Harvard Catalyst Profiles

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One or more keywords matched the following items that are connected to Reed, Robin
Item TypeName
Academic Article Human homologs of yeast prp16 and prp17 reveal conservation of the mechanism for catalytic step II of pre-mRNA splicing.
Academic Article An upstream AG determines whether a downstream AG is selected during catalytic step II of splicing.
Academic Article Serine/arginine-rich protein-dependent suppression of exon skipping by exonic splicing enhancers.
Academic Article SR proteins function in coupling RNAP II transcription to pre-mRNA splicing.
Academic Article Human step II splicing factor hSlu7 functions in restructuring the spliceosome between the catalytic steps of splicing.
Academic Article Evidence that U5 snRNP recognizes the 3' splice site for catalytic step II in mammals.
Academic Article Weak definition of IKBKAP exon 20 leads to aberrant splicing in familial dysautonomia.
Academic Article Cotranscriptional recruitment of the serine-arginine-rich (SR)-like proteins Gbp2 and Hrb1 to nascent mRNA via the TREX complex.
Academic Article A novel set of spliceosome-associated proteins and the essential splicing factor PSF bind stably to pre-mRNA prior to catalytic step II of the splicing reaction.
Academic Article A model in vitro system for co-transcriptional splicing.
Academic Article Small-scale nuclear extracts for functional assays of gene-expression machineries.
Academic Article An extensive network of coupling among gene expression machines.
Academic Article Functional coupling of RNAP II transcription to spliceosome assembly.
Concept RNA Polymerase II
Concept Poly(A)-Binding Proteins
Academic Article In vitro systems for coupling RNAP II transcription to splicing and polyadenylation.
Academic Article Primary microRNA processing is functionally coupled to RNAP II transcription in vitro.
Academic Article FUS functions in coupling transcription to splicing by mediating an interaction between RNAP II and U1 snRNP.
Grant Functional Coupling of Steps in Genes Expression
Grant Functional Coupling of Steps in Genes Expression
Grant RNA Processing Machines in Biology and Disease
Academic Article Interactome analyses revealed that the U1 snRNP machinery overlaps extensively with the RNAP II machinery and contains multiple ALS/SMA-causative proteins.
Academic Article In Vitro System for Coupling RNAP II Transcription to Primary microRNA Processing and a Three-Way System for RNAP II Transcription/Splicing/microRNA Processing.
Academic Article The neurodegenerative diseases ALS and SMA are linked at the molecular level via the ASC-1 complex.
Search Criteria
  • Poly A Binding Protein
  • II
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.