRET measurements of kinesin neck orientation reveal a structural basis for processivity and asymmetry.
Academic Article Self-organization of stabilized microtubules by both spindle and midzone mechanisms in Xenopus egg cytosol.
Academic Article Spatial organization of cytokinesis signaling reconstituted in a cell-free system.
Academic Article Identification of MAC1: A Small Molecule That Rescues Spindle Bipolarity in Monastrol-Treated Cells.
Academic Article Increased lateral microtubule contact at the cell cortex is sufficient to drive mammalian spindle elongation.
Academic Article Prc1E and Kif4A control microtubule organization within and between large Xenopus egg asters.
Academic Article Spatial variation of microtubule depolymerization in large asters.
Search Criteria
  • Kinesin
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.