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Item TypeName
Academic Article Identification of target antigens for the human cytotoxic T cell response to Epstein-Barr virus (EBV): implications for the immune control of EBV-positive malignancies.
Academic Article Expression of Epstein-Barr virus nuclear antigens in anti-IgM-stimulated B cells following recombinant vaccinia infection and their recognition by human cytotoxic T cells.
Academic Article Epstein-Barr virus (EBV)-negative B-lymphoma cell lines for clonal isolation and replication of EBV recombinants.
Academic Article Epstein-Barr virus nuclear antigen 1 activates transcription from episomal but not integrated DNA and does not alter lymphocyte growth.
Academic Article Epstein-Barr virus nuclear protein 2 transactivates a cis-acting CD23 DNA element.
Academic Article EBNA3C coactivation with EBNA2 requires a SUMO homology domain.
Academic Article The Epstein-Barr virus nuclear protein encoded by the leader of the EBNA RNAs is important in B-lymphocyte transformation.
Academic Article Maintenance of Epstein-Barr virus (EBV) oriP-based episomes requires EBV-encoded nuclear antigen-1 chromosome-binding domains, which can be replaced by high-mobility group-I or histone H1.
Academic Article Epstein-Barr virus exploits intrinsic B-lymphocyte transcription programs to achieve immortal cell growth.
Academic Article EBNA3A association with RBP-Jkappa down-regulates c-myc and Epstein-Barr virus-transformed lymphoblast growth.
Academic Article Protein kinase A associates with HA95 and affects transcriptional coactivation by Epstein-Barr virus nuclear proteins.
Academic Article Four EBNA2 domains are important for EBNALP coactivation.
Academic Article Second-site homologous recombination in Epstein-Barr virus: insertion of type 1 EBNA 3 genes in place of type 2 has no effect on in vitro infection.
Academic Article Epstein-Barr virus nuclear protein 2 interacts with p300, CBP, and PCAF histone acetyltransferases in activation of the LMP1 promoter.
Academic Article Restricted Epstein-Barr virus protein expression in Burkitt lymphoma is due to a different Epstein-Barr nuclear antigen 1 transcriptional initiation site.
Academic Article Epstein-Barr Virus nuclear protein EBNA3A is critical for maintaining lymphoblastoid cell line growth.
Academic Article Use of second-site homologous recombination to demonstrate that Epstein-Barr virus nuclear protein 3B is not important for lymphocyte infection or growth transformation in vitro.
Academic Article Induction of germ-line and mature C epsilon transcripts in human B cells stimulated with rIL-4 and EBV.
Academic Article Modulation of Epstein-Barr virus nuclear antigen 2-dependent transcription by protein arginine methyltransferase 5.
Academic Article Epstein-Barr virus latent membrane protein (LMP1) and nuclear proteins 2 and 3C are effectors of phenotypic changes in B lymphocytes: EBNA-2 and LMP1 cooperatively induce CD23.
Academic Article A third viral nuclear protein in lymphoblasts immortalized by Epstein-Barr virus.
Academic Article The residues between the two transformation effector sites of Epstein-Barr virus latent membrane protein 1 are not critical for B-lymphocyte growth transformation.
Academic Article Altered growth phenotype of a Burkitt's lymphoma line following the introduction and stable expression of the EBNA 2A gene.
Academic Article A sixth Epstein-Barr virus nuclear protein (EBNA3B) is expressed in latently infected growth-transformed lymphocytes.
Academic Article Identification and characterization of a cellular protein that cross-reacts with the Epstein-Barr virus nuclear antigen.
Academic Article An Epstein-Barr virus with a 58-kilobase-pair deletion that includes BARF0 transforms B lymphocytes in vitro.
Academic Article Pim kinases are upregulated during Epstein-Barr virus infection and enhance EBNA2 activity.
Academic Article Epstein-Barr virus nuclear antigen 3C regulated genes in lymphoblastoid cell lines.
Academic Article The 62- and 80-kDa subunits of transcription factor IIH mediate the interaction with Epstein-Barr virus nuclear protein 2.
Academic Article Epstein-Barr virus nuclear antigen 1 does not induce lymphoma in transgenic FVB mice.
Academic Article Epstein-Barr virus BHRF1 micro- and stable RNAs during latency III and after induction of replication.
Academic Article Epstein-Barr virus vectors for gene delivery to B lymphocytes.
Academic Article Genetic and biochemical evidence that EBNA 2 interaction with a 63-kDa cellular GTG-binding protein is essential for B lymphocyte growth transformation by EBV.
Academic Article The amino-terminal domains of Epstein-Barr virus nuclear proteins 3A, 3B, and 3C interact with RBPJ(kappa).
Academic Article Epstein-Barr virus nuclear antigen 2 transactivates latent membrane protein LMP1.
Academic Article EBV nuclear antigen EBNALP dismisses transcription repressors NCoR and RBPJ from enhancers and EBNA2 increases NCoR-deficient RBPJ DNA binding.
Academic Article Nucleotide sequences of mRNAs encoding Epstein-Barr virus nuclear proteins: a probable transcriptional initiation site.
Academic Article The Epstein-Barr virus nuclear antigen 2 transactivator is directed to response elements by the J kappa recombination signal binding protein.
Academic Article Epstein-Barr virus nuclear proteins EBNA-3A and EBNA-3C are essential for B-lymphocyte growth transformation.
Academic Article Epstein-Barr virus (EBV) antigen-specific leukocyte migration inhibition (LMI) in infectious mononucleosis (IM). I. Kinetics and response to a membrane protein on EBV-transformed cells.
Academic Article Expression of the Epstein-Barr virus nuclear protein 2 in rodent cells.
Academic Article Epstein-Barr virus nuclear protein 3C modulates transcription through interaction with the sequence-specific DNA-binding protein J kappa.
Academic Article Epstein-Barr virus nuclear protein 3C binds to the N-terminal (NTD) and beta trefoil domains (BTD) of RBP/CSL; only the NTD interaction is essential for lymphoblastoid cell growth.
Academic Article A fifth Epstein-Barr virus nuclear protein (EBNA3C) is expressed in latently infected growth-transformed lymphocytes.
Academic Article Expression of epstein-barr virus nuclear antigen 1 is associated with enhanced expression of CD25 in the Hodgkin cell line L428.
Academic Article The Epstein-Barr virus nuclear protein 2 acidic domain forms a complex with a novel cellular coactivator that can interact with TFIIE.
Academic Article The Epstein-Barr virus (EBV) nuclear antigen 1 BamHI F promoter is activated on entry of EBV-transformed B cells into the lytic cycle.
Academic Article Delineation of the cis-acting element mediating EBNA-2 transactivation of latent infection membrane protein expression.
Academic Article One of two Epstein-Barr virus nuclear antigens contains a glycine-alanine copolymer domain.
Academic Article Epstein-Barr virus nuclear protein LP stimulates EBNA-2 acidic domain-mediated transcriptional activation.
Academic Article EBNA-3B- and EBNA-3C-regulated cellular genes in Epstein-Barr virus-immortalized lymphoblastoid cell lines.
Academic Article Distinction between Epstein-Barr virus type A (EBNA 2A) and type B (EBNA 2B) isolates extends to the EBNA 3 family of nuclear proteins.
Academic Article Early events in Epstein-Barr virus infection of human B lymphocytes.
Academic Article Expression of Epstein-Barr virus transformation-associated genes in tissues of patients with EBV lymphoproliferative disease.
Academic Article Epstein-Barr virus nuclear protein 2 is a key determinant of lymphocyte transformation.
Academic Article Repeat arrays in cellular DNA related to the Epstein-Barr virus IR3 repeat.
Academic Article EBNA-2 and EBNA-3C extensively and mutually exclusively associate with RBPJkappa in Epstein-Barr virus-transformed B lymphocytes.
Academic Article A second nuclear protein is encoded by Epstein-Barr virus in latent infection.
Academic Article Direct interactions between Epstein-Barr virus leader protein LP and the EBNA2 acidic domain underlie coordinate transcriptional regulation.
Academic Article Epstein-Barr virus (EBV) recombinants: use of positive selection markers to rescue mutants in EBV-negative B-lymphoma cells.
Academic Article Mediation of Epstein-Barr virus EBNA-LP transcriptional coactivation by Sp100.
Academic Article RNAs induced by Epstein-Barr virus nuclear antigen 2 in lymphoblastoid cell lines.
Academic Article Epstein-Barr nuclear antigen leader protein coactivates transcription through interaction with histone deacetylase 4.
Academic Article Subnuclear localization and phosphorylation of Epstein-Barr virus latent infection nuclear proteins.
Academic Article Epstein-Barr virus nuclear antigen 1 does not cause lymphoma in C57BL/6J mice.
Academic Article An Epstein-Barr virus nuclear protein 2 domain essential for transformation is a direct transcriptional activator.
Academic Article Small molecule and peptide-mediated inhibition of Epstein-Barr virus nuclear antigen 1 dimerization.
Academic Article Herpes simplex virus expressing Epstein-Barr virus nuclear antigen 1.
Academic Article The biology and chemistry of Epstein-Barr virus.
Academic Article Epstein-Barr virus nuclear protein EBNA3C residues critical for maintaining lymphoblastoid cell growth.
Academic Article The EBNA-2 arginine-glycine domain is critical but not essential for B-lymphocyte growth transformation; the rest of region 3 lacks essential interactive domains.
Academic Article Epstein-Barr virus nuclear protein 3C domains necessary for lymphoblastoid cell growth: interaction with RBP-Jkappa regulates TCL1.
Academic Article Epstein-Barr virus nuclear protein 2 transactivation of the latent membrane protein 1 promoter is mediated by J kappa and PU.1.
Academic Article Epstein-Barr virus recombinants from overlapping cosmid fragments.
Academic Article Roscovitine inhibits EBNA1 serine 393 phosphorylation, nuclear localization, transcription, and episome maintenance.
Academic Article Epstein-Barr virus-specific cytotoxic T-cell recognition of transfectants expressing the virus-coded latent membrane protein LMP.
Academic Article Epstein-Barr virus nuclear antigen 2 specifically induces expression of the B-cell activation antigen CD23.
Academic Article U2 region of Epstein-Barr virus DNA may encode Epstein-Barr nuclear antigen 2.
Academic Article Epstein-Barr virus nuclear protein 3A domains essential for growth of lymphoblasts: transcriptional regulation through RBP-Jkappa/CBF1 is critical.
Academic Article Human cytotoxic T-cell responses against Epstein-Barr virus nuclear antigens demonstrated by using recombinant vaccinia viruses.
Academic Article Epstein-Barr virus types 1 and 2 differ in their EBNA-3A, EBNA-3B, and EBNA-3C genes.
Academic Article Simple repeat array in Epstein-Barr virus DNA encodes part of the Epstein-Barr nuclear antigen.
Academic Article The N-terminal half of EBNA2, except for seven prolines, is not essential for primary B-lymphocyte growth transformation.
Academic Article The nuclear chaperone nucleophosmin escorts an Epstein-Barr Virus nuclear antigen to establish transcriptional cascades for latent infection in human B cells.
Academic Article The Epstein-Barr virus nuclear protein 2 acidic domain can interact with TFIIB, TAF40, and RPA70 but not with TATA-binding protein.
Academic Article The Epstein-Barr virus nuclear antigen leader protein associates with hsp72/hsc73.
Academic Article Recognition of the Epstein-Barr virus-encoded nuclear antigens EBNA-4 and EBNA-6 by HLA-A11-restricted cytotoxic T lymphocytes: implications for down-regulation of HLA-A11 in Burkitt lymphoma.
Academic Article Localization of Epstein-Barr virus cytotoxic T cell epitopes using recombinant vaccinia: implications for vaccine development.
Academic Article Residues 231 to 280 of the Epstein-Barr virus nuclear protein 2 are not essential for primary B-lymphocyte growth transformation.
Academic Article Intracellular forms of human NOTCH1 interact at distinctly different levels with RBP-jkappa in human B and T cells.
Academic Article Epstein-Barr virus nuclear antigen 3C putative repression domain mediates coactivation of the LMP1 promoter with EBNA-2.
Academic Article Epstein-Barr virus nuclear protein 2 mutations define essential domains for transformation and transactivation.
Academic Article Hsp72 up-regulates Epstein-Barr virus EBNALP coactivation with EBNA2.
Academic Article Epstein-Barr virus nuclear antigens 3C and 3A maintain lymphoblastoid cell growth by repressing p16INK4A and p14ARF expression.
Academic Article Definitive identification of a member of the Epstein-Barr virus nuclear protein 3 family.
Academic Article Reducing the complexity of the transforming Epstein-Barr virus genome to 64 kilobase pairs.
Concept Epstein-Barr Virus Nuclear Antigens
Academic Article Epstein-Barr virus nuclear antigen leader protein localizes to promoters and enhancers with cell transcription factors and EBNA2.
Academic Article Nucleolin is important for Epstein-Barr virus nuclear antigen 1-mediated episome binding, maintenance, and transcription.
Academic Article Epstein-Barr virus nuclear antigen 3C binds to BATF/IRF4 or SPI1/IRF4 composite sites and recruits Sin3A to repress CDKN2A.
Academic Article Small molecule inhibition of Epstein-Barr virus nuclear antigen-1 DNA binding activity interferes with replication and persistence of the viral genome.
Academic Article Epstein-Barr virus nuclear antigen 3A partially coincides with EBNA3C genome-wide and is tethered to DNA through BATF complexes.
Academic Article Epstein-Barr virus latent genes.
Academic Article Ribosome Protein L4 is essential for Epstein-Barr Virus Nuclear Antigen 1 function.
Grant Epstein-Barr Virus Nuclear Protein B Cell Growth Transformation
Grant Roles of Epstein-Barr virus nuclear antigens 2 and LP in B cell proliferation
Academic Article The Epstein-Barr Virus Regulome in Lymphoblastoid Cells.
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  • Epstein Barr Virus Nuclear Antigens
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.