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One or more keywords matched the following items that are connected to Gygi, Steven
Item TypeName
Academic Article Quantitative analysis of methadone and two major metabolites in hair by positive chemical ionization ion trap mass spectrometry.
Academic Article Characterization of mouse spleen cells by subtractive proteomics.
Academic Article An iterative statistical approach to the identification of protein phosphorylation motifs from large-scale data sets.
Academic Article Optimization and use of peptide mass measurement accuracy in shotgun proteomics.
Academic Article Quantitative analysis of complex protein mixtures using isotope-coded affinity tags.
Academic Article Mass spectrometric analysis of the editosome and other multiprotein complexes in Trypanosoma brucei.
Academic Article An integrated microfluidics-tandem mass spectrometry system for automated protein analysis.
Academic Article Measuring gene expression by quantitative proteome analysis.
Academic Article Phosphoproteome analysis of Drosophila melanogaster embryos.
Academic Article The SCX/IMAC enrichment approach for global phosphorylation analysis by mass spectrometry.
Academic Article Gas-phase rearrangements do not affect site localization reliability in phosphoproteomics data sets.
Academic Article Quantitative proteomic analysis using a MALDI quadrupole time-of-flight mass spectrometer.
Academic Article Proteomics: the move to mixtures.
Academic Article Automation of nanoscale microcapillary liquid chromatography-tandem mass spectrometry with a vented column.
Academic Article Towards an integrated analytical technology for the generation of multidimensional protein expression maps.
Academic Article Human ISG15 conjugation targets both IFN-induced and constitutively expressed proteins functioning in diverse cellular pathways.
Academic Article Enhanced analysis of metastatic prostate cancer using stable isotopes and high mass accuracy instrumentation.
Academic Article Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response.
Academic Article The effects of mass accuracy, data acquisition speed, and search algorithm choice on peptide identification rates in phosphoproteomics.
Academic Article Electrophoresis combined with novel mass spectrometry techniques: powerful tools for the analysis of proteins and proteomes.
Academic Article Complementary profiling of gene expression at the transcriptome and proteome levels in Saccharomyces cerevisiae.
Academic Article Absolute quantification of proteins and phosphoproteins from cell lysates by tandem MS.
Academic Article Intensity-based protein identification by machine learning from a library of tandem mass spectra.
Academic Article Serum-stimulated, rapamycin-sensitive phosphorylation sites in the eukaryotic translation initiation factor 4GI.
Academic Article Four related proteins of the Trypanosoma brucei RNA editing complex.
Academic Article The gammaTuRC revisited: a comparative analysis of interphase and mitotic human gammaTuRC redefines the set of core components and identifies the novel subunit GCP8.
Academic Article Cdc28-dependent regulation of the Cdc5/Polo kinase.
Academic Article A comparison of phenobarbital and codeine incorporation into pigmented and nonpigmented rat hair.
Academic Article Hierarchical phosphorylation of the translation inhibitor 4E-BP1.
Academic Article Comprehensive proteomic analysis of the human spliceosome.
Academic Article Evaluation of multidimensional chromatography coupled with tandem mass spectrometry (LC/LC-MS/MS) for large-scale protein analysis: the yeast proteome.
Academic Article Mechanism of group IVA cytosolic phospholipase A(2) activation by phosphorylation.
Academic Article Association of the histone methyltransferase Set2 with RNA polymerase II plays a role in transcription elongation.
Academic Article A site-specific, multiplexed kinase activity assay using stable-isotope dilution and high-resolution mass spectrometry.
Academic Article The absolute quantification strategy: a general procedure for the quantification of proteins and post-translational modifications.
Academic Article Weighing in on ubiquitin: the expanding role of mass-spectrometry-based proteomics.
Academic Article Distribution of codeine and morphine into rat hair after long-term daily dosing with codeine.
Academic Article Large-scale phosphorylation analysis of mouse liver.
Academic Article Mek1 kinase is regulated to suppress double-strand break repair between sister chromatids during budding yeast meiosis.
Academic Article The energy sensor AMP-activated protein kinase directly regulates the mammalian FOXO3 transcription factor.
Academic Article Identification of 14-3-3epsilon substrates from embryonic murine brain.
Academic Article Phosphoproteomic analysis of the developing mouse brain.
Academic Article A proteomic strategy for gaining insights into protein sumoylation in yeast.
Academic Article Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.
Academic Article Evaluation of two-dimensional gel electrophoresis-based proteome analysis technology.
Academic Article Mass spectrometric analysis of type 1 inositol 1,4,5-trisphosphate receptor ubiquitination.
Academic Article Neutralizing positive charges at the surface of a protein lowers its rate of amide hydrogen exchange without altering its structure or increasing its thermostability.
Academic Article A quantitative proteomic analysis of growth factor-induced compositional changes in lipid rafts of human smooth muscle cells.
Academic Article Quantitative analysis of in vitro ubiquitinated cyclin B1 reveals complex chain topology.
Academic Article A UAF1-containing multisubunit protein complex regulates the Fanconi anemia pathway.
Academic Article A probability-based approach for high-throughput protein phosphorylation analysis and site localization.
Academic Article Incorporation of drugs for the treatment of substance abuse into pigmented and nonpigmented hair.
Academic Article Sensitive multiplexed analysis of kinase activities and activity-based kinase identification.
Academic Article Assigning spectrum-specific P-values to protein identifications by mass spectrometry.
Academic Article Proteomics identifies multipotent and low oncogenic risk stem cells of the spleen.
Academic Article Comparative evaluation of mass spectrometry platforms used in large-scale proteomics investigations.
Academic Article Transcriptional role of cyclin D1 in development revealed by a genetic-proteomic screen.
Academic Article Phosphorylation of the eukaryotic translation initiation factor 4E-transporter (4E-T) by c-Jun N-terminal kinase promotes stress-dependent P-body assembly.
Academic Article Semiquantitative proteomic analysis of rat forebrain postsynaptic density fractions by mass spectrometry.
Academic Article SKAR is a specific target of S6 kinase 1 in cell growth control.
Academic Article Quantitative cancer proteomics: stable isotope labeling with amino acids in cell culture (SILAC) as a tool for prostate cancer research.
Academic Article Prokaryotic ubiquitin-like protein (Pup) proteome of Mycobacterium tuberculosis [corrected] .
Academic Article Protein profiling with cleavable isotope-coded affinity tag (cICAT) reagents: the yeast salinity stress response.
Academic Article Discrete serum protein signatures discriminate between human retrovirus-associated hematologic and neurologic disease.
Academic Article Proteomic profiling of ClpXP substrates after DNA damage reveals extensive instability within SOS regulon.
Academic Article The impact of peptide abundance and dynamic range on stable-isotope-based quantitative proteomic analyses.
Academic Article Hyperplexing: a method for higher-order multiplexed quantitative proteomics provides a map of the dynamic response to rapamycin in yeast.
Academic Article SUMOylation of pancreatic glucokinase regulates its cellular stability and activity.
Academic Article Proteomic profiling of gamma-secretase substrates and mapping of substrate requirements.
Academic Article Regulation of meiotic recombination via Mek1-mediated Rad54 phosphorylation.
Academic Article Ubiquitin-like protein involved in the proteasome pathway of Mycobacterium tuberculosis.
Academic Article The absolute quantification strategy: application to phosphorylation profiling of human separase serine 1126.
Academic Article MS3 eliminates ratio distortion in isobaric multiplexed quantitative proteomics.
Academic Article Proteome analysis: biological assay or data archive?
Academic Article Quantitative proteome analysis: methods and applications.
Academic Article Dual inhibition of sister chromatid separation at metaphase.
Academic Article Increasing the multiplexing capacity of TMTs using reporter ion isotopologues with isobaric masses.
Academic Article Toward a high-throughput approach to quantitative proteomic analysis: expression-dependent protein identification by mass spectrometry.
Academic Article Protein analysis by mass spectrometry and sequence database searching: tools for cancer research in the post-genomic era.
Academic Article The ubiquitin-interacting motif protein, S5a, is ubiquitinated by all types of ubiquitin ligases by a mechanism different from typical substrate recognition.
Academic Article Association of two novel proteins, TbMP52 and TbMP48, with the Trypanosoma brucei RNA editing complex.
Academic Article Profiling Y561-dependent and -independent substrates of CSF-1R in epithelial cells.
Academic Article A solid phase extraction-based platform for rapid phosphoproteomic analysis.
Academic Article A large-scale method to measure absolute protein phosphorylation stoichiometries.
Academic Article A CaMKIIß signaling pathway at the centrosome regulates dendrite patterning in the brain.
Academic Article Purification and architecture of the ubiquitous Wave complex.
Academic Article Mass spectrometry and proteomics.
Academic Article Haptoglobin-alpha subunit as potential serum biomarker in ovarian cancer: identification and characterization using proteomic profiling and mass spectrometry.
Academic Article Tra1 has specific regulatory roles, rather than global functions, within the SAGA co-activator complex.
Academic Article Evaluation of HCD- and CID-type fragmentation within their respective detection platforms for murine phosphoproteomics.
Academic Article Selenoprotein K binds multiprotein complexes and is involved in the regulation of endoplasmic reticulum homeostasis.
Academic Article Quantitative phosphorylation profiling of the ERK/p90 ribosomal S6 kinase-signaling cassette and its targets, the tuberous sclerosis tumor suppressors.
Academic Article A quantitative atlas of mitotic phosphorylation.
Academic Article The S. pombe SAGA complex controls the switch from proliferation to sexual differentiation through the opposing roles of its subunits Gcn5 and Spt8.
Academic Article Defining the human deubiquitinating enzyme interaction landscape.
Academic Article Sas-4 provides a scaffold for cytoplasmic complexes and tethers them in a centrosome.
Academic Article Accurate multiplexed proteomics at the MS2 level using the complement reporter ion cluster.
Academic Article Mapping and analysis of phosphorylation sites: a quick guide for cell biologists.
Academic Article Large-scale characterization of HeLa cell nuclear phosphoproteins.
Academic Article Recruitment of Xenopus Scc2 and cohesin to chromatin requires the pre-replication complex.
Academic Article Identification of protein components in in vivo human acquired enamel pellicle using LC-ESI-MS/MS.
Academic Article RNAi-mediated targeting of heterochromatin by the RITS complex.
Academic Article SILVER helps assign peptides to tandem mass spectra using intensity-based scoring.
Academic Article Purification of active TFIID from Saccharomyces cerevisiae. Extensive promoter contacts and co-activator function.
Academic Article Target-decoy search strategy for increased confidence in large-scale protein identifications by mass spectrometry.
Academic Article Certain pairs of ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s) synthesize nondegradable forked ubiquitin chains containing all possible isopeptide linkages.
Academic Article Assessing enzyme activities using stable isotope labeling and mass spectrometry.
Academic Article Phosphoproteome analysis of fission yeast.
Academic Article Target-decoy search strategy for mass spectrometry-based proteomics.
Academic Article Proteome-wide systems analysis of a cellulosic biofuel-producing microbe.
Academic Article A high-throughput, multiplexed kinase assay using a benchtop orbitrap mass spectrometer to investigate the effect of kinase inhibitors on kinase signaling pathways.
Academic Article The tumor suppressor DAP kinase is a target of RSK-mediated survival signaling.
Academic Article A comparative proteomic analysis of human and rat embryonic cerebrospinal fluid.
Academic Article Evaluation of the utility of neutral-loss-dependent MS3 strategies in large-scale phosphorylation analysis.
Concept Spectrometry, Mass, Electrospray Ionization
Concept Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
Concept Gas Chromatography-Mass Spectrometry
Concept Tandem Mass Spectrometry
Concept Mass Spectrometry
Academic Article Quantitative comparison of the fasted and re-fed mouse liver phosphoproteomes using lower pH reductive dimethylation.
Academic Article Increasing throughput in targeted proteomics assays: 54-plex quantitation in a single mass spectrometry run.
Academic Article Correlation profiling for determining kinase-substrate relationships.
Academic Article The influence of signals from chilled roots on the proteome of shoot tissues in rice seedlings.
Academic Article Mass spectrometry based method to increase throughput for kinome analyses using ATP probes.
Academic Article Heterochromatic gene silencing by activator interference and a transcription elongation barrier.
Academic Article Identification of a unique TGF-ß-dependent molecular and functional signature in microglia.
Academic Article MultiNotch MS3 enables accurate, sensitive, and multiplexed detection of differential expression across cancer cell line proteomes.
Academic Article Deep proteomics of the Xenopus laevis egg using an mRNA-derived reference database.
Academic Article Msp1/ATAD1 maintains mitochondrial function by facilitating the degradation of mislocalized tail-anchored proteins.
Academic Article Large-scale proteomic characterization of melanoma expressed proteins reveals nestin and vimentin as biomarkers that can potentially distinguish melanoma subtypes.
Academic Article Mechanism-based proteomic screening identifies targets of thioredoxin-like proteins.
Academic Article A comprehensive proteomic and phosphoproteomic analysis of yeast deletion mutants of 14-3-3 orthologs and associated effects of rapamycin.
Academic Article eIF1A augments Ago2-mediated Dicer-independent miRNA biogenesis and RNA interference.
Academic Article Effects of MEK inhibitors GSK1120212 and PD0325901 in vivo using 10-plex quantitative proteomics and phosphoproteomics.
Academic Article Evaluating multiplexed quantitative phosphopeptide analysis on a hybrid quadrupole mass filter/linear ion trap/orbitrap mass spectrometer.
Academic Article A mass-tolerant database search identifies a large proportion of unassigned spectra in shotgun proteomics as modified peptides.
Academic Article The BioPlex Network: A Systematic Exploration of the Human Interactome.
Academic Article Comprehensive Temporal Protein Dynamics during the Diauxic Shift in Saccharomyces cerevisiae.
Academic Article Generation of multiple reporter ions from a single isobaric reagent increases multiplexing capacity for quantitative proteomics.
Academic Article Global Analysis of Protein Expression and Phosphorylation Levels in Nicotine-Treated Pancreatic Stellate Cells.
Academic Article Detection and Quantitation of Circulating Human Irisin by Tandem Mass Spectrometry.
Academic Article Proteome-wide quantitative multiplexed profiling of protein expression: carbon-source dependency in Saccharomyces cerevisiae.
Academic Article Proteomics of Primary Cilia by Proximity Labeling.
Academic Article Defining the consequences of genetic variation on a proteome-wide scale.
Grant New and Disruptive Technologies to Study Ubiquitin Biology through Sample Multiplexing
Academic Article A Triple Knockout (TKO) Proteomics Standard for Diagnosing Ion Interference in Isobaric Labeling Experiments.
Academic Article Quantitative mass spectrometry-based multiplexing compares the abundance of 5000 S. cerevisiae proteins across 10 carbon sources.
Academic Article Ubiquitin-Dependent Modification of Skeletal Muscle by the Parasitic Nematode, Trichinella spiralis.
Academic Article Highly Multiplexed Quantitative Mass Spectrometry Analysis of Ubiquitylomes.
Academic Article LIN28 phosphorylation by MAPK/ERK couples signalling to the post-transcriptional control of pluripotency.
Academic Article Neutral Loss Is a Very Common Occurrence in Phosphotyrosine-Containing Peptides Labeled with Isobaric Tags.
Academic Article A Strategy to Combine Sample Multiplexing with Targeted Proteomics Assays for High-Throughput Protein Signature Characterization.
Academic Article Multiplexed Phosphoproteomic Profiling Using Titanium Dioxide and Immunoaffinity Enrichments Reveals Complementary Phosphorylation Events.
Academic Article Proteome-Wide Protein Expression Profiling Across Five Pancreatic Cell Lines.
Academic Article Architecture of the human interactome defines protein communities and disease networks.
Academic Article Aminoglycoside-driven biosynthesis of selenium-deficient Selenoprotein P.
Academic Article Pseudomonas aeruginosa Proteome under Hypoxic Stress Conditions Mimicking the Cystic Fibrosis Lung.
Academic Article Age-related neurodegenerative disease associated pathways identified in retinal and vitreous proteome from human glaucoma eyes.
Academic Article BioPlex Display: An Interactive Suite for Large-Scale AP-MS Protein-Protein Interaction Data.
Academic Article Filter-Based Protein Digestion (FPD): A Detergent-Free and Scaffold-Based Strategy for TMT Workflows.
Academic Article Multiplexed Isobaric Tag-Based Profiling of Seven Murine Tissues Following In Vivo Nicotine Treatment Using a Minimalistic Proteomics Strategy.
Academic Article An Internal Standard for Assessing Phosphopeptide Recovery from Metal Ion/Oxide Enrichment Strategies.
Academic Article Isobaric Tag-Based Protein Profiling of a Nicotine-Treated Alpha7 Nicotinic Receptor-Null Human Haploid Cell Line.
Academic Article Streamlined Tandem Mass Tag (SL-TMT) Protocol: An Efficient Strategy for Quantitative (Phospho)proteome Profiling Using Tandem Mass Tag-Synchronous Precursor Selection-MS3.
Academic Article Proteomic profiling of yeast heterochromatin connects direct physical and genetic interactions.
Academic Article TKO6: A Peptide Standard To Assess Interference for Unit-Resolved Isobaric Labeling Platforms.
Academic Article The effects of nonignorable missing data on label-free mass spectrometry proteomics experiments.
Academic Article Active Instrument Engagement Combined with a Real-Time Database Search for Improved Performance of Sample Multiplexing Workflows.
Academic Article Characterization and Optimization of Multiplexed Quantitative Analyses Using High-Field Asymmetric-Waveform Ion Mobility Mass Spectrometry.
Academic Article TomahaqCompanion: A Tool for the Creation and Analysis of Isobaric Label Based Multiplexed Targeted Assays.
Academic Article Multiplexed Relative Quantitation with Isobaric Tagging Mass Spectrometry Reveals Class I Major Histocompatibility Complex Ligand Dynamics in Response to Doxorubicin.
Academic Article An expanded mouse testis transcriptome and mass spectrometry defines novel proteins.
Academic Article High-density chemical cross-linking for modeling protein interactions.
Academic Article Correction to Characterization and Optimization of Multiplexed Quantitative Analyses Using High-Field Asymmetric-Waveform Ion Mobility Mass Spectrometry.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.