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Low prevalence of germline CDKN2A and CDK4 mutations in patients with early-onset melanoma.
Genetic testing in hereditary melanoma.
Novel mutations in the p16/CDKN2A binding region of the cyclin-dependent kinase-4 gene.
Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 7-2004. A 48-year-old woman with multiple pigmented lesions and a personal and family history of melanoma.
American Academy of Dermatology 1999 Awards for Young Investigators in Dermatology. Targets of genetic injury in cutaneous melanoma.
A two-stage, p16(INK4A)- and p53-dependent keratinocyte senescence mechanism that limits replicative potential independent of telomere status.
Germline CDKN2A mutations among Greek patients with early-onset and multiple primary cutaneous melanoma.
Features associated with germline CDKN2A mutations: a GenoMEL study of melanoma-prone families from three continents.
The M53I mutation in CDKN2A is a founder mutation that predominates in melanoma patients with Scottish ancestry.
Comprehensive field synopsis and systematic meta-analyses of genetic association studies in cutaneous melanoma.
Genetics of melanoma predisposition.
A novel methionine-53-valine mutation of p16 in a hereditary melanoma kindred.
Recurrent patterns of dual RB and p53 pathway inactivation in melanoma.
Loss of xeroderma pigmentosum C (Xpc) enhances melanoma photocarcinogenesis in Ink4a-Arf-deficient mice.
Melanoma prone families with CDK4 germline mutation: phenotypic profile and associations with MC1R variants.
A flexible multiplex bead-based assay for detecting germline CDKN2A and CDK4 variants in melanoma-prone kindreds.
Cyclin-Dependent Kinase 6
Cyclin-Dependent Kinase Inhibitor p16
Cyclin-Dependent Kinase 4
Cyclin-Dependent Kinase Inhibitor p18
Targeted Therapies in Melanoma: Translational Research at Its Finest.
A Symmetric Eczematous Eruption Harboring Thousands of Melanocytic Lesions.
Reply to: "The absence of multiple atypical nevi in germline CDKN2A mutations".
CDKN2A/CDK4 Status in Greek Patients with Familial Melanoma and Association with Clinico-epidemiological Parameters.
Cyclin Dependent Kinase 3