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Search Results to George C. Tsokos, M.D.

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Item TypeName
Academic Article PP2A dephosphorylates Elf-1 and determines the expression of CD3zeta and FcRgamma in human systemic lupus erythematosus T cells.
Academic Article Transcriptional repression of interleukin-2 in human systemic lupus erythematosus.
Academic Article Protein kinase C-theta participates in the activation of cyclic AMP-responsive element-binding protein and its subsequent binding to the -180 site of the IL-2 promoter in normal human T lymphocytes.
Academic Article Systemic lupus erythematosus serum IgG increases CREM binding to the IL-2 promoter and suppresses IL-2 production through CaMKIV.
Academic Article Protein phosphatase 2A is a negative regulator of IL-2 production in patients with systemic lupus erythematosus.
Academic Article Phosphorylation and O-linked glycosylation of Elf-1 leads to its translocation to the nucleus and binding to the promoter of the TCR zeta-chain.
Academic Article NF-kappaB regulates the expression of the human complement receptor 2 gene.
Academic Article Direct transfer of p65 into T lymphocytes from systemic lupus erythematosus patients leads to increased levels of interleukin-2 promoter activity.
Academic Article Activation of the Ets transcription factor Elf-1 requires phosphorylation and glycosylation: defective expression of activated Elf-1 is involved in the decreased TCR zeta chain gene expression in patients with systemic lupus erythematosus.
Academic Article Transcriptional regulation of IL-2 in health and autoimmunity.
Academic Article c-Jun and Ets2 proteins regulate expression of spleen tyrosine kinase in T cells.
Academic Article Molecular basis of deficient IL-2 production in T cells from patients with systemic lupus erythematosus.
Academic Article The cyclic adenosine 5'-monophosphate response element modulator suppresses IL-2 production in stimulated T cells by a chromatin-dependent mechanism.
Academic Article The cyclic AMP response element modulator regulates transcription of the TCR zeta-chain.
Academic Article Defective production of functional 98-kDa form of Elf-1 is responsible for the decreased expression of TCR zeta-chain in patients with systemic lupus erythematosus.
Academic Article Transcriptional activation of the human inducible nitric-oxide synthase promoter by Kruppel-like factor 6.
Academic Article Methylation status of CpG islands flanking a cAMP response element motif on the protein phosphatase 2Ac alpha promoter determines CREB binding and activity.
Academic Article cAMP responsive element modulator: a critical regulator of cytokine production.
Academic Article cAMP response element modulator a controls IL2 and IL17A expression during CD4 lineage commitment and subset distribution in lupus.
Academic Article Estrogen upregulates cyclic AMP response element modulator a expression and downregulates interleukin-2 production by human T lymphocytes.
Academic Article cAMP-responsive element modulator a (CREMa) contributes to decreased Notch-1 expression in T cells from patients with active systemic lupus erythematosus (SLE).
Academic Article Multiple transcription factors regulate the inducible expression of the human complement receptor 2 promoter.
Academic Article The transcriptional repressor cAMP response element modulator alpha interacts with histone deacetylase 1 to repress promoter activity.
Academic Article Promoter hypomethylation results in increased expression of protein phosphatase 2A in T cells from patients with systemic lupus erythematosus.
Academic Article Defective CD3zeta chain expression in Herpesvirus saimiri (HVS)-derived T-cell lines in gastric adenocarcinoma.
Academic Article Elf-1 binds to GGAA elements on the FcRgamma promoter and represses its expression.
Academic Article Polymorphisms/mutations of TCR-zeta-chain promoter and 3' untranslated region and selective expression of TCR zeta-chain with an alternatively spliced 3' untranslated region in patients with systemic lupus erythematosus.
Academic Article Dexamethasone modulates TCR zeta chain expression and antigen receptor-mediated early signaling events in human T lymphocytes.
Academic Article Transcriptional activation of the cAMP-responsive modulator promoter in human T cells is regulated by protein phosphatase 2A-mediated dephosphorylation of SP-1 and reflects disease activity in patients with systemic lupus erythematosus.
Academic Article CD3-T cell receptor co-stimulation through SLAMF3 and SLAMF6 receptors enhances ROR?t recruitment to the IL17A promoter in human T lymphocytes.
Academic Article The cyclic AMP response element modulator {alpha} suppresses CD86 expression and APC function.
Academic Article Cyclic adenosine 5'-monophosphate response element modulator is responsible for the decreased expression of c-fos and activator protein-1 binding in T cells from patients with systemic lupus erythematosus.
Academic Article Antisense cyclic adenosine 5'-monophosphate response element modulator up-regulates IL-2 in T cells from patients with systemic lupus erythematosus.
Academic Article Increased levels of NF-ATc2 differentially regulate CD154 and IL-2 genes in T cells from patients with systemic lupus erythematosus.
Academic Article Induction of the CTLA-4 gene in human lymphocytes is dependent on NFAT binding the proximal promoter.
Concept Promoter Regions, Genetic
Academic Article Transcription factor Ikaros represses protein phosphatase 2A (PP2A) expression through an intronic binding site.
Academic Article Serine Arginine-Rich Splicing Factor 1 (SRSF1) Contributes to the Transcriptional Activation of CD3? in Human T Cells.
Grant REGULATION OF COMPLEMENT RECEPTOR GENE EXPRESSION

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  • Promoter Regions Genetic