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One or more keywords matched the following items that are connected to Chasman, Dan
Item TypeName
Academic Article Population-based genomewide genetic analysis of common clinical chemistry analytes.
Academic Article New loci associated with kidney function and chronic kidney disease.
Academic Article Genetic variants in eleven telomere-associated genes and the risk of incident cardio/cerebrovascular disease: The Women's Genome Health Study.
Academic Article Loci related to metabolic-syndrome pathways including LEPR,HNF1A, IL6R, and GCKR associate with plasma C-reactive protein: the Women's Genome Health Study.
Academic Article Predicting the functional consequences of non-synonymous single nucleotide polymorphisms: structure-based assessment of amino acid variation.
Academic Article Rationale, design, and methodology of the Women's Genome Health Study: a genome-wide association study of more than 25,000 initially healthy american women.
Academic Article Multiple loci associated with indices of renal function and chronic kidney disease.
Academic Article Mitochondrial uncoupling protein gene cluster variation (UCP2-UCP3) and the risk of incident type 2 diabetes mellitus: the Women's Genome Health Study.
Academic Article Biological, clinical and population relevance of 95 loci for blood lipids.
Academic Article Genetic determinants of statin-induced low-density lipoprotein cholesterol reduction: the Justification for the Use of Statins in Prevention: an Intervention Trial Evaluating Rosuvastatin (JUPITER) trial.
Academic Article Genome-wide association studies identify loci associated with age at menarche and age at natural menopause.
Academic Article Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function.
Academic Article Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy.
Academic Article Loci influencing blood pressure identified using a cardiovascular gene-centric array.
Academic Article Genetic determinants of cardiovascular events among women with migraine: a genome-wide association study.
Academic Article Genome-wide meta-analysis identifies regions on 7p21 (AHR) and 15q24 (CYP1A2) as determinants of habitual caffeine consumption.
Academic Article Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure.
Academic Article Meta-analysis identifies six new susceptibility loci for atrial fibrillation.
Academic Article Tracing sub-structure in the European American population with PCA-informative markers.
Academic Article Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies.
Academic Article Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.
Academic Article Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.
Academic Article A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6q14 and 20q11.
Academic Article Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture.
Academic Article Genetic variation of fifteen folate metabolic pathway associated gene loci and the risk of incident head and neck carcinoma: the Women's Genome Health Study.
Academic Article Genome-wide association study of relative telomere length.
Academic Article Genome-wide association study identifies variants at the IL18-BCO2 locus associated with interleukin-18 levels.
Academic Article Large-scale candidate gene analysis of HDL particle features.
Academic Article Genetic variants of 11 telomere-pathway gene loci and the risk of incident type 2 diabetes mellitus: the Women's Genome Health Study.
Academic Article Novel associations of CPS1, MUT, NOX4, and DPEP1 with plasma homocysteine in a healthy population: a genome-wide evaluation of 13 974 participants in the Women's Genome Health Study.
Academic Article FTO genotype is associated with phenotypic variability of body mass index.
Academic Article Genome-wide association studies identify four ER negative-specific breast cancer risk loci.
Academic Article Genome-wide association of lipid-lowering response to statins in combined study populations.
Academic Article Genome-wide association study reveals three susceptibility loci for common migraine in the general population.
Academic Article Novel association of HK1 with glycated hemoglobin in a non-diabetic population: a genome-wide evaluation of 14,618 participants in the Women's Genome Health Study.
Academic Article Novel loci, including those related to Crohn disease, psoriasis, and inflammation, identified in a genome-wide association study of fibrinogen in 17 686 women: the Women's Genome Health Study.
Academic Article Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors.
Academic Article Islet amyloid polypeptide gene variation (IAPP) and the risk of incident type 2 diabetes mellitus: the Women's Genome Health Study.
Academic Article Population analysis of large copy number variants and hotspots of human genetic disease.
Academic Article Polymorphism in the CETP gene region, HDL cholesterol, and risk of future myocardial infarction: Genomewide analysis among 18 245 initially healthy women from the Women's Genome Health Study.
Academic Article Genetic variants at 2q24 are associated with susceptibility to type 2 diabetes.
Academic Article Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.
Academic Article Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.
Academic Article Genome-wide association analysis of soluble ICAM-1 concentration reveals novel associations at the NFKBIK, PNPLA3, RELA, and SH2B3 loci.
Academic Article Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.
Academic Article Discovery and replication of novel blood pressure genetic loci in the Women's Genome Health Study.
Academic Article Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study.
Academic Article A common variant at the TERT-CLPTM1L locus is associated with estrogen receptor-negative breast cancer.
Academic Article A genome-wide analysis of 'Bounty' descendants implicates several novel variants in migraine susceptibility.
Academic Article Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.
Academic Article Genome-wide association and functional follow-up reveals new loci for kidney function.
Academic Article On the utility of gene set methods in genomewide association studies of quantitative traits.
Academic Article A genome-wide association study of early menopause and the combined impact of identified variants.
Academic Article Novel association of ABO histo-blood group antigen with soluble ICAM-1: results of a genome-wide association study of 6,578 women.
Academic Article Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.
Academic Article Pharmacogenetic determinants of statin-induced reductions in C-reactive protein.
Academic Article Genome-wide linkage and association analyses implicate FASN in predisposition to Uterine Leiomyomata.
Academic Article Genetic loci associated with plasma concentration of low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, triglycerides, apolipoprotein A1, and Apolipoprotein B among 6382 white women in genome-wide analysis with replication.
Academic Article Hundreds of variants clustered in genomic loci and biological pathways affect human height.
Academic Article Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.
Academic Article Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways.
Academic Article On the use of variance per genotype as a tool to identify quantitative trait interaction effects: a report from the Women's Genome Health Study.
Academic Article Novel locus including FGF21 is associated with dietary macronutrient intake.
Concept Genome-Wide Association Study
Concept Genome
Concept Genome, Human
Academic Article Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits.
Academic Article Genome-wide meta-analysis identifies new susceptibility loci for migraine.
Academic Article A genome-wide association study for venous thromboembolism: the extended cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium.
Academic Article Genome-wide meta-analysis of observational studies shows common genetic variants associated with macronutrient intake.
Academic Article Discovery and refinement of loci associated with lipid levels.
Academic Article Currently available versions of genome-wide association studies cannot be used to query the common haptoglobin copy number variant.
Academic Article Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease.
Academic Article Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations.
Academic Article Common variants in Mendelian kidney disease genes and their association with renal function.
Academic Article Gene variations of ROCKs and risk of ischaemic stroke: the Women's Genome Health Study.
Academic Article DNA mismatch repair gene MSH6 implicated in determining age at natural menopause.
Academic Article Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci.
Academic Article Genetics, ancestry, and hypertension: implications for targeted antihypertensive therapies.
Academic Article Plasma levels of the proinflammatory chitin-binding glycoprotein YKL-40, variation in the chitinase 3-like 1 gene (CHI3L1), and incident cardiovascular events.
Academic Article Effects of long-term averaging of quantitative blood pressure traits on the detection of genetic associations.
Academic Article Pleiotropic genes for metabolic syndrome and inflammation.
Academic Article Polymorphisms in catechol-O-methyltransferase modify treatment effects of aspirin on risk of cardiovascular disease.
Academic Article Defining the role of common variation in the genomic and biological architecture of adult human height.
Academic Article Common genetic variations in the vitamin D pathway in relation to blood pressure.
Academic Article Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.
Academic Article Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins.
Academic Article Genome-wide association study of kidney function decline in individuals of European descent.
Academic Article Genetic loci associated with circulating levels of very long-chain saturated fatty acids.
Academic Article Association of exome sequences with plasma C-reactive protein levels in >9000 participants.
Academic Article No evidence for genome-wide interactions on plasma fibrinogen by smoking, alcohol consumption and body mass index: results from meta-analyses of 80,607 subjects.
Academic Article New genetic loci link adipose and insulin biology to body fat distribution.
Academic Article Genetic studies of body mass index yield new insights for obesity biology.
Academic Article A multivariate genome-wide association analysis of 10 LDL subfractions, and their response to statin treatment, in 1868 Caucasians.
Academic Article Vitamin D-associated genetic variation and risk of breast cancer in the breast and prostate cancer cohort consortium (BPC3).
Academic Article Efficient Bayesian mixed-model analysis increases association power in large cohorts.
Academic Article Shared genetic basis for migraine and ischemic stroke: A genome-wide analysis of common variants.
Academic Article Genetic loci associated with circulating phospholipid trans fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.
Academic Article Genome-wide association study of selenium concentrations.
Academic Article Is the adiposity-associated FTO gene variant related to all-cause mortality independent of adiposity? Meta-analysis of data from 169,551 Caucasian adults.
Academic Article Polygenic Overlap Between C-Reactive Protein, Plasma Lipids, and Alzheimer Disease.
Academic Article Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium.
Academic Article Understanding multicellular function and disease with human tissue-specific networks.
Academic Article Meta-analysis of 65,734 individuals identifies TSPAN15 and SLC44A2 as two susceptibility loci for venous thromboembolism.
Academic Article Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption.
Academic Article Pleiotropy among common genetic loci identified for cardiometabolic disorders and C-reactive protein.
Academic Article Directional dominance on stature and cognition in diverse human populations.
Academic Article The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.
Academic Article Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores.
Academic Article Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture.
Academic Article A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease.
Academic Article Population genetic differentiation of height and body mass index across Europe.
Academic Article Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair.
Academic Article Genome-wide association analysis identifies TXNRD2, ATXN2 and FOXC1 as susceptibility loci for primary open-angle glaucoma.
Academic Article A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration.
Academic Article GWAS for executive function and processing speed suggests involvement of the CADM2 gene.
Academic Article Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function.
Academic Article Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels.
Academic Article Genome-Wide Association Study for Incident Myocardial Infarction and Coronary Heart Disease in Prospective Cohort Studies: The CHARGE Consortium.
Academic Article Identifying Novel Gene Variants in Coronary Artery Disease and Shared Genes With Several Cardiovascular Risk Factors.
Academic Article Gene co-expression analysis identifies brain regions and cell types involved in migraine pathophysiology: a GWAS-based study using the Allen Human Brain Atlas.
Academic Article Physical and neurobehavioral determinants of reproductive onset and success.
Academic Article Gene-based pleiotropy across migraine with aura and migraine without aura patient groups.
Academic Article An Empirical Comparison of Joint and Stratified Frameworks for Studying G × E Interactions: Systolic Blood Pressure and Smoking in the CHARGE Gene-Lifestyle Interactions Working Group.
Academic Article Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine.
Academic Article Four Susceptibility Loci for Gallstone Disease Identified in a Meta-analysis of Genome-Wide Association Studies.
Academic Article Migraine genetics: from genome-wide association studies to translational insights.
Grant Genetic contribution to sub-classified migraine in the adult population
Academic Article Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci.
Academic Article The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals.
Academic Article Is there still room for additional common susceptibility alleles for venous thromboembolism?
Academic Article Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.
Academic Article Gene-gene Interaction Analyses for Atrial Fibrillation.
Academic Article A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape.
Academic Article Genome-wide analysis identifies 12 loci influencing human reproductive behavior.
Academic Article Meta-analysis of genome-wide association studies of HDL cholesterol response to statins.
Academic Article KLB is associated with alcohol drinking, and its gene product ß-Klotho is necessary for FGF21 regulation of alcohol preference.
Academic Article Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.
Academic Article SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function.
Academic Article Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study.
Academic Article Understanding AAA Pathobiology: A GWAS Leads the Way.
Academic Article Rare and low-frequency coding variants alter human adult height.
Academic Article Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.
Academic Article Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk.
Academic Article Assessing the causal relationship between obesity and venous thromboembolism through a Mendelian Randomization study.
Academic Article Corrigendum: 1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function.
Academic Article Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.
Academic Article Ranking and characterization of established BMI and lipid associated loci as candidates for gene-environment interactions.
Academic Article 1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function.
Academic Article Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.
Academic Article Meta-analysis identifies five novel loci associated with endometriosis highlighting key genes involved in hormone metabolism.
Academic Article Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.
Academic Article Analysis of potential protein-modifying variants in 9000 endometriosis patients and 150000 controls of European ancestry.
Academic Article Genetic Interactions with Age, Sex, Body Mass Index, and Hypertension in Relation to Atrial Fibrillation: The AFGen Consortium.
Academic Article Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.
Academic Article Shared genetic risk between migraine and coronary artery disease: A genome-wide analysis of common variants.
Academic Article Corrigendum: Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.
Academic Article New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475?000 Individuals.
Academic Article Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity.
Academic Article Adiposity and Genetic Factors in Relation to Triglycerides and Triglyceride-Rich Lipoproteins in the Women's Genome Health Study.
Academic Article Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.
Grant Causality and/or shared physiology linking plasma lipids and blood pressure to migraine
Academic Article Genome-wide association meta-analysis of fish and EPA+DHA consumption in 17 US and European cohorts.
Academic Article Peering Into the Future of CAD Genomics.
Academic Article A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.
Academic Article Testosterone Pathway Genetic Polymorphisms in Relation to Primary Open-Angle Glaucoma: An Analysis in Two Large Datasets.
Academic Article Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.
Academic Article Blood Eosinophil Count and Metabolic, Cardiac and Pulmonary Outcomes: A Mendelian Randomization Study.
Academic Article Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.
Academic Article Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney.
Academic Article Analysis of shared heritability in common disorders of the brain.
Academic Article Multi-ethnic genome-wide association study for atrial fibrillation.
Academic Article Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.
Academic Article Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium.
Academic Article Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.
Academic Article Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.
Academic Article Gene-Based Elevated Triglycerides and Type 2 Diabetes Mellitus Risk in the Women's Genome Health Study.
Academic Article Trans-ethnic association study of blood pressure determinants in over 750,000 individuals.
Academic Article Association Between Titin Loss-of-Function Variants and Early-Onset Atrial Fibrillation.
Academic Article Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.
Academic Article A large-scale exome array analysis of venous thromboembolism.
Academic Article Assessment of the Relationship Between Genetic Determinants of Thyroid Function and Atrial Fibrillation: A Mendelian Randomization Study.
Academic Article Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
Academic Article Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution.
Academic Article Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
Academic Article A genome-wide association study of bitter and sweet beverage consumption.
Academic Article Erratum: A genome-wide association study of bitter and sweet beverage consumption.
Academic Article Mendelian randomization evaluation of causal effects of fibrinogen on incident coronary heart disease.
Academic Article Genetic Correlations Between Diabetes and Glaucoma: An Analysis of Continuous and Dichotomous Phenotypes.
Academic Article A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure.
Academic Article A catalog of genetic loci associated with kidney function from analyses of a million individuals.
Academic Article Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.
Academic Article Genome-wide analysis of dental caries and periodontitis combining clinical and self-reported data.
Academic Article Quality of dietary fat and genetic risk of type 2 diabetes: individual participant data meta-analysis.
Academic Article Genomic and transcriptomic association studies identify 16 novel susceptibility loci for venous thromboembolism.
Academic Article Genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis.
Academic Article Effect of genetic liability to migraine on coronary artery disease and atrial fibrillation: a Mendelian randomization study.
Academic Article Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9.
Academic Article Statin-induced LDL cholesterol response and type 2 diabetes: a bidirectional two-sample Mendelian randomization study.
Academic Article Hypothyroidism and Kidney Function: A Mendelian Randomization Study.
Academic Article Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure.
Academic Article Mitochondrial genome-wide association study of migraine - the HUNT Study.
Academic Article Shared Molecular Genetic Mechanisms Underlie Endometriosis and Migraine Comorbidity.
Academic Article Could vitamin D reduce obesity-associated inflammation? Observational and Mendelian randomization study.
Academic Article Identifying blood pressure loci whose effects are modulated by multiple lifestyle exposures.
Academic Article Effect of genetic liability to migraine on cognition and brain volume: A Mendelian randomization study.
Academic Article Pleiotropy-Based Decomposition of Genetic Risk Scores: Association and Interaction Analysis for Type 2 Diabetes and CAD.
Academic Article Smoking-by-genotype interaction in type 2 diabetes risk and fasting glucose.
Academic Article Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci.
Academic Article Mendelian randomization analysis does not support causal associations of birth weight with hypertension risk and blood pressure in adulthood.
Academic Article Role of Rare and Low-Frequency Variants in Gene-Alcohol Interactions on Plasma Lipid Levels.
Academic Article A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine.
Academic Article Genetic analysis of endometriosis and depression identifies shared loci and implicates causal links with gastric mucosa abnormality.
Academic Article Genome-wide association study identifies 48 common genetic variants associated with handedness.
Academic Article Habitual sleep disturbances and migraine: a Mendelian randomization study.
Academic Article Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals.
Academic Article Genetic loci associated with prevalent and incident myocardial infarction and coronary heart disease in the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium.
Academic Article Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program.
Academic Article Association Between Hemostatic Profile and Migraine: A Mendelian Randomization Analysis.
Academic Article Genome-wide gene-diet interaction analysis in the UK Biobank identifies novel effects on hemoglobin A1c.
Academic Article The trans-ancestral genomic architecture of glycemic traits.
Academic Article Genetic insights into biological mechanisms governing human ovarian ageing.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.